A5052199112- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Genetic and phenotypic traits in livestock
- Circular RNAs in diseases
- Genetic Mapping and Diversity in Plants and Animals
- Microbial infections and disease research
- Extracellular vesicles in disease
- Animal Genetics and Reproduction
- Nerve injury and regeneration
- RNA Interference and Gene Delivery
- Mycobacterium research and diagnosis
- Genetic Associations and Epidemiology
- Molecular Biology Techniques and Applications
- Reproductive System and Pregnancy
- Epigenetics and DNA Methylation
- Reproductive Biology and Fertility
- Retinal Development and Disorders
- Macrophage Migration Inhibitory Factor
- RNA modifications and cancer
- RNA Research and Splicing
- Bacteriophages and microbial interactions
- Retinal Diseases and Treatments
- Genomics and Phylogenetic Studies
- Neurogenesis and neuroplasticity mechanisms
- Reproductive Physiology in Livestock
Jinan University
2023-2025
General Hospital of Shenyang Military Region
2023-2025
Shandong University of Traditional Chinese Medicine
2025
Shihezi University
2018-2024
Wenzhou Medical University
2024
Tebian Electric Apparatus (China)
2023-2024
Xiangya Hospital Central South University
2021-2023
Central South University
2013-2023
Jiangxi Agricultural University
2015-2023
First Affiliated Hospital of Wannan Medical College
2023
Abstract Resequencing a number of individuals various breeds as reference population and imputing the whole-genome sequences that were genotyped with medium-density chips to perform an association study is very efficient strategy. Previously, we performed genome-wide (GWAS) lumbar using 60K SNPs from porcine Illumina in 418 Sutai pigs did not detect any significant signals. Therefore, imputed 403 deeply resequenced tests. We identified quantitative trait locus (QTL) for SSC1 P value 9.01E-18...
Abstract Bamaxiang pig is from Guangxi province in China, characterized by its small body size and two‐end black coat colour. It an important indigenous breed for local pork market excellent animal model biomedical research. In this study, we performed genomewide association studies (GWAS) on 43 growth carcass traits 315 purebred pigs based a 1.4 million SNP array. We observed considerable phenotypic variability the pigs. The corresponding heritability varied greatly across ranged 9.0% to...
Abstract Epigenetic regulation of neuronal transcriptomic landscape is emerging to be a key coordinator mammalian neural regeneration. The roles two histone 3 lysine 27 (H3K27) demethylases, Kdm6a/b, in controlling neuroprotection and axon regeneration are investigated here. Deleting either Kdm6a or Kdm6b leads enhanced sensory the peripheral nervous system (PNS), whereas central (CNS), only deleting retinal ganglion cells (RGCs) significantly enhances optic nerve Moreover, both function...
Against the background of globalization, circulation range traditional Chinese medicinal materials is constantly expanding, and phenomena mixed origins counterfeiting are becoming increasingly serious. Tracing origin great significance for ensuring their quality, safety, effectiveness. Laser-induced breakdown spectroscopy (LIBS), as a rapid non-destructive element analysis technique, can be used tracing materials. Deep learning not only handle non-linear relationships but also automatically...
Strawberry (Fragaria x ananassa) is an allopolyploid species with diverse and complex transcripts. The regulatory mechanisms of fruit development maturation have been extensively studied; however, little known about the signaling that direct this process in octoploid strawberry ananassa). Here, we used long-read sequencing (LRS) technology RNA-seq analysis to investigate diversity complexity polyploid transcriptome differentially expressed transcripts along four successive developmental...
The dynamic process involving the selection and maturation of follicles is regulated controlled by a highly synchronized exquisitely timed cascade gene expression. Studies have shown that long non-coding RNA (lncRNA) essential for normal maintenance animal reproductive function has an important regulatory in ovarian development hormone secretion. In this study, total 2076 lncRNAs (1362 known 714 new lncRNAs) 25,491 mRNAs were identified libraries constructed from Duroc ovaries on days 0, 2 4...
Summary Under natural farming, environmental pathogenic microorganisms may invade and affect swine lungs, further resulting in lung lesions. However, few studies on microbiota their potential relationship with lesions were reported. Here, we sampled 20 pigs from a hybrid herd raised under conditions; recorded lung‐lesion phenotype investigated microbial communities by sequencing the V3‐V4 region of 16S rRNA gene for each individual. We found reduced diversity but more biomass severe‐lesion...
Abstract Accumulating evidence suggests that circular RNAs (circRNAs) are abundant and play critical roles in the nervous system. However, their functions axon regeneration after neuronal injury unclear. Due to its robust capacity, peripheral system is ideal for seeking regulatory circRNAs regeneration. In present work, we obtained an expression profile of dorsal root ganglions (DRGs) rat sciatic nerve crush by RNA sequencing (RNA-Seq) found level circ-Spidr was obviously increased using...
Schwann cells (SCs) play an essential role in nerve injury repair. A striking feature of the cellular response to peripheral is proliferation SCs. Circular (circ)RNAs are enriched nervous system and involved physiologic pathologic processes. However, potential circRNAs SC post remains largely unknown. Using a sciatic crush model, we obtained expression profiling injured nerves rats by RNA sequencing bioinformatics analysis, further identified circRNA [circ–ankyrin repeat in‐between Ring...
The whole-genome sequences of progenies with low-density single-nucleotide polymorphism (SNP) genotypes can be imputed high accuracy based on the deep-coverage key ancestors. With this imputation technology, a more powerful genome-wide association study (GWAS) carried out using variants and phenotypes interest to overcome shortcomings low-power detection large confidence interval derived from SNP markers in classic studies. In study, 19 ancestors large-scale swine F2 White Duroc × Erhualian...
Prevalence of swine respiratory disease causes poor growth performance in and serious economic losses to the industry. In this study, a categorical trait enzootic pneumonia-like (EPL) score representing infection gradient disease, more likely pneumonia, was recorded herd 332 Chinese Erhualian pigs. According their EPL scores effect on weight gains, these pigs were grouped into controls (EPL ≤ 1) cases > 1). The gain case group reduced significantly at days 180, 210, 240 300 as compared...
Intravascular large B-cell lymphoma (IVLBCL) is a rare and highly malignant non-Hodgkin with uncommon clinical presentation poor prognosis. The diagnostic pitfall of IVLBCL mainly due to the fact that subtle histological changes could be easily overlooked, in addition its occurrence, non-specific variable presentations, absence significant mass lesions. purpose this study further explore clinicopathologic molecular features ensure an accurate diagnosis entity. Here, we retrospectively...