A5034157163- Genetic and phenotypic traits in livestock
- Animal Nutrition and Physiology
- Livestock and Poultry Management
- Vector-borne infectious diseases
- Animal Genetics and Reproduction
- Vector-Borne Animal Diseases
- Helminth infection and control
- Cancer-related molecular mechanisms research
- Meat and Animal Product Quality
- Genetic Mapping and Diversity in Plants and Animals
- Insect symbiosis and bacterial influences
- Animal Virus Infections Studies
- Molecular Biology Techniques and Applications
- Effects of Environmental Stressors on Livestock
- RNA modifications and cancer
- Peroxisome Proliferator-Activated Receptors
- RNA Research and Splicing
- Muscle Physiology and Disorders
- Microbial infections and disease research
- Wastewater Treatment and Nitrogen Removal
- Virus-based gene therapy research
- Orthopedic Infections and Treatments
- Congenital Anomalies and Fetal Surgery
- Genetics, Aging, and Longevity in Model Organisms
- Animal Disease Management and Epidemiology
Brazilian Agricultural Research Corporation
2013-2024
Universidade Estadual do Centro-Oeste
2020-2024
Concordia University Wisconsin
2013-2024
Universidade do Contestado
2018
Universidade Federal de São Carlos
2008-2016
Texas A&M University
2012-2014
Abstract Background The integration of molecular data from hosts, parasites, and microbiota can enhance our understanding the complex biological interactions underlying resistance hosts to parasites. Haemonchus contortus , predominant sheep gastrointestinal parasite species in tropics, causes significant production economic losses, which are further compounded by diminishing efficiency chemical control owing anthelmintic resistance. Knowledge how host responds infection parasite, combination...
This study evaluated the resistance of cattle different genetic groups to tick Rhipicephalus microplus and relationship with traits animals' hair coat. Cows Senepol×Nelore (SN), Angus×Nelore (AN) Nelore (NX) were submitted four consecutive artificial infestations, at 14-day intervals, each one approximately 20,000 larvae placed on lumbar region. From 19th 23rd day infestation five counts number ticks performed animal's left body side. The count data (TTC) transformed into log(10) (n+1), also...
Abstract We previously demonstrated that A mblyomma americanum tick serine protease inhibitor 6 ( Aam S6 ) was secreted into the host during feeding and both its m RNA protein were ubiquitously highly expressed first 3 days of feeding. This study demonstrates am S is a cross‐class serine‐ papain‐like cysteine proteases has apparent antihaemostatic functions. Consistent with typical inhibitory serpin characteristics, enzyme kinetics analyses revealed P ichia pastoris‐ recombinant (r) reduced...
White striping (WS) is one of the most common myopathies identified in broiler chickens leading to substantial production losses, where incidence reaches 12% commercial chickens. It occurs primarily heavier being a modification breast muscle characterized by presence pale parallel streaks same orientation fibers. Since WS etiology remains unclear, we aimed identify biological and genetic mechanisms involved its occurrence through whole transcriptome analysis affected unaffected chicken...
Natural and artificial selection leads to changes in certain regions of the genome resulting signatures that can reveal genes associated with selected traits. Selection may be identified using different methodologies, which some are based on detecting contiguous sequences homozygous identical-by-descent haplotypes, called runs homozygosity (ROH), or estimating fixation index (FST) genomic windows indicates genetic differentiation. This study aimed identify a paternal broiler TT line at...
Abstract Background Copy number variations (CNVs) are a major type of structural genomic variants that underlie genetic architecture and phenotypic variation complex traits, not only in humans, but also livestock animals. We identified CNVs along the chicken genome analyzed their association with performance traits. Genome-wide were inferred from Affymetrix® high density SNP-chip data for broiler population. concatenated into segments analyses performed linear mixed models considering...
Chicken feed efficiency (FE) traits are the most important economic in broiler production. Several studies evaluating genetic factors affecting food consumption chickens available. However, of these identified genomic regions containing putative quantitative trait loci for each separately. It is still a challenge to find common gene networks related traits. Therefore, here, genome-wide association study (GWAS) was conducted explore candidate responsible Feed Intake (FI), Body Weight Gain...
