The purpose of this study was to identify loci associated with Mycobacterium avium subspecies paratuberculosis (Map) infection status in US Holsteins using the Illumina BovineSNP50 BeadChip whole genome single nucleotide polymorphism (SNP) assay. Two hundred forty-five cows from dairies New York, Pennsylvania and Vermont enrolled longitudinal herd studies between January 1999 November 2007 were assessed for presence Map both faecal tissue samples. An animal considered infected if any sample...

Genetic improvement in livestock populations can be achieved without significantly affecting genetic diversity if mating systems and selection decisions take relationships among individuals into consideration. The objective of this study was to examine the two commercial breeds pigs. Genotypes from 1168 Landrace (LA) 1094 Large White (LW) animals a breeding program Brazil were obtained using Illumina PorcineSNP60 Beadchip. Inbreeding estimates based on pedigree (F x) genomic information runs...

White striping (WS) is one of the most common myopathies identified in broiler chickens leading to substantial production losses, where incidence reaches 12% commercial chickens. It occurs primarily heavier being a modification breast muscle characterized by presence pale parallel streaks same orientation fibers. Since WS etiology remains unclear, we aimed identify biological and genetic mechanisms involved its occurrence through whole transcriptome analysis affected unaffected chicken...

Johne's disease, caused by Mycobacterium avium subspecies paratuberculosis (Map), is a fatal disease in cattle. The objective of this study was to identify loci associated with tolerance cows infected Map. Tolerance defined as cow's fitness at given level Map infection intensity. Fitness measured faecal cultures, and intensity culturing four gut tissues. quantitative phenotype numerical indexes cultures peak (peak tolerance, PT) average (average AT) tissue from 245 Holstein cows. categorical...

The objective of this research was to examine the population structure full-blood (100%) Wagyu cattle registered in United States with American Association, aim estimating and comparing levels inbreeding from both pedigree genotypic data. A total 4132 pedigrees were assessed used compute coefficients (FIT FST ) effective size (Ne data for period 1994 2011. In addition analysis, 47 representing eight prominent sire lines genotyped using Illumina BovineSNP50 BeadChip. Genotypic then estimate...

Performance traits are economically important and targets for selection in breeding programs, especially the poultry industry. To identify regions on chicken genome associated with performance traits, different genomic approaches have been applied last years. The aim of this study was application CornellGBS approach (134,528 SNPs generated from a PstI restriction enzyme) Genome-Wide Association Studies (GWAS) an outbred F2 population. We validated 91.7% these 134,528 after imputation missed...

Abstract Improvements on growth and carcass traits in the poultry industry have been achieved by intense selection for heavier chickens at early ages. This faster has caused serious problems due to insufficient skeletal structure development needed support musculature of modern broilers. The osteoprotegerin gene ( OPG ), located GGA2, is an important regulator bone metabolism reabsorption, being suggestive as a possible functional candidate associated with integrity chickens. study reports...

Cattle population history, breeding systems, and geographic subdivision may be reflected in runs of homozygosity (ROH), effective size ( N e ), linkage disequilibrium (LD) patterns. Thus, the assessment this information has become essential to implementation genomic selection on purebred crossbred cattle programs. In way, we assessed genotype 19 breeds raised Brazil belonging taurine, indicine, synthetic crossbreds, Iberian-derived locally adapted ancestries evaluate overall LD decay...

The cryopreservation of jaguar semen must be improved to produce high-quality biobanking doses. Until now, the rare studies freezing in species have only evaluated glycerol, always with a significant reduction sperm quality thawed semen. purpose this study was assess efficacy three cryoprotectants, dimethylsulfoxide (DMSO), glycerol (GLY), and methanol (MET), an LDL-based extender, as well effect thawing temperature on dosage quality. Five mature males history reproduction were used. On...

The objective of this study was to identify loci linked with bovine respiratory disease (BRD) and subsequently determine if these same were associated viral diarrhea virus persistent infection (BVD-PI) in affected calves or their dams. A genome-wide linkage using 312 microsatellites conducted BRD a Brahman × Hereford sire half-sib family. Disease incidence recorded from birth slaughter by daily monitoring. Linkage suggestive for QTL on BTA2 (F = 7.31, P 0.007) BTA26 10.46, 0.001). Six 7...

Interleukin-10 (IL-10) is a cytokine that plays an important role in the regulation of immune system. Gene polymorphisms IL-10 have been associated with different expression levels this cytokine. In hepatitis C virus infection, appears to interfere progression disease, viral persistence and response therapy. This study investigated genetic variability gene promoter between patients infected (HCV) healthy individuals, associating frequency aspects infection. case-control 260 who were HCV...

Genetic selection for production traits has resulted in a rapid improvement animal performance and development.Previous studies have mapped quantitative trait loci body weight at 35 41 days, drum thigh yield, onto chicken chromosome 4.We investigated this region single nucleotide polymorphisms their associations with important economic traits.Three positional candidate genes were studied: KLF3 (Krüeppel-like factor 3), SLIT2 (Slit homolog 2), PPARGC1A (peroxisome proliferator-activated...

Single nucleotide polymorphism (SNP) markers are used to study population structure and conservation genetics, which permits assessing similarities regarding the linkage disequilibrium information about relationship among individuals. To investigate genomic of 300 females 25 males from a commercial maternal pig line we analyzed extent, inbreeding coefficients using conventional pedigree data, stratification. The average (r2) was 0.291 ± 0.312 for all adjacent SNPs, distancing less than 100...

The intensification of the use artificial insemination in swine industry has increased interest to develop proper conditions store semen better for longer periods time without affecting its fertility. Trolox is a vitamin E analog with antioxidant property prevent oxidative stress. Therefore, objective this study was evaluate capacity on boar during storage period (86 h) at 15°C. For that, samples from 5 different boars were collected and diluted Long-Term (LT) extender addition concentration...

The United Kingdom and European Union have banned crates for pregnant sows. However, animals are kept in a restrictive environment up to four weeks after mating, leading stress different responses of the animals' immune system. Here, we used vaginal flushing gilts investigate whether housing systems or an experimental inflammatory challenge with lipopolysaccharide (LPS) can modify gilt microbiome. Alpha-diversity indices showed differences microbiota housed under (q = 0.04). Shannon...

Introduction: Cryptorchidism is a hereditary anomaly characterized by the incomplete descent of one or both testicles to scrotum. One challenges this that retained testicle maintains its endocrine function. As consequence, cryptorchid animals produce hormone-tainted meat in comparison castrated and are likely be more aggressive. can lead reduced animal welfare outcomes cause economic losses. Identifying genetic markers for cryptorchidism an essential step toward mitigating these negative may...

The giant anteater (Myrmecophaga tridactyla) is a member of the Myrmecophagidae family and now classified as "Vulnerable" due to risk extinction. In spite this, research on reproductive biotechnologies in species rare, semen collection has only been performed using electroejaculation date. Pharmaceutical through urethral catheterization become distinct method that being applied numerous wild animals. addition establishing species-specific setup, we compared acquired by three animals obtained...

Epigenetic mechanisms are important modulators of neurodevelopmental outcomes in the offspring animals challenged during pregnancy. Pregnant sows living a confined environment with stress and lack stimulation which may result expression stereotypies (repetitive behaviours without an apparent function). Little attention has been devoted to postnatal effects maternal offspring. We investigated how pregnant affected neuro-epigenome their piglets. focused on amygdala, frontal cortex,...