V. A. Ryzhov

ORCID: 0000-0002-0546-1805
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Research Areas
  • Magnetic and transport properties of perovskites and related materials
  • Advanced Condensed Matter Physics
  • Earthquake Detection and Analysis
  • Scientific Measurement and Uncertainty Evaluation
  • Sensor Technology and Measurement Systems
  • Nanoparticle-Based Drug Delivery
  • Rare-earth and actinide compounds
  • Ionosphere and magnetosphere dynamics
  • Characterization and Applications of Magnetic Nanoparticles
  • Multiferroics and related materials
  • Radiation Therapy and Dosimetry
  • Advanced Sensor Technologies Research
  • Heat shock proteins research
  • Advanced Measurement and Metrology Techniques
  • Physics of Superconductivity and Magnetism
  • GNSS positioning and interference
  • Solid-state spectroscopy and crystallography
  • Shape Memory Alloy Transformations
  • Cold Atom Physics and Bose-Einstein Condensates
  • Radioactive Decay and Measurement Techniques
  • Advanced MEMS and NEMS Technologies
  • Planetary Science and Exploration
  • Magnetic and Electromagnetic Effects
  • Plasma Diagnostics and Applications
  • Geomagnetism and Paleomagnetism Studies

Kazan Federal University
2009-2024

Petersburg Nuclear Physics Institute
2010-2023

Kurchatov Institute
2014-2023

Lappeenranta-Lahti University of Technology
2014-2017

Russian Academy of Sciences
1997-2015

Physico-Technical Institute
1987

Radiophysical Research Institute
1968

We have decelerated a supersonic beam of $^{174}\mathrm{YbF}$ molecules using switched sequence electrostatic field gradients. These are 7 times heavier than any previously decelerated. An alternating gradient structure allows us to decelerate and focus the in their ground state. show that decelerator exhibits axial transverse stability required bring rest. Our work significantly extends range amenable this powerful method cooling trapping.

10.1103/physrevlett.92.173002 article EN Physical Review Letters 2004-04-27

Targeting experimental orthotopic glioblastoma with chitosan-based superparamagnetic iron oxide nanoparticles (CS-DX-SPIONs) Maxim Shevtsov,1–4 Boris Nikolaev,5 Yaroslav Marchenko,5 Ludmila Yakovleva,5 Nikita Skvortsov,5 Anton Mazur,6 Peter Tolstoy,6 Vyacheslav Ryzhov,7 Gabriele Multhoff2 1Department of Cell Biotechnology, Institute Cytology the Russian Academy Sciences, St Petersburg, Russia; 2Department Radiation Immuno Oncology, Technische Universität München, Klinikum...

10.2147/ijn.s152461 article EN cc-by-nc International Journal of Nanomedicine 2018-03-01

The stress-inducible 72 kDa heat shock protein Hsp70 is known to be expressed on the membrane of highly aggressive tumor cells including high-grade gliomas, but not corresponding normal cells. Membrane (mHsp70) rapidly internalized into and thus targeting mHsp70 might provide a promising strategy for theranostics. Superparamagnetic iron oxide nanoparticles (SPIONs) are contrast negative agents that used detection tumors with MRI. Herein, we conjugated Hsp70-specific antibody (cmHsp70.1)...

10.1039/c5nr06521f article EN Nanoscale 2015-01-01

Abstract Magnetic hyperthermia (MH) harnesses the heat‐releasing properties of superparamagnetic iron oxide nanoparticles (SPIONs) and has potential to stimulate immune activation in tumor microenvironment whilst sparing surrounding normal tissues. To assess feasibility localized MH vivo, SPIONs are injected intratumorally their fate tracked by Zirconium‐89‐positron emission tomography, histological analysis, electron microscopy. Experiments show that an average 49% (21–87%, n = 9) retained...

