A5024789097- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Cancer-related molecular mechanisms research
- Genetics and Plant Breeding
- Animal Nutrition and Physiology
- Meat and Animal Product Quality
- Metabolomics and Mass Spectrometry Studies
- Wireless Power Transfer Systems
- Gut microbiota and health
- Genetic Associations and Epidemiology
- Animal Behavior and Welfare Studies
- Genomic variations and chromosomal abnormalities
- Remote Sensing and Land Use
- Multilevel Inverters and Converters
- Model Reduction and Neural Networks
- Remote Sensing and LiDAR Applications
- Ginseng Biological Effects and Applications
- Advanced DC-DC Converters
- Optical Wireless Communication Technologies
- Animal Genetics and Reproduction
- Energy Harvesting in Wireless Networks
- Advanced Proteomics Techniques and Applications
- Optimal Power Flow Distribution
- Probabilistic and Robust Engineering Design
- Adipose Tissue and Metabolism
South China Agricultural University
2017-2024
Nanjing University of Aeronautics and Astronautics
2024
Key Laboratory of Guangdong Province
2021-2024
Poultry Research Institute
2024
Michigan State University
2022-2024
Northwest A&F University
2024
Wen's Food Group (China)
2021-2022
Yanshan University
2014
Increasing feed efficiency is a major goal of breeders as it can reduce production cost and energy consumption. However, the genetic architecture feeding behavior traits remains elusive. To investigate in pigs, three (daily intake, number daily visits to feeder, duration each visit) two (feed conversion ratio residual intake) were considered. We performed genome-wide association studies (GWASs) five using population 1,008 Duroc pigs genotyped with an Illumina Porcine SNP50K BeadChip. A total...
Abstract Genetic mapping to identify genes and alleles associated with or causing economically important quantitative trait variation in livestock animals such as pigs is a major goal animal genetic improvement. Despite recent advances high-throughput genotyping technologies, the resolution of remains poor due part low density genotyped variant sites. In this study, we overcame limitation by developing reference haplotype panel for based on 2259 whole genome-sequenced representing 44 pig...
Intramuscular fat (IMF) is an important meat trait relevant to the processing industry and consumer acceptance. To gain a better understanding of genetic determinants IMF, we used composite strategy, including single-locus multi-locus association analyses perform genome-wide studies (GWAS) for IMF in 1,490 Duroc boars. We estimated genomic heritability be 0.23 ± 0.04. A total 30 SNPs were detected as significantly associated with IMF. Of these, five, nine, eight, 21 significant identified by...
Abstract Background More teats are necessary for sows to nurse larger litters provide immunity and nutrient piglets prior weaning. Previous studies have reported the strong effect of an insertion mutation in Vertebrae Development Associated ( VRTN ) gene on Sus scrofa chromosome 7 (SSC7) that increased number thoracic vertebrae teat pigs. We used genome-wide association (GWAS) map genetic markers genes associated with two Duroc pig populations different backgrounds. A single marker method...
Growth traits are important economic of pigs that controlled by several major genes and multiple minor genes. To better understand the genetic architecture growth traits, we performed a weighted single-step genome-wide association study (wssGWAS) to identify genomic regions candidate associated with days 100 kg (AGE), average daily gain (ADG), backfat thickness (BF) lean meat percentage (LMP) in Duroc pig population. In this study, 3945 individuals phenotypic genealogical information, which...
Abstract Background In the process of pig breeding, average daily gain (ADG), days to 100 kg (AGE), and backfat thickness (BFT) are directly related growth rate fatness. However, genetic mechanisms involved not well understood. Copy number variation (CNV), an important source diversity, can affect a variety complex traits diseases has gradually been thrust into limelight. this study, we reported genome-wide CNVs Duroc pigs using SNP genotyping data from 6627 animals. We also performed copy...
Backfat thickness (BFT) is complex and economically important traits in the pig industry, since it reflects fat deposition can be used to measure carcass lean meat percentage pigs. In this study, all 6,550 pigs were genotyped using Geneseek Porcine 50K SNP Chip identify SNPs related BFT search for candidate genes through genome-wide association analysis two Duroc populations. total, 80 SNPs, including 39 significant 41 suggestive 6 QTLs identified significantly associated with BFT. addition,...
Human mediated intra-continental exchange of genetic material among domesticated organisms has never been restricted to a single direction. The introduction pig breeds between China and Europe aims enhance economically important traits in local populations. However, the reciprocal introgression pattern, specifically role introgressed genes structural variations (SVs), remains underexplored. A global collection whole-genome resequencing data is utilized from 418 pigs generate comprehensive...
Efficient use of feed resources is a challenge in the pork industry because largest variability expenditure attributed to cost fodder. Efficiency feeding directly related behavior. In order identify genomic regions controlling behavior and eating efficiency traits, 338 Duroc boars were used this study. The Illumina Porcine SNP60K BeadChip was for genotyping. Data pertaining individual daily intake (DFI), total time spent feeder (TPD), number visits (NVD), average duration each visit (TPV),...
The Duroc × (Landrace Yorkshire) hybrid pigs (DLY) are the most popular commercial pigs, providing consumers with largest source of pork. In order to gain more insights into genetic architecture economically important traits in we performed a genome-wide association study (GWAS) using GeneSeek Porcine 50 K SNP Chip map markers and genes associated body conformation (BCT) 311 DLY pigs. quantitative analyzed included weight (BW), carcass length (CL), (BL), height (BH), mass index (BMI). BMI...
