A5100730226- Genetic Mapping and Diversity in Plants and Animals
- Genetic and phenotypic traits in livestock
- Cancer-related molecular mechanisms research
- Genetics and Plant Breeding
- Plant nutrient uptake and metabolism
- Genetic diversity and population structure
- Photodynamic Therapy Research Studies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Biological and pharmacological studies of plants
- Animal Genetics and Reproduction
- Cancer and Skin Lesions
- Mass Spectrometry Techniques and Applications
- Viral Infections and Immunology Research
- Pharmacological Effects and Assays
- Genomic variations and chromosomal abnormalities
- Genetic and rare skin diseases.
- Microbial Metabolic Engineering and Bioproduction
- Plant and animal studies
- Forensic and Genetic Research
- Chromosomal and Genetic Variations
- Virus-based gene therapy research
- Yersinia bacterium, plague, ectoparasites research
- Insect and Arachnid Ecology and Behavior
- CRISPR and Genetic Engineering
- Analytical Chemistry and Sensors
Dalian University of Technology
2023
South China Agricultural University
2020-2022
Jiangxi Agricultural University
2016-2019
Anhui Agricultural University
2019
Huazhong University of Science and Technology
2017
Shandong Agricultural University
2010-2013
Buffalo State University
2001
University at Buffalo, State University of New York
2001
Abstract Bamaxiang pig is from Guangxi province in China, characterized by its small body size and two‐end black coat colour. It an important indigenous breed for local pork market excellent animal model biomedical research. In this study, we performed genomewide association studies (GWAS) on 43 growth carcass traits 315 purebred pigs based a 1.4 million SNP array. We observed considerable phenotypic variability the pigs. The corresponding heritability varied greatly across ranged 9.0% to...
Abstract Laiwu pigs are a Chinese indigenous breed that is renowned for its exceptionally high intramuscular fat content (average greater than 6%), providing an excellent genetic resource the improvement of meat quality modern commercial pigs. To uncover diversity, population structure, signature selection, and potential exotic introgression in this breed, we sampled 238 from state‐supported conservation genotyped these individuals using GeneSeek 80K SNP BeadChip. We then conducted in‐depth...
Heterozygosity can effectively reflect the diverse models of population structure and demographic history. However, genomic distribution heterozygotes correlation between regions heterozygosity (runs heterozygosity, ROHet) phenotypes are largely understudied in livestock. The objective this study was to identify ROHet Duroc pig genome, investigate relationships eight important economic traits. Here, we genotyped 3,770 American (S21) 2,096 Canadian (S22) pigs using 50 K single nucleotide...
Runs of homozygosity (ROH) are widely used to investigate genetic diversity, demographic history, and positive selection signatures livestock. Commercial breeds provide excellent materials reveal the landscape ROH shaped during intense process. Here, we GeneSeek Porcine 50K single-nucleotide polymorphism (SNP) Chip data 3,770 American Duroc (AD) 2,096 Canadian (CD) pigs analyze genome-wide ROH. First, showed that AD had a moderate differentiation with CD pigs, more abundant diversity...
Chinese indigenous pig breeds in the Taihu Lake (TL) region of Eastern China are well documented by their exceptional prolificacy. There seven this including Meishan (MS), Erhualian (EHL), Jiaxing Black (JXB), Fengjing (FJ), Shawutou (SWT), Mi (MI), and Hongdenglong (HDL). At present, these facing a great threat population decline, inbreeding depression lineage admixture since Western commercial pigs have dominated industry. To provide better conservation strategies identify candidate genes...
Jiangquhai pigs are one of the 42 representative local breeds listed in national livestock genetic resources conservation project China. This breed is known for its prolificacy, desirable meat quality, and excellent adaptability to crude feed environments. In this study, we genotyped 105 from state farm using GeneSeek GGP Porcine 80K SNP chip, explored data unravel diversity, evolutionary phylogeny, signatures selection, population structure a context 33 global breeds. Five indices observed...
Objectives: Previous studies of archaeology and history suggested that the rise prosperity Bronze Age culture in East Asia had made essential contribution to formation early state civilization this region. However, impacts perspective genetics remain ambiguous. genetic researches indicated Y-chromosome Q1a1a-M120 N1a2a-F1101 may be two most important paternal lineages among people ancient northwest China. Here, we investigated 9,000-years haplogroup with revised phylogenetic tree spatial...
Runs of homozygosity (ROH) are widely used to estimate genomic inbreeding, which is linked inbreeding depression on phenotypes. However, the adverse effects specific homozygous regions phenotypic characteristics rarely studied in livestock. In this study, 50 K SNP data 3,770 S21 Duroc (American origin) and 2,096 S22 (Canadian pigs were investigate harmful ROH five economic traits. The results showed that two lines had different numbers distributions unfavorable ROHs, may be related selection...
Chinese goats are an important group of worldwide. However, there few studies on the conservation priority, genetic relationship, and potential gene flow between global goat breeds. Here, we genotyped 239 from populations Guangfeng Ganxi breeds using GoatSNP50 BeadChip. The population structure, selection signatures introgression these were analyzed in context 36 First, showed that had largest effective sizes across 13 generations ago. Nevertheless, have recently experienced a high degree...
Abstract Pigs show extensive variation in exterior appearance. This has been explored as one of the selection targets to form breeding features pig industry. In this study, a customized Affymetrix Axiom Pig1.4M array plate was used conduct genome‐wide association studies ( GWAS ) for two traits—spotted coat color SC and facial type FT )—in Chinese Dongxiang spotted pigs. Two 12 single nucleotide polymorphisms SNP s) were identified be associated with at 5% significant level, respectively. Of...
Objective Copy number variations (CNVs) are a major source of genetic diversity complementary to single nucleotide polymorphism (SNP) in animals. The aim the study was perform comprehensive genomic analysis CNVs based on high density whole-genome SNP markers Chinese Dongxiang spotted pigs. Methods We used customized Affymetrix Axiom Pig1.4M array plates containing 1.4 million SNPs and PennCNV algorithm identify porcine autosomes Then, next generation sequence data confirm detected CNVs....
Imaging in biological systems has become one of the most relied upon tools study human disease. Two-photon excitation methodology laser scanning microscopy resulted 3D-imaging capability not easily achieved one- photon systems. Our Institute, conjunction with Andrew Schally (Noble Laureate, Tulane University), used two- (TPLSM) to understand real time cellular transport chemotherapeutic agent, Luteinizing Hormone-Releasing Hormone-Doxorubicin (AN152) covalently coupled a novel two-photon...