A5077413706- Forensic Entomology and Diptera Studies
- Insect and Pesticide Research
- Reproductive Physiology in Livestock
- Genetic and phenotypic traits in livestock
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Animal Genetics and Reproduction
- Reproductive System and Pregnancy
- Diptera species taxonomy and behavior
- T-cell and Retrovirus Studies
- Forest Insect Ecology and Management
- Virus-based gene therapy research
- Insect Utilization and Effects
- Insect behavior and control techniques
- Genetic Mapping and Diversity in Plants and Animals
- CRISPR and Genetic Engineering
- MicroRNA in disease regulation
- Leech Biology and Applications
- RNA modifications and cancer
- Identification and Quantification in Food
- Insect and Arachnid Ecology and Behavior
- Meat and Animal Product Quality
- Adipose Tissue and Metabolism
- Immune Response and Inflammation
- Animal Behavior and Welfare Studies
Guangdong Academy of Agricultural Sciences
2020-2025
Xinjiang Medical University
2024-2025
Central South University
2011-2024
Institute of Forensic Science
2024
Poultry Research Institute
2024
Reproductive & Genetic Hospital CITIC-Xiangya
2023
Ji Hua Laboratory
2022-2023
University of California, Los Angeles
2020
South China Agricultural University
2012-2018
The mechanisms by which organisms adapt to variable environments are a fundamental question in evolutionary biology and important protect species response changing climate. An interesting candidate study this is the honey bee Apis cerana, keystone pollinator with wide distribution throughout large variety of climates, that exhibits rapid dispersal. Here, we resequenced genome 180 A. cerana individuals from 18 populations China. Using population genomics approach, observed considerable...
In pig production, inefficient feed digestion causes excessive nutrients such as phosphorus and nitrogen to be released the environment. To address issue of environmental emissions, we established transgenic pigs harboring a single-copy quad-cistronic transgene simultaneously expressing three microbial enzymes, β-glucanase, xylanase, phytase in salivary glands. All enzymes were successfully expressed, non-starch polysaccharides (NSPs) phytate feedstuff was enhanced. Fecal outputs reduced by...
H. longicornis is used as an experimental animal model for the study of three-host ticks due to its special life cycle and easy maintenance in laboratory reproduction. The goes through a tightly regulated adapt changing host environment, these stages transition are also accompanied by proteome changes body. Here, we isobaric tags relative absolute quantification (iTRAQ) technique systematically describe analyze dynamic expression protein molecular basis seven differential developmental...
Background/Objectives: Fat deposition traits in pigs directly influence pork flavor, tenderness, and juiciness are closely linked to overall quality. The Tibetan pig, an indigenous breed China, not only possesses a high intramuscular fat content but also exhibits unique metabolism pattern due long-term adaptation harsh environments. This makes it excellent genetic physiological model for investigating characteristics. Adipose tissue from different body regions displays varying morphologies,...
The process of transgenesis involves the introduction a foreign gene, transgene, into genome an animal. Gene transfer by pronuclear microinjection (PNI) is predominant method used to produce transgenic animals. However, this technique does not always result in germline offspring and has low success rate for livestock. Alternate approaches, such as somatic cell nuclear using fibroblasts, do show increase efficiency compared PNI, while viral-based hampered issues regarding transgene size...
Gram-negative bacterial infections pose a significant threat to public health. Toll-like receptor 4 (TLR4) recognizes lipopolysaccharide (LPS) and induces innate immune responses, autophagy, cell death, which have major impacts on the body’s physiological homeostasis. However, role of TLR4 in LPS-induced autophagy apoptosis large mammals, are closer humans than rodents many characteristics, remains unknown. So far, few reports focus relationship between TLR, mammal levels, we urgently need...
Background Long non-coding RNAs (lncRNAs) have been reported to modulate cardiovascular diseases, and expression dynamics of lncRNAs in the bloodstream were proposed be potential biomarkers for clinical diagnosis. However, few diseases-related circulating identified their prediction power has not investigated depth. Here we report a new lncRNA, atherosclerotic plaque pathogenesis associated transcript ( APPAT ), evaluated its role predicting ability development. Methods was analyzed screened...