10.1002/smll.202005241 article EN cc-by Small 2021-03-18

The effect of treatment conditions on the magnetic and magnetotransport properties A-site ordered PrBaMn2O6−δ manganites is examined. parent oxygen-stoichiometric PrBaMn2O6 samples were prepared from disordered Pr0.50Ba0.50MnO3 ones by using a 'two-step' synthesis method. most significant structural feature that MnO2 sublattice sandwiched two kinds rock-salt layers, PrOx BaO. demonstrates ferromagnetic metal to paramagnetic insulator transition with Curie point at about 320 K. These...

10.1088/0953-8984/17/41/019 article EN Journal of Physics Condensed Matter 2005-09-30

Abstract Functionalized superparamagnetic iron oxide nanoparticles (SPIONs) have emerged as potential clinical tools for cancer theranostics. Membrane‐bound 70 kDa heat shock protein (mHsp70) is ubiquitously expressed on the cell membrane of various tumor types but not normal cells and therefore provides a tumor‐specific target. The serine protease granzyme B (GrB) that produced an effector molecule by activated T NK has been shown to specifically target mHsp70 cells. Following binding...

10.1002/smll.201900205 article EN Small 2019-03-01

Abstract Mesoporous silica nanoparticles (MSNs) impregnated with zero-valent Fe (Fe(0) @ MCM-41) represent an attractive nanocarrier system for drug delivery into tumor cells. The major goal of this work was to assess whether MSNs can penetrate the blood-brain barrier in a glioblastoma rat model. Synthesized nanomaterials were characterized by energy dispersive X-ray spectroscopy, measurements diffraction, scanning electron microscopy and Mössbauer spectroscopy. For detection MR...

10.1038/srep29247 article EN cc-by Scientific Reports 2016-07-08

Abstract The chemical phase content, crystal structure, and magnetization for the doped anion‐deficient La 1– x Sr MnO 3– /2 ( = 0, 0.05, 0.10, 0.20, 0.30) manganites have been studied. samples undergo structural transition from O′‐orthorhombic to rhombohedric unit cell at > 0.10. As doping level oxygen deficiency increase show a number of magnetic transitions. In region 0.05 ≤ 0.20 are inhomogeneous ferromagnets while 0.30 they cluster spin glasses. temperature moment freezing is ∼45 K....

10.1002/pssb.200402143 article EN physica status solidi (b) 2005-01-27

We have developed a pulsed supersonic beam of slow, cold YbF molecular radicals with an intensity 1.4 × 109 molecules per steradian pulse in the X2 Σ+ (v = 0, N 0) ground state. The translational and rotational temperatures are equal. lowest temperature produced was K slowest centre-of-mass velocity 290 K. show that can be made either by ablating Yb metal into fluorine-bearing carrier gas or solid precursors pure inert gas. This source is suitable for injecting molecule decelerator...

10.1088/0953-4075/35/24/306 article EN Journal of Physics B Atomic Molecular and Optical Physics 2002-11-27

Colloidal particles consisted of individual nanosized magnetite grains on the surface silica cores were obtained by two-stage sol-gel technique.Size distribution and microstructure analyzed using atomic force microscopy, X-ray diffraction Nitrogen thermal desorption.Magnetic properties studied method longitudinal nonlinear response.It has been shown that nanoparticles have a size corresponding to superparamagnetic state but exhibit hysteresis properties.The phenomenon was explained...

10.4283/jmag.2015.20.3.221 article EN Journal of Magnetics 2015-09-30

Structural neutron diffraction investigations as well data on resistance, linear susceptibility, and second harmonic of magnetization are presented for ${}^{154}{\mathrm{Sm}}_{0.6}{\mathrm{Sr}}_{0.4}{\mathrm{MnO}}_{3}$ manganite. The structural studies reveal the unique Jahn-Teller (JT) character this compound which is established to exhibit a $\mathrm{Pbmn}$ space group. Unusual large coherent JT distortions found develop below ${T}_{\mathrm{JT}}\ensuremath{\approx}180 \mathrm{K}$ remain...

