A5050790593- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Cancer-related molecular mechanisms research
- Vector-borne infectious diseases
- Gene expression and cancer classification
- Vector-Borne Animal Diseases
- Agricultural Productivity and Crop Improvement
- Genetics and Plant Breeding
- Evolutionary Algorithms and Applications
- Animal Nutrition and Health
- Meat and Animal Product Quality
- Animal Genetics and Reproduction
- Helminth infection and control
- Genetic diversity and population structure
- Molecular Biology Techniques and Applications
- Viral Infections and Vectors
- Reproductive Physiology in Livestock
- Genetic Associations and Epidemiology
- Genomics and Phylogenetic Studies
- Livestock Farming and Management
- Metaheuristic Optimization Algorithms Research
- Muscle Physiology and Disorders
- Livestock Management and Performance Improvement
- Animal Nutrition and Physiology
- Reproductive Biology and Fertility
Michigan State University
2017-2024
Michigan United
2024
Louisiana State University System
2023
Munster Technological University
2023
Commonwealth Scientific and Industrial Research Organisation
2018-2021
Utrecht University
2018-2021
Northeast Agricultural University
2018-2021
Universidade Estadual Paulista (Unesp)
2020-2021
Roslin Institute
2018-2021
Research Institute for Farm Animal Biology (FBN)
2018-2021
Feed efficiency is an economically important trait in beef production. It can be measured as residual feed intake. This the difference between actual intake recorded over a test period and expected of animal based on its size growth rate. DNA-based marker-assisted selection would help breeders to accelerate genetic improvement for by reducing generation interval obviate high cost measuring Although numbers quantitative loci candidate genes have been identified with advance molecular...
Body weight (BW) is an important trait for meat production in sheep. Although over the past few years, numerous quantitative loci (QTL) have been detected traits cattle, QTL studies reported sheep, with even fewer on traits. Our objective was to perform a genome-wide association study (GWAS) medium-density Illumina Ovine SNP50 BeadChip identify genomic regions and corresponding haplotypes associated BW Australian Merino sheep.A total of 1781 sheep were genotyped using BeadChip. Among 53 862...
Natural selection has molded evolution across all taxa. At an arguable date of around 330,000 years ago there were already at least two different types cattle that became ancestors nearly modern cattle, the Bos taurus more adapted to temperate climates and tropically indicus. After domestication, human exponentially intensified these differences. To better understand genetic differences between subspecies detect genomic regions potentially under divergent selection, animals from...
Background The Prevalence and persistence of ADHD have not been described in young Australian adults few studies examined how conduct problems (CP) are associated with for this age group. We estimate lifetime adult prevalence rates three categories 3795 adults, indicate career, health childhood risk factors differ people symptoms plus CP. Methodology Trained interviewers collected participant experience ADHD, CP, education, employment, experience, relationship variables. Three diagnostic...
Knowledge of the genetic structure and overall diversity livestock species is important to maximise potential genome-wide association studies genomic prediction. Commonly used measures such as linkage disequilibrium (LD), effective population size (N e ), heterozygosity, fixation index (F ST) runs homozygosity (ROH) are widely help improve our knowledge about in animal populations. The development high-density single nucleotide polymorphism (SNP) arrays subsequent genotyping large numbers...
Abstract Genetic mapping to identify genes and alleles associated with or causing economically important quantitative trait variation in livestock animals such as pigs is a major goal animal genetic improvement. Despite recent advances high-throughput genotyping technologies, the resolution of remains poor due part low density genotyped variant sites. In this study, we overcame limitation by developing reference haplotype panel for based on 2259 whole genome-sequenced representing 44 pig...
ABSTRACT The cattle tick, Rhipicephalus ( Boophilus ) microplus , is a major threat to the improvement of production in tropical and subtropical countries worldwide. Bos indicus are naturally more resistant infestation with tick than taurus breeds, although considerable variation resistance occurs within between breeds. It not known which genes contribute phenotype, nor have immune parameters involved R. been fully described for bovine host. This study was undertaken determine whether...
This genome-wide association study (GWAS) was conducted to identify major loci that are significantly associated with carcass weight, and their effects, in order provide increased understanding of the genetic architecture weight Hanwoo. identified one chromosome region ranging from 23 Mb 25 on 14 as being Significant Bonferroni-corrected associations (P<1.52×10−6) were detected for 6 Single Nucleotide Polymorphic (SNP) 14. The most significant SNP BTB-01280026 (P = 4.02×10−11), located Bos...