Medicinal leeches in the genus Hirudo have been utilized for therapeutic procedures thousands of years. To date, six known species are widely distributed different regions Eurasian continent. In this study, a new medicinal leech Hirudotianjinensis Liu, sp. nov. is described based upon specimens collected from Tianjin City, China. The can be distinguished its congeners by combination characters: blackish green dorsum with five continuous yellow longitudinal stripes; sensillae on dorsal...
Muscle fiber properties exert a significant influence on pork quality, with cross-sectional area (CSA) being crucial parameter closely associated various meat quality indicators, such as shear force. Effectively identifying and segmenting muscle fibers in robust manner constitutes vital initial step determining CSA. This is highly intricate time-consuming, necessitating an accurate automated analytical approach. One limitation of existing methods their tendency to perform well high...
Early pregnancy diagnosis in sows can significantly improve the efficiency of pig industry. Exosomes are membrane-covered nanovesicles that transport microRNAs (miRNAs) and other molecular signals between cells. In species, serum exosome-derived miRNAs serve as good biomarkers diseases different physiological states, including status. We hypothesized circulating might be used to differentiate status early several days after insemination pigs. To test this hypothesis, we randomly assigned...
Adipose tissue, an indispensable organ, fulfils the pivotal role of energy storage and metabolism is instrumental in maintaining dynamic equilibrium health organism. Adipocyte hypertrophy adipocyte hyperplasia (adipogenesis) are two primary mechanisms fat deposition. Mature adipocytes obtained by differentiating mesenchymal stem cells into preadipocytes redifferentiation. However, orchestrating adipogenesis remain unclear. Autophagy, alternative cell death pathway that sustains intracellular...
With the development of molecular identification, there has been a great deal discussion about feature mitochondrial DNA (mtDNA) fragments. Although longer fragments may minimize stochastic variation across taxa and be more likely to reflect broader patterns nucleotide divergence, shorter have many advantages, such as quick, easy economical. Extensive application long mtDNA segments for species identification cannot always achieved result constraints in time money. In present study, method...
The present study aimed to investigate the colonization process of epithelial bacteria attached rumen and intestinal tract tissue during development goats after birth. However, this from fetus adulthood was very limited. In goats, cecum are two important fermentation organs, it is acquisition neonatal microbiome, as well difference between these organs. To characterize microbial establishment dynamic changes in adulthood, we performed 16S rRNA gene sequencing for 106 samples 47 individuals...
Abstract Sarcophaga peregrina is considered to be of great ecological, medical and forensic significance, has unusual biological characteristics such as an ovoviviparous reproductive pattern adaptation feed on carrion. The availability a high‐quality genome will help further reveal the mechanisms underlying these charcateristics. Here we present de novo‐assembled at chromosome scale for S. . final assembled was 560.31 Mb with contig N50 3.84 Mb. Hi‐C scaffolding reliably anchored six...
Different types of skeletal myofibers exhibit distinct physiological and metabolic properties that are associated with meat quality traits in livestock. Alternative splicing (AS) pre-mRNA can generate multiple transcripts from an individual gene by differential selection splice sites. N6-methyladenosine (m6A) is the most abundant modification mRNAs, but its regulation for AS different muscles remains unknown. RESULTS: We characterized events m6A methylation pattern pig oxidative glycolytic...
Blow flies are among the most important insects in forensic entomology casework. Identification of blow fly species can be a time consuming and difficult task, especially at their early development stages. Present DNA-based technologies provide promising identification method for these forensically calliphorids. The cytochrome oxidase subunit I (COI) sequence has been applied as suitable DNA marker calliphorid many years; however, limitation exists using short to determine genetically close...
Prenatal mortality remains a significant concern to the pig farming industry around world. Spontaneous fetal loss ranging from 20 45% by term occur after fertilization, with most of happening during implantation period. Since factors regulating high rates early conceptus phases are poorly understood, we sought analyze overall gene expression changes this period, and identify molecular mechanisms involved in development. This work employed Illumina's next-generation sequencing (RNA-Seq)...