The objectives of this study were to characterize the allelic and genotypic frequencies polymorphisms in µ-calpain calpastatin genes, assess their association with meat tenderness animal growth Nellore cattle.We evaluated 605 Genetics Molecular Research 16 (1): gmr16018957 animals at 24 months age, on average, slaughter.The determined for molecular markers CAPN316, CAPN530, CAPN4751, CAPN4753, UOGACAST1.Analyses 7, 14, 21 days maturation performed samples longissimus thoracis obtained...

The current research was conducted to estimate the heritability coefficients and genetic correlations for performance carcass body composition traits in a single sire broiler line. analyzed were BW at 38 d, ultrasound records of pectoral muscle depth, feed intake, conversion ratio, 42 d. eviscerated BW, breast weight, leg abdominal fat content, heart gizzard liver intestine weight. number observations varied between 4,120 29,040 each trait. (co)variance components, heritability, correlation...

We examined whether single-nucleotide polymorphisms (SNPs) in the calpain (CAPN) and calpastatin (CAST) genes, described from Bos primigenius taurus, are polymorphic Nellore cattle.We also looked for a possible association of linkage disequilibrium this polymorphism with tenderness longissimus dorsi muscle after 7, 14 21 days postmortem aging 638 purebred bulls.Meat was measured as Warner-Bratzler shear force.Additive dominance effects were tested SNPs three genotypic classes; substitution...

Fertility is among the most important economic traits in dairy cattle. Genomic prediction for cow fertility has received much attention last decade, while bull been largely overlooked. The goal of this study was to assess genomic using markers with large effect and functional annotation data. Sire conception rate (SCR) used as a measure service sire fertility. Dataset consisted 11.5 k U.S. Holstein bulls SCR records about 300 single nucleotide polymorphism (SNP) markers. analyses included...

The service sire has been recognized as an important factor affecting herd fertility in dairy cattle. Recent studies suggest that genetic factors explain part of the difference among Holstein sires. main objective this study was to dissect architecture US Jersey dataset included 1.5 K bulls with conception rate (SCR) records and 96 single nucleotide polymorphism (SNP) markers spanning whole genome. analysis whole-genome scans for both additive non-additive effects subsequent functional...

Natural and artificial selection leads to changes in certain regions of the genome resulting signatures that can reveal genes associated with selected traits. Selection may be identified using different methodologies, which some are based on detecting contiguous sequences homozygous identical-by-descent haplotypes, called runs homozygosity (ROH), or estimating fixation index (FST) genomic windows indicates genetic differentiation. This study aimed identify a paternal broiler TT line at...

Abstract Background Copy number variations (CNVs) are a major type of structural genomic variants that underlie genetic architecture and phenotypic variation complex traits, not only in humans, but also livestock animals. We identified CNVs along the chicken genome analyzed their association with performance traits. Genome-wide were inferred from Affymetrix® high density SNP-chip data for broiler population. concatenated into segments analyses performed linear mixed models considering...

Service sire has been recognized as an important factor affecting dairy herd fertility. Our group reported promising results on gene mapping and genomic prediction of bull fertility using autosomal SNP markers. Little is known, however, about the genetic contribution sex chromosomes, which are enriched in genes related to sexual development reproduction. As such, main goal this study was investigate effect markers X Y chromosomes (BTAX BTAY, respectively) conception rate (SCR) US Holstein...

We analyzed single nucleotide polymorphisms in calpain, leptin, leptin receptor, and growth hormone receptor genes their association with color, drip cooking losses of longissimus muscle at 7, 14 21 days postmortem 638 purebred Nellore bulls slaughtered between 22 26 months age.Meat samples were vacuum-packed aged 4°C.The T945M, GHR2, E2FB, CAPN4751 evaluated.All genotypic classes observed; however, the T/T genotype T945M E2FB was found a low frequency.A significant loss (a measure...

We looked for possible associations of SNPs in genes related to protein turnover, with growth, feed efficiency and carcass traits feedlot Nellore cattle.Purebred bulls steers (N = 290; 378 ± 42 kg body weight, 23 months days old) were evaluated daily intake, weight gain (BWG), gross efficiency, conversion ratio, partial residual intake (RFI), ultrasound backfat, rump fat, ribeye area.Genotypes obtained the growth hormone receptor (GHR-1 GHR-2); calpain (CAPN4751); calpastatin (UoGCAST);...