The objective of the current investigation was to evaluate several Eimeria challenges and resulting alterations in intestinal permeability, morphology, lesion scores broiler chickens. This study included four groups with ten replicate cages per treatment, which each group received a different treatment dosage Eimeria, characterizing high, medium-high, medium-low challenges. Five days after challenge, lesions permeability were assessed. results showed that increase challenge led considerable...
Genomic regions under high selective pressure present specific runs of homozygosity (ROH), which provide valuable information on the genetic mechanisms underlying adaptation to environment imposed challenges. In broiler chickens, conventional production systems in tropical environments lead animals with favorable genotypes be naturally selected, increasing frequency these alleles next generations. this study, ~1400 chickens from a paternal line were genotyped 600 K Affymetrix® Axiom®...
This study investigated the interactions between naturally occurring bacteria and microalgae Chlorella vulgaris within a lab scale photobioreactor treating ammonia-rich swine wastewater digestate effluent. Nitrification denitrification were assessed by targeting ammonia monoxygenases (amoA), nitrate (narG), nitrite (nirS), nitric oxide (norB) nitrous (nosZ) reductases genes. Oxygen produced from photosynthesis stimulated nitrification. Under limiting carbon availability (i.e., <1.44 for mg...
Excess fat content in chickens has a negative impact on poultry production. The discovery of QTL associated with deposition the carcass allows identification positional candidate genes (PCGs) that might regulate and be useful for selection against excess chicken's carcass. This study aimed to estimate genomic heritability coefficients identify QTLs PCGs abdominal (ABF) skin (SKIN) traits broiler chicken population, originated from White Plymouth Rock Cornish breeds. ABF SKIN are moderately...
Genetic resistance in cattle is considered a suitable way to control tick burden and its consequent losses for livestock production. Exploring tick-resistant (R) tick-susceptible (S) hosts, we investigated the genetic mechanisms underlying variation of Braford infestation. Skin biopsies from four-times-artificially infested R (n = 20) S 19) obtained before first 24 h after fourth infestation were submitted RNA-Sequencing. Differential gene expression, functional enrichment, network analysis...
Production animals are constantly subjected to early adverse environmental conditions that influence the adult phenotype and produce epigenetic effects. CpG dinucleotide methylation in red blood cells (RBC) could be a useful biomarker identify chronic stress production environment. Here we compared reduced fraction of RBC methylome chickens exposed social isolation non-exposed. These experiments were performed two different locations: Brazil Sweden. The aim was stress-associated DNA profiles...
Among the gastrointestinal nematodes affecting sheep, Haemonchus contortus is most prevalent and virulent, resulting in health problems production losses. Therefore, selecting sheep resistant to H. a suitable sustainable strategy for controlling endoparasites flocks. Here, 287 lambs of native Brazilian Morada Nova hair breed were subjected two consecutive artificial infections with assessed fecal egg count (FEC), packed cell volume (PCV), live weight (LW). Forty-four animals ranked as having...
Abstract Introduction White Striping (WS) and Wooden Breast (WB) pectoral myopathies are relevant disorders for contemporary broiler production worldwide. Several studies aimed to elucidate the genetic components associated with occurrence of these myopathies. However, epigenetic factors that trigger or differentiate two conditions still unclear. The aim this study was identify miRNAs differentially expressed (DE) between normal WS WB-affected broilers, verify possible role in metabolic...
Ca and P homeostasis across the egg-laying cycle is a complex process involving absorption in small intestine, reabsorption/excretion kidneys, eggshell gland secretion. Diets with inadequate calcium phosphorus can interfere their digestibility, resulting quality losses reduced productive life, affecting egg production welfare. A better understanding of gene expression profiles kidneys laying hens during late period could clarify renal role mineral metabolism at this stage. Therefore,...
Genetic differences in susceptibility to ticks (Rhipicephalus (Boophilus) microplus) are considerable bovines. Here, mapping, association and gene expression approaches were employed further advance our understanding of the molecular basis tick resistance. A B. taurus x indicus F2 population was developed by Embrapa 382 individuals measured for parasitic load. Scanning all chromosomes is progress. Quantitative trait loci (QTL) load mapped 4, 5, 7, 10, 14, 18 23 out 20 scanned dependent on...