Jian Zhang

ORCID: 0000-0003-3869-1866
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About
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Research Areas
  • Animal Virus Infections Studies
  • Virus-based gene therapy research
  • Viral gastroenteritis research and epidemiology
  • Animal Nutrition and Physiology
  • Animal Disease Management and Epidemiology
  • Animal Behavior and Welfare Studies
  • Insect and Pesticide Research
  • Respiratory viral infections research
  • Microbial infections and disease research
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Insect Utilization and Effects
  • CRISPR and Genetic Engineering
  • melanin and skin pigmentation
  • Immune Cell Function and Interaction
  • Environmental DNA in Biodiversity Studies
  • Genetic and phenotypic traits in livestock
  • Aquaculture Nutrition and Growth
  • Animal Genetics and Reproduction
  • Plant and animal studies
  • Constructed Wetlands for Wastewater Treatment
  • Livestock and Poultry Management
  • Effects of Environmental Stressors on Livestock
  • Plant Virus Research Studies

Shandong Normal University
2024

Shandong University
2024

Yantai University
2024

Key Laboratory of Guangdong Province
2022

Heilongjiang Bayi Agricultural University
2022

Beijing Academy of Agricultural and Forestry Sciences
2018-2022

University of Georgia
2020

South China Agricultural University
2019

Harbin Veterinary Research Institute
2015-2018

Chinese Academy of Agricultural Sciences
2015-2018

Porcine epidemic diarrhea virus (PEDV) is a worldwide-distributed alphacoronavirus, but the pathogenesis of PEDV infection not fully characterized. During infection, type I interferon (IFN) key mediator innate antiviral responses. Most coronaviruses develop some strategy for at least partially circumventing IFN response by limiting production and delaying activation response. However, molecular mechanisms which antagonizes effects have been Especially, how impacts signaling components has...

10.1128/jvi.01091-16 article EN Journal of Virology 2016-07-07

Poultry welfare has been extensively studied; however, there is a lack of rigorous scientific knowledge relating to the different aspects factors and how this may contribute production quantity product quality as well chickens. Therefore, we conducted an integrated study compare in chickens by providing free dietary choice under cage rearing, further comparing rearing with free-range rearing. One hundred each were allocated group conventional feeding (CC), mealworms (FDM), fresh grass...

10.3390/ani8060084 article EN cc-by Animals 2018-06-01

Effects of dietary metabolizable energy (ME) and crude protein (CP) level on performance, egg quality biochemical parameters were studied in a dual-purpose chicken-Beijing You Chicken (BYC) at peak laying period. A 3 × factorial experiment was arranged, including levels ME (11.31, 11.51, 11.71 MJ/kg) CP (14%, 15%, 16%). The results showed that alone the interaction by affected total feed intake (TFI) during 27-30 wks, mortality rate 27-34 wks age (p = 0.018), with highest found 11.31 MJ/kg...

10.1080/10495398.2022.2114001 article EN Animal Biotechnology 2022-08-26

Black coat color in pigs is determined by the dominant E allele at MC1R locus. Through comparing gene sequences between recessive e and ED1 alleles, we identified four missense mutations that could affect protein function for eumelanin synthesis. With aim of devising a genetic modification method pig manipulation, mutated Duroc breed to using CRISPR-mediated homologous recombination mutation substitutions The MC1R-modified generated replacement strategy displayed uniform black across body. A...

10.3390/ijms231810356 article EN International Journal of Molecular Sciences 2022-09-08

Farm animals raised under free-range (FR) systems are assumed to have improved welfare and higher-quality products that better eat than intensively reared animals. However, the modulations limited in scientific investigations. In this study, we compared 2 rearing (FR cage) their effects on chickens, including production performance, product quality, body condition, physiological indicators, gene expression. By using a match-mismatch design which each treatment was transferred other during...

10.1093/jas/sky314 article EN Journal of Animal Science 2018-08-28

Infectious bronchitis (IB) causes significant economic losses in the global poultry industry. Control of IB is hindered by genetic diversity causative agent, infectious virus (IBV), which has led to emergence several serotypes that lack complete serologic cross-protection. Although serotyping requires immunologic characterization, genotyping an efficient means identify IBVs detected samples. Sanger sequencing S1 subunit spike gene currently used genotype IBV; however, universal PCR was...

10.1177/1040638720910107 article EN Journal of Veterinary Diagnostic Investigation 2020-03-05

Heilongjiang province is the main cattle-producing area in China, and molecular epidemiological studies of bovine viral diarrhea viruses (BVDV) cattle have not been performed province.The objective this research was to determine genetic clinical characteristics BVDV cattle.Fifty-three BVDV-positive samples were collected from 22 farms Heilongjiang, 5´-untranslated region (5´-UTR) used carry out a phylogenetic analysis viruses.The similarity 5´-UTR sequences among these BVDVs 84.2%-100%,...

10.22099/ijvr.2021.38650.5625 article EN PubMed 2022-01-01

Soluble CD16 (sCD16) is closely correlated with chronic diseases in humans. Here, plasma sCD16 levels pigs were increased by infection porcine reproductive and respiratory syndrome virus (PRRSV) but not epidemic diarrhea virus, circovirus type 2 pseudorabies virus. Of interest, PRRSV attached to blood neutrophils reduced surface expression on neutrophils. In vitro data confirmed that caused shedding Further analyses revealed ADAM17 was involved shedding. Thus, our findings suggest increase...

10.1099/jgv.0.000368 article EN Journal of General Virology 2015-12-11
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