The association between two single nucleotide polymorphisms (SNPs), T945M and UCP1SNP1, with hot carcass weight (HCW, kg, N = 618), longissimus dorsi muscle area (REA, cm(2), 633), backfat thickness (BF, mm, 625), measured in Nellore cattle Brazil, was evaluated. Likelihood ratio tests were used to evaluate reduced (fixed effects of general mean, contemporary group, yearling weight, age at slaughter, random effect infinitesimal genetic value) full model (reduced plus quantitative trait locus...

Structural equation models involving latent variables are useful tools for formulating hypothesized defined by theoretical and causal links between these variables. The objectives of this study were: (1) to identify underlying carcass meat quality traits (2) perform whole-genome scans in order genomic regions individual genes with both direct indirect effects. A total 726 steers from an Angus-Brahman multibreed population records 22 phenotypes were used. 480 animals genotyped the GGP Bovine...

The present study aimed to estimate covariance components of milk fatty acids (FA) and compare the genomic estimated breeding values under general heat-stress effects. Data consisted 38,762 test-day records from 6,344 Holstein cows obtained May 2012 through January 2018 on 4 dairy herds Brazil. Single-trait repeatability models with random regressions as a function temperature-humidity index were used for genetic analyses. included contemporary groups, parity order (1-6), days in classes...

Given the important role of leptin in metabolism, we looked for a possible association and receptor polymorphisms with carcass growth traits Nellore cattle. We examined associations SNPs ultrasound (longissimus dorsi muscle area (ribeye area), backfat thickness rump fat (weaning weight adjusted to 210 days age, yearling 550 gain weaning scrotal circumference age) 2162 Bos primigenius indicus (Nellore) animals. Allele genotypic frequencies were calculated each marker. substitution, additive...

Tenderness is a major quality attribute for fresh beef steaks in the United States, and meat traits general are suitable candidates genomic research. The objectives of present analysis were to (1) perform genome-wide association (GWA) marbling, Warner-Bratzler shear force (WBSF), tenderness, connective tissue using whole-genome data an Angus population, (2) identify enriched pathways each GWA analysis; (3) construct protein-protein interaction network associated genes (4) μ-calpain...

Meat quality of Nellore bulls provide important advances in carcass traits and meat breeding programs cattle that are raised tropical conditions.

Many studies have explored variability to select cattle with high genetic potential for economic interest traits.Genetic is a powerful tool improve production indexes in cattle, as it also associated variations meat and carcass quality traits.We made Genome-Wide Association Study of beef Bos indicus origin, particular Nelore animals, identify regions genes quality, by examining phenotypic genotypic data from 909 animals.Several were observed above 1% the portion explained variance explained:...

Breast weight has great economic importance in poultry industry, and may be associated with other variables. This work aimed to estimate phenotypic correlations between performance (live body at 7 28 days, slaughter, depth of the breast muscle measured by ultrasonography), carcass (eviscerated leg weight) composition (heart, liver abdominal fat traits a broiler line, quantify direct indirect influence these on weight. Path analysis was used expanding matrix partial correlation coefficients...

The use of information across populations is an attractive approach to increase the accuracy genomic predictions for numerically small breeds and traits that are time-consuming difficult measure, such as male fertility in cattle. This study was conducted evaluate prediction Jersey bull using across-country reference population combining records from United States Australia. data set consisted 1,570 US bulls with sire conception rate (SCR) records, 603 Australian semen value (SFV) SNP...

Abstract Background Carcass weight (HCW) and marbling (MARB) are critical for meat quality market value in beef cattle. In composite breeds like Brangus, which meld the genetics of Angus Brahman, SNP-based analyses have illuminated some genetic influences on these traits, but they fall short fully capturing nuanced effects breed origin alleles (BOA) traits. Focus impacts BOA phenotypic features within Brangus populations can result a more profound understanding specific Brahman genetics....

A data set of a commercial Nellore beef cattle selection program was used to compare breeding models that assumed or not markers effects estimate the values, when reduced number animals have phenotypic, genotypic and pedigree information available. This herd complete composed 83,404 measured for weaning weight (WW), post-weaning gain (PWG), scrotal circumference (SC) muscle score (MS), corresponding 116,652 in relationship matrix. Single trait analyses were performed by MTDFREML software...