A5004880396- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Animal Behavior and Welfare Studies
- Genetic diversity and population structure
- Cancer-related molecular mechanisms research
- Animal Nutrition and Physiology
- Wildlife Ecology and Conservation
- Animal Genetics and Reproduction
- Plant and animal studies
- Rangeland Management and Livestock Ecology
- Livestock Farming and Management
- Insect Utilization and Effects
- Meat and Animal Product Quality
- Primate Behavior and Ecology
- Animal Behavior and Reproduction
- Muscle Physiology and Disorders
- Gut microbiota and health
- Genomics and Chromatin Dynamics
- Physiological and biochemical adaptations
- Livestock and Poultry Management
- Surgical Sutures and Adhesives
- Telomeres, Telomerase, and Senescence
- Aquaculture Nutrition and Growth
- Genomics and Phylogenetic Studies
- Botanical Studies and Applications
South China Agricultural University
2023-2025
Poultry Research Institute
2023-2025
Wageningen University & Research
2019-2022
Ludwig-Maximilians-Universität München
2022
China Agricultural University
2017-2021
National Laboratory for Civil Engineering
2017-2021
Ministère de l'Agriculture et de la Souveraineté alimentaire
2017-2021
Abstract Hybrid mapping is a powerful approach to efficiently identify and characterize genes regulated through mechanisms in cis. In this study, using reciprocal crosses of the phenotypically divergent Duroc Lulai pig breeds, we perform comprehensive multi-omic characterization regulatory variation across brain, liver, muscle, placenta four developmental stages. We produce one largest datasets pigs date, including 16 whole genome sequenced individuals, as well 48 bisulfite sequencing, 168...
Abstract Wild boar ( Sus scrofa ) drastically colonized mainland Eurasia and North Africa, most likely from East Asia during the Plio-Pleistocene (2–1Mya). In recent studies, based on genome-wide information, it was hypothesized that wild did not replace species encountered, but instead exchanged genetic materials with them through admixture. The highly endangered pygmy hog Porcula salvania) is only suid in known to have outlived this expansion, therefore provides a unique opportunity test...
It is widely accepted that modern pigs were domesticated independently at least twice, and Chinese native are deemed as direct descendants of the first in corresponding domestication centers. By analyzing mitochondrial DNA sequences an extensive sample set spanning 10,000 years, we find earliest from middle Yellow River region already carried maternal lineages dominant both younger archaeological populations pigs. Our data also supports early Neolithic pig utilization a long-term situ origin...
It has been long demonstrated that cage rearing (CR) deprives the animal of possibility to express natural behaviors and results in stress. However, effect system on gene expression molecular levels gut microbiome are unknown. 10-wk-old Beijing You chickens were studied parallel CR free-range (FR) systems for 30 wk, investigate behavior, microbiota composition, expression. From week 40, a match-mismatch design was conducted 5 wk. The indicated animals behaviors, evidenced by sham...
Abstract Increasing human disturbance and climate change have a major impact on habitat integrity size, with far‐reaching consequences for wild fauna flora. Specifically, population decline fragmentation result in small, isolated populations. To what extend different endangered species can cope small size is still largely unknown. Studies the genomic landscape of these shed light past demographic dynamics current genetic load, thereby also providing guidance conservation programs. The pygmy...
Tilapia is a group of originally fresh water species, some which can be tolerate wide range salinities and cultured in estuaries or brackish ponds polyculture with shrimp. Although the physiological processes that underly osmoregulation have been studied extensively, it less clear how artificial selection produce adaptation to salinity stress. Here we genomic architecture an Indonesian saline-tolerant strain, called "Sukamandi", was selected for rapid growth water. We also investigated...
The composition of muscle fibers, characterized by distinct contractile and metabolic properties, significantly influences meat quality glucose homeostasis. However, the mechanisms which three-dimensional (3D) genome topology integrates with epigenetic states to regulate fiber specification transformation remain poorly understood. Here, we present an integrative analysis transcriptome, epigenome, 3D architecture in slow-twitch glycolytic extensor digitorum longus (EDL) fast-twitch oxidative...
Genomic prediction (GP), which uses genome-wide markers to estimate breeding values, is a crucial tool for accelerating genetic progress in livestock and plant breeding. The accuracy of GP depends on several factors, including the statistical model, marker density, cross-validation strategy. This study evaluated these factors optimize eight economically important carcass body traits Duroc × (Landrace Yorkshire) (DLY) pig population. used 50 K SNP chip data from 1494 DLY pigs, were imputed...
