A5005750675- Genetic and phenotypic traits in livestock
- Animal Nutrition and Physiology
- Genetic Mapping and Diversity in Plants and Animals
- Salmonella and Campylobacter epidemiology
- Livestock and Poultry Management
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Silkworms and Sericulture Research
- Immune Response and Inflammation
- Garlic and Onion Studies
- dental development and anomalies
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Viral gastroenteritis research and epidemiology
- Animal Genetics and Reproduction
- Phytoestrogen effects and research
- Soybean genetics and cultivation
- Livestock Farming and Management
- Plant Reproductive Biology
- RNA Research and Splicing
- Oral and Maxillofacial Pathology
- Cancer-related gene regulation
- Heat shock proteins research
Poultry Research Institute
2013-2023
Chinese Academy of Agricultural Sciences
2016-2021
Tulane University
2000
The comb, as a secondary sexual character, is an important trait in chicken. Indicators of comb length (CL), height (CH), and weight (CW) are often selected production. DNA-based marker-assisted selection could help chicken breeders to accelerate genetic improvement for or related economic characters by early selection. Although number quantitative loci (QTL) candidate genes have been identified with advances molecular genetics, underlying traits limited. aim the study was use genome-wide...
Abstract Follicular development has a major impact on reproductive performance. Most previous researchers focused molecular mechanisms of follicular development. The genetic architecture underlying the number follicle, however, yet not to be thoroughly defined in chicken. Here we report genome-wide association study for determining numbers follicles large F 2 resource population. results showed heritability were low moderate (0.05–0.28) pre-ovulatory (POF), small yellow (SYF) and atresia...
Bone size is an important trait for chickens because of its association with osteoporosis in layers and meat production broilers. Here, we employed high density genotyping platforms to detect candidate genes bone traits. Estimates the narrow heritabilities ranged from 0.37 ± 0.04 shank length 0.59 tibia length. The dominance heritability was 0.12 Using a linear mixed model approach, identified promising locus within NCAPG on chromosome 4, which associated mass, femur area, In addition, three...
Daidzein has become increasingly popular as a dietary supplement, particularly for postpeak-estrus animals, safe and natural alternative estrogen-like compound. However, there is little available safety data of daidzein in laying hens. A study was conducted to examine if high-dose affected the hens, including mortality, performance, egg quality, hematological parameters, clinical chemical organ development hatchability. total 2,448 42-wk-old Rugao hens were randomly assigned 4 groups with 6...
Immune traits play pivotal roles in animal immune capacity development and disease resistance. Single nucleotide polymorphisms (SNPs) are common forms of genetic variations among individuals, which thought to account for the majority inherited phenotypic variations. In this study, we performed genomewide association, using Illumina 60K SNP BeadChip studies detect molecular markers candidate genes associated with an F2 population. Sixteen were measured. We identified 85 significant SNPs (p <...
Albumen quality is a leading economic trait in the chicken industry. Major studies have paid attention to genetic architecture underlying albumen quality. However, putative quantitative locus (QTL) for this still unclear. In genome-wide association study, we used an F2 resource population study longitudinal Seven single-nucleotide polymorphism (SNP) loci were found be significantly ( p<8.43×10-7 ) related by univariate analysis, while 11 SNPs associated with multivariate analysis. A QTL on...
Molecular genetic tools provide a method for improving the breeding selection of chickens (Gallus gallus). Although some studies have identified genes affecting egg quality, little is known about responsible oviduct development. To address this issue, here we used genome-wide association (GWA) study to detect or genomic regions that are related development in chicken F2 resource population by employing high-density 600 K single-nucleotide polymorphism (SNP) arrays. For length and weight,...
Chicken Toll-like receptor 15 (ChTLR15) has been shown to participate in immune activation response various pathogens and the innate defence against infection. Two genetically distinct Chinese breeds of chicken (Qinyuan Partridge Baier breeds) were used study correlation between ChTLR15 single nucleotide polymorphisms natural infection status salmonella hens, also examine genetic sex-specific effects on mRNA expression heterophils spleen during acute with Salmonella enterica serovar...
Objective Internal organs indirectly affect economic performance and well-being of animals. Study internal during later layer period will allow full utilization hens. Hence, we conducted a genome-wide association study (GWAS) to identify potential quantitative trait loci or genes that potentially contribute organ weight. Methods A total 1,512 chickens originating from White Leghorn Dongxiang Blue-Shelled were genotyped using high-density Affymetrix 600 K single nucleotide polymorphism (SNP)...
Small intestine length is an important physiological index that effected by nutrient intake and thus plays roles in growth egg-laying chickens. Although there are some studies about small length, little information available regarding the genetic architecture of intestine. The current study was conducted to investigate length. A total 1435 F2 hens from a White Leghorn Dongxiang reciprocal cross were phenotyped for duodenum lengths (DL), jejunum (JL) ileum (IL), genotyped using chicken 600 K...
To determine the genetic architecture underlying spent hen carcase traits, especially in late laying, we used 1512 hens generated from Dongxiang Blue-Shelled and White Leghorn chickens to implement genome-wide association studies by high-density arrays. A total of 266 loci that mapped (Gallus gallus chromosome) GGA1, GGA4 GGA27 were detected. After linkage disequilibrium analysis, five SNPs considered as candidate markers because they located on or near genes CKAP2, RB1, CCKAR, NCAPG...
Objective: Eggshells with a uniform color and intensity are important for egg production because many consumers assess the quality of an according to shell color. In present study, we evaluated influence dominant effects on variations in eggshell after 32 weeks crossbred population.Methods: This study was conducted using 7,878 records from 2,626 hens. Heritability estimated univariate animal model, which included inbreeding coefficients as fixed effect additive genetic, residuals random...
1. Salmonella enteritidis (SE) is reported as the most common food-borne pathogen transmitted through poultry products. The natural resistance-associated macrophage protein 1 (NRAMP1) a candidate gene associated with SE-mediated immune response and related to phagocytosis of SE. In this study, classical single-nucleotide polymorphism (SNP) G2357A in exon 8 NRAMP1 was detected. expression mRNA first investigated heterophil granulocytes spleen chicks from two different Chinese native breeds at...
The aim of this study was to assess the effects energy-restricted feeding during rearing on performance, uniformity, and development layer breeders at initiation laying period. A total 2400 8-week-old Rugao were randomly assigned one five groups (480 pullets per group) with eight replicates fed diets that nutritionally equal exception apparent metabolizable energy corrected for nitrogen (AMEn) content (2850, 2750, 2650, 2550, 2450 kcal AMEn/kg) from 8 18 weeks age. daily amount feed...