Abstract Background Carcass traits are important in pig breeding programs for improving pork production. Understanding the genetic variants underlies complex phenotypes can help explain trait variation pigs. In this study, we integrated a weighted single-step genome-wide association study (wssGWAS) and copy number (CNV) analyses to map variations genes associated with loin muscle area (LMA), depth (LMD) lean meat percentage (LMP) Duroc Results Firstly, performed analysis CNV detection using...
Duroc pigs are famous for their high growth rate, feed conversion efficiency, and lean meat percentage. Given that they have been subjected to artificial selection breeding in multiple countries, various lines with obvious differences production performance formed. In this study, we genotyped 3,770 American (AD) 2,098 Canadian (CD) using the GeneSeek Porcine SNP50 Beadchip dissect genetic potential genes of traits these two pig lines. Population structure detection showed there were...
Heterozygosity can effectively reflect the diverse models of population structure and demographic history. However, genomic distribution heterozygotes correlation between regions heterozygosity (runs heterozygosity, ROHet) phenotypes are largely understudied in livestock. The objective this study was to identify ROHet Duroc pig genome, investigate relationships eight important economic traits. Here, we genotyped 3,770 American (S21) 2,096 Canadian (S22) pigs using 50 K single nucleotide...
Runs of homozygosity (ROH) are widely used to investigate genetic diversity, demographic history, and positive selection signatures livestock. Commercial breeds provide excellent materials reveal the landscape ROH shaped during intense process. Here, we GeneSeek Porcine 50K single-nucleotide polymorphism (SNP) Chip data 3,770 American Duroc (AD) 2,096 Canadian (CD) pigs analyze genome-wide ROH. First, showed that AD had a moderate differentiation with CD pigs, more abundant diversity...
Abstract Background Improving feed efficiency is economically and environmentally beneficial in the pig industry. A deeper understanding of essential on many levels for its highly complex nature. The aim this project to explore relationship between fecal metabolites efficiency-related traits, thereby identifying that may assist screening pigs. Results We performed metabolomics analysis 50 individuals selected from 225 Duroc x (Landrace Yorkshire) (DLY) commercial pigs, 25 with an extremely...
Objective Average daily gain (ADG) is an important target trait of pig breeding programs. We aimed to identify single nucleotide polymorphisms (SNPs) and genomic regions that are associated with ADG in the Duroc population. Methods performed a genome-wide association study involving 390 boars by using PorcineSNP60K Beadchip two linear models. Results After quality control, we detected 3,5971 SNPs, which included seven SNPs significantly pigs. identified six quantitative loci (QTL) for ADG....
Abstract Feed efficiency (FE) is an important trait in the porcine industry. Therefore, understanding molecular mechanisms of FE vital for improvement this trait. In study, 6 extreme high-FE and low-FE pigs were selected from 225 Duroc × (Landrace Yorkshire) (DLY) transcriptomic analysis. RNA-seq analysis was performed to determine differentially expressed genes (DEGs) liver tissues 12 individuals, 507 DEGs identified between (HE- group) (LE- group). A gene ontology (GO) enrichment pathway...
Chest circumference (CC), abdominal (AC), and waist (WC) are regarded as important indicators for improving economic traits because they can reflect the growth physiological status in pigs. However, genetic architecture of CC, AC, WC is still elusive. Here, we performed single-trait multi-trait genome-wide association studies (GWASs) 2,206 American origin Duroc (AOD) 2,082 Canadian (COD) As a result, one novel quantitative trait locus (QTL) on Sus scrofa chromosome (SSC) was associated with...
The development of a comprehensive pig graph pangenome assembly encompassing 27 genomes represents the most extensive collection genomic data to date. Analysis this reveals critical role structural variations in driving adaptation and defining breed-specific traits. Notably, study identifies BTF3 as key candidate gene governing intramuscular fat deposition meat quality pigs. These findings underscore power approaches uncovering novel features underlying economically important agricultural...
Feed cost accounts for approximately 65–75% of overall commercial pork production costs. Therefore, improving the feed efficiency pig is important. In this study, 12 individuals with either extremely high (HE) or low (LE) were selected from 225 Duroc × (Landrace Yorkshire) (DLY) pigs. After pigs slaughtered, we collected small intestine mucosal tissue. Next, RNA sequencing (RNA-seq) analysis was used to reveal presence and quantity genes expressed between these HE- LE-groups. We found 433...
Abstract Background Pork quality can directly affect customer purchase tendency and meat traits have become valuable in modern pork production. However, genetic improvement has been slow due to high phenotyping costs. In this study, whole genome sequence (WGS) data was used evaluate the prediction accuracy of genomic best linear unbiased (GBLUP) for large-scale crossbred commercial pigs. Results We produced WGS (18,695,907 SNPs 2,106,902 INDELs exceed control) from 1,469 sequenced Duroc ×...
During the process of pork production, carcasses pigs are divided and sold, which provides better economic benefits market competitiveness for production than selling carcass as a whole. Due to significant cost post-slaughter phenotypic measurement, genetic architecture tenderloin weight (TLNW) rib (RIBW)—important components pig value—remain unknown. In this study, we conducted genome-wide association studies (GWAS) TLNW RIBW traits in population 431 Duroc × Landrace Yorkshire (DLY) pigs....