Human mediated intra-continental exchange of genetic material among domesticated organisms has never been restricted to a single direction. The introduction pig breeds between China and Europe aims enhance economically important traits in local populations. However, the reciprocal introgression pattern, specifically role introgressed genes structural variations (SVs), remains underexplored. A global collection whole-genome resequencing data is utilized from 418 pigs generate comprehensive...
Congenital developmental abnormalities in piglets, such as intersex and aproctia, adversely affect survival rates, growth performance, genetic breeding efficiency pig populations. To elucidate their basis, we performed a genome-wide association study (GWAS) on 1030 Large White pigs. We combined 50 K SNP chip data with SWIM-based genotype imputation to enhance the resolution of variation detection, followed by MLM analysis. Our results identified 53 significant SNPs, 52 associated 1 aproctia....
Poultry welfare has been extensively studied; however, there is a lack of rigorous scientific knowledge relating to the different aspects factors and how this may contribute production quantity product quality as well chickens. Therefore, we conducted an integrated study compare in chickens by providing free dietary choice under cage rearing, further comparing rearing with free-range rearing. One hundred each were allocated group conventional feeding (CC), mealworms (FDM), fresh grass...
In bovine species, mitochondrial DNA polymorphisms and their correlation to productive or reproductive performances have been widely reported across breeds individuals. However, experimental evidence of this has never provided. order identify differences among mtDNA haplotypes, transmitochondrial cybrids were generated, with the nucleus from MAC-T cell line, derived a Holstein dairy cow (Bos taurus) mitochondria either primary line domestic Chinese native beef Luxi cattle breed central Asian...
The growth of animals is a complex trait, in chicken resulting diverse variety forms, caused by heterogeneous genetic basis. Bantam chicken, known as an exquisite form dwarfism, has been used for crossbreeding to create corresponding dwarf counterparts native fowls the Dutch populations. Here, we demonstrate heterogeneity bantam trait chickens and reveal underlying causes, using whole-genome sequence data from matching pairs normal-sized breeds. During bantam-oriented crossbreeding, various...
Enhancing the accuracy of genomic prediction is a key goal in selection (GS) research. Integrating prior biological information into GS methods using appropriate models can improve for complex traits. Genome-wide association study (GWAS) widely utilized to identify potential candidate loci associated with traits livestock and poultry, offering essential insights. In this study, GWAS was conducted on 685 Duroc × Landrace Yorkshire (DLY) pigs extract significant single-nucleotide polymorphisms...
It is largely unknown how mammalian genomes evolve under rapid speciation and environmental adaptation. An excellent model for understanding fast evolution provided by the genus Sus, which diverged relatively recently lacks postzygotic isolation. Here, we present a high-quality reference genome of Visayan warty pig, specialized to tropical island environment. Comparing sequences chromatin contact maps pig (Sus cebifrons) domestic scrofa), characterized dynamics chromosomal structure during...
During the process of pork production, carcasses pigs are divided and sold, which provides better economic benefits market competitiveness for production than selling carcass as a whole. Due to significant cost post-slaughter phenotypic measurement, genetic architecture tenderloin weight (TLNW) rib (RIBW)—important components pig value—remain unknown. In this study, we conducted genome-wide association studies (GWAS) TLNW RIBW traits in population 431 Duroc × Landrace Yorkshire (DLY) pigs....
Farm animals raised under free-range (FR) systems are assumed to have improved welfare and higher-quality products that better eat than intensively reared animals. However, the modulations limited in scientific investigations. In this study, we compared 2 rearing (FR cage) their effects on chickens, including production performance, product quality, body condition, physiological indicators, gene expression. By using a match-mismatch design which each treatment was transferred other during...
The German Longhaired Pointer (GLP) breed is a versatile pointer dog breed. In the current study, we investigated genetic diversity of these dogs based on SNP array data and compared it to 11 other setter breeds. results show that GLPs have relatively low level inbreeding among addition, with availability pedigree information GLPs, demonstrate correlation between pedigree-based genotype-based coefficients was high (R = 0.89 0.85). By investigating population structure 12 breeds showed GLP...
Genetic variation in the regulation of gene expression contributes substantially to phenotypic variation. Understanding how DNA sequences and epigentic modifications leads remains a challenging task. In hybrid animals where cellular environments are homogeneous, differences between paternal maternal alleles must be due cis sequence or epigenic differences. Therefore, mapping is powerful approach efficiently identify characterize genes under through mechanisms cis. this study, using...
Abstract Historically, Chinese indigenous pigs were introduced to Europe centuries ago with the aim of enhancing economically important traits in European breeds. In recent decades, there has been a reciprocal introduction commercial breeds China for pig breeding. Our study investigated genomes 418 pigs, revealing genomics landscape bi-directional introgression patterns between and populations. We noted common occurrence incomplete linkage disequilibrium structural variations (SVs) adjacent...