10.1103/physrevb.64.094432 article EN Physical review. B, Condensed matter 2001-08-14

Structural investigations (neutron diffraction and electron microscopy), as well data on resistance, magnetization, second harmonic of are presented for $^{154}\mathrm{Sm}_{0.5}{\mathrm{Sr}}_{0.5}\mathrm{Mn}{\mathrm{O}}_{3}$ manganite. The neutron studies reveal a structural phase transition at ${T}_{\mathit{st}}\ensuremath{\approx}135\phantom{\rule{0.3em}{0ex}}\mathrm{K}$ from high-temperature $Pbnm$ space group to mixture two phases, which coherently coupled by atomic positions but differ...

10.1103/physrevb.72.184432 article EN Physical Review B 2005-11-29

The effect of isovalent substitution rare-earth cations on the phase separation in half-doped manganites was studied example ${\mathrm{Sm}}_{0.32}{\mathrm{Pr}}_{0.18}{\mathrm{Sr}}_{0.5}{\mathrm{MnO}}_{3}$ by high-resolution neutron powder diffraction, beam depolarization, second-harmonic magnetic response, and magnetization resistivity measurements from 4 K up to room temperature higher. A structural transition orthorhombic $Pbnm$ a mixture monoclinic $P{2}_{1}/m$ phases observed upon...

10.1103/physrevb.100.184424 article EN Physical review. B./Physical review. B 2019-11-27

Magnetic parameters of magnetosomes inside the bacteria MSR-1, LBB-42, AMB-1, SP-1, BB-1, and SO-1 strains genus Magnetospirillum fixed by 5% formalin in nutrient medium were estimated measurements nonlinear longitudinal response to a weak ac magnetic field (NLR-M2) at room temperature. For AMB-1 strains, electron resonance (EMR) spectra with special X-band spectrometer for wide-line registration also carried out. To trace evolution state during long-term storage, freshly prepared samples...

10.3390/app13042431 article EN cc-by Applied Sciences 2023-02-14

The potential of standard methods radiation therapy is limited by the dose that can be safely delivered to tumor, which could too low for radical treatment. efficiency increased using radiosensitizers. In this study, we evaluated sensitizing biocompatible iron oxide nanoparticles coated with a dextran shell in A172 and Gl-Tr glioblastoma cells vitro. preincubated 24 h were exposed ionizing (X-ray, gamma, or proton) at doses 0.5-6 Gy, their viability was assessed Resazurin assay staining...

10.3390/ijms242015150 article EN International Journal of Molecular Sciences 2023-10-13

Despite multimodal approaches for the treatment of multiforme glioblastoma (GBM) advances in outcome have been very modest indicating necessity novel diagnostic and therapeutic strategies. Currently, mesenchymal stem cells (MSCs) represent a promising platform cell-based cancer therapies because their tumor-tropism, low immunogenicity, easy accessibility, isolation procedure, culturing. In present study, we assessed tumor-tropism biodistribution superparamagnetic iron oxide nanoparticle...

10.3390/biomedicines9111592 article EN cc-by Biomedicines 2021-11-01

Results of structural neutron diffraction study, magnetization, and electron spin resonance (ESR) measurements are presented for insulating ${\mathrm{Nd}}_{1\ensuremath{-}x}{\mathrm{Ba}}_{x}{\mathrm{MnO}}_{3}(x=0.25)$ with the Curie temperature ${T}_{C}\ensuremath{\approx}129\phantom{\rule{0.3em}{0ex}}\mathrm{K}$. Detailed analysis data is performed by using Pbnm space group in a range 4.2--300 K. The compound found to exhibit Jahn-Teller (JT) transition at...

10.1103/physrevb.72.134427 article EN Physical Review B 2005-10-27

The representative measurements of the second harmonic in ac magnetization complemented by neutron depolarization have been performed for single-crystal La0.85Sr0.15CoO3 temperature range 97 K < T 230 K, where occurrence a small fraction (~ 0.001) nanoscale ferromagnetic clusters (FMC) has found. Magnetic, geometrical and dynamical parameters FMC system evaluated 140 superparamagnetic regime installs, means formalism involving Fokker-Planck equation (FPE). With lowering temperature, amount...

10.1103/physrevb.92.014404 article EN Physical Review B 2015-07-06
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