This study aimed at identifying genomic regions that underlie genetic variation of worm egg count, as an indicator trait for parasite resistance in a large population Australian sheep, which was genotyped with the high-density 600 K Ovine single nucleotide polymorphism array. included 7539 sheep from different locations across Australia underwent field challenge mixed gastrointestinal species. Faecal samples were collected and counts three strongyle species, i.e. Teladorsagia circumcincta,...
Abstract Background The integration of molecular data from hosts, parasites, and microbiota can enhance our understanding the complex biological interactions underlying resistance hosts to parasites. Haemonchus contortus , predominant sheep gastrointestinal parasite species in tropics, causes significant production economic losses, which are further compounded by diminishing efficiency chemical control owing anthelmintic resistance. Knowledge how host responds infection parasite, combination...
Abstract Background Genetic merit, or breeding values as referred to in livestock and crop programs, is one of the keys successful selection animals commercial farming systems. The developments statistical methods during twentieth century single nucleotide polymorphism (SNP) chip technologies twenty-first have revolutionized agricultural production, by allowing highly accurate predictions for candidates at a very early age. Nonetheless, many populations, realized accuracies predicted (PBV)...
Summary Reliability of parentage test panels is usually based on its power to exclude wrong assignments allele frequencies. We evaluated the rates false exclusions and inclusions in assignments, how these results are affected by frequencies, panel sizes number allowed mismatches. also reliability testing comparing populations with distinct genetic backgrounds using pure composite families cattle sheep. Allowing for 1% genotype mismatches true parent–offspring relations provided best...
Circadian rhythms and metabolism are tightly integrated, rhythmic expression of metabolic factors is common in homeostatic processes. We measured the temporal changes myogenic regulatory activity level molecules involved protein skeletal muscles livers mice examined impact fasting. Tissues were collected over 24 h (at zeitgeber times ZT1, ZT5, ZT9, ZT13, ZT17, ZT21, ZT1 following day) from adult male C57Bl/6J that had been either freely fed or fasted for h. In muscle, there was a robust rise...
This paper presents results from a mapping experiment to detect quantitative trait loci (QTL) for resistance Haemonchus contortus infestation in merino sheep. The primary analysed was faecal worm egg count response artificial challenge at 6 months of age. In the first stage experiment, whole genome linkage analysis used broad-scale mapping. animal resource designed flock comprising 571 individuals four half-sib families. average marker spacing about 20 cM. For trait, 11 QTL (as...
Marbling (intramuscular fat) is a valuable trait that impacts on meat quality and an important factor determining price of beef in the Korean market. Animals are destined for this high marbling market fed concentrate ration approximately 30 months finishing farms. However, feeding strategy leads to inefficiencies excessive fat production. This study aimed identify candidate genes pathways associated with intramuscular deposition highly divergent phenotypes adult Hanwoo cattle.Bovine genome...
When the effects of heat stress are detrimental during maturation, cumulus cells intimately associated with oocyte. To determine extent to which affects these cells, in this study, transcriptome profiles that surrounded control and heat-stressed oocytes (41 °C first 12 h only then shifted back 38.5 °C) vitro maturation (IVM) were compared using Affymetrix bovine microarrays. The comparison cumulus-derived revealed a number transcripts whose levels increased ( n =11) or decreased =13) ≥...
The objective of this study was to perform a genomewide association (GWAS) for growth traits in Charolais beef cattle and identify SNP markers genes associated with these traits. Our included 855 animals genotyped using 76,883 from the GeneSeek Genomic Profiler Bovine HD panel. examined phenotypic data birth, weaning, yearling weights as well pre- postweaning ADG. After quality control, 68,337 823 were retained analysis. analysis performed principal components method via egscore function...
Quantitative traits are usually controlled by numerous genomic variants with small individual effects, and variances associated those explained in a continuous manner. However, the relative contributions of regions to observed genetic variations have not been well explored using sequence level SNP information. Here, imputed data (11,278,153 SNPs) 2109 Hanwoo steers (Korean native cattle) were partitioned according functional annotation, chromosome, minor allele frequency (MAF). Genomic...