A5081982320- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Animal Genetics and Reproduction
- Cancer-related molecular mechanisms research
- Meat and Animal Product Quality
- Animal Nutrition and Physiology
- Reproductive Physiology in Livestock
- Genetics and Plant Breeding
- Adipose Tissue and Metabolism
- Animal Behavior and Welfare Studies
- Mesenchymal stem cell research
- Molecular Biology Techniques and Applications
- Effects of Environmental Stressors on Livestock
- Vector-Borne Animal Diseases
- Gene expression and cancer classification
- Muscle Physiology and Disorders
- Milk Quality and Mastitis in Dairy Cows
- MicroRNA in disease regulation
- Animal Disease Management and Epidemiology
- Vector-borne infectious diseases
- Postharvest Quality and Shelf Life Management
- Protein Hydrolysis and Bioactive Peptides
- Fish Ecology and Management Studies
- Livestock and Poultry Management
- Biotechnology and Related Fields
Universidade Federal dos Vales do Jequitinhonha e Mucuri
2018-2024
Universidade Federal de Viçosa
2010-2021
Brazilian Agricultural Research Corporation
2017
Reproductive traits such as number of stillborn piglets (SB) and teats (NT) have been evaluated in many genome-wide association studies (GWAS). Most these GWAS were performed under the assumption that normally distributed. However, both SB NT are discrete (e.g. count) variables. Therefore, it is necessary to test for better fit other appropriate statistical models based on distributions. In addition, although performed, biological meaning identified candidate genes, well their functional...
Seventy-two pigs of three genetic groups (Brazilian indigenous breed Piau, Commercial line and Crossbred) both sexes were slaughtered at four live weights (30, 60, 90 120 kg). Intramuscular fat (IMF) content in Longissimus dorsi muscle each animal was extracted correlated with candidate gene mRNA expression (ATN1, EEF1A2, FABP3, LDLR, MGP, OBSCN, PDHB, TRDN RYR1). Within slaughter weight kg, Piau Crossbred showed higher IMF (p < 0.05) than commercial animals, 2.48, 2.08 1.00% respectively....
We performed a genome-wide mapping for the age at first calving (AFC) with goal of annotating candidate genes that regulate fertility in Nellore cattle. Phenotypic data from 762 cows and 777k SNP genotypes 2,992 bulls were used. Single nucleotide polymorphism (SNP) effects based on single-step GBLUP methodology blocked into adjacent windows 1 Megabase (Mb) to explain genetic variance. explaining more than 0.40% AFC variance identified chromosomes 2, 8, 9, 14, 16 17. From these windows, we...
One of the most commonly used quality measurements pork is pH measured 24 h after slaughter. The probable mode inheritance for this trait oligogenic with several known major genes, such as PRKAG3. In study, we whole-genome SNP genotypes over 700 AI boars; a check, 42,385 SNPs remained association analysis. All boars were purebred Finnish Yorkshire. To account relatedness animals, pedigree-based relationship matrix was in mixed linear model to test effect on from loin. A bioinformatics...
Fertility traits are economically important in cattle breeding programs. Scrotal circumference (SC) measures repeatable, easily obtained, highly heritable, and positively correlated with female fertility sperm quality males. A useful approach to summarize SC over time is using nonlinear models, which specific of a few parameters biological interpretation. This facilitates the selection bulls larger maturity index (K), that is, early maturing animals. Because sex-limited trait, identifying...
Feed efficiency is one of the most important parameters that affect beef production costs. The energy metabolism skeletal muscle greatly contributes to variations in feed efficiency. However, information regarding differences proteins involved cattle divergently identified for scarce. In this study, we aimed investigate Nellore cattle, low and high residual intake using a proteomics approach. We further assessed expression candidate microRNAs as possible mechanisms controlling biosynthesis...
Cattle population history, breeding systems, and geographic subdivision may be reflected in runs of homozygosity (ROH), effective size ( N e ), linkage disequilibrium (LD) patterns. Thus, the assessment this information has become essential to implementation genomic selection on purebred crossbred cattle programs. In way, we assessed genotype 19 breeds raised Brazil belonging taurine, indicine, synthetic crossbreds, Iberian-derived locally adapted ancestries evaluate overall LD decay...
Integration of genomic data with gene network analysis can be a relevant strategy for unraveling genetic mechanisms. It used to explore shared biological processes between genes, as well highlighting transcription factors (TFs) related phenotypes interest. Unlike other species, gene–TF analyses have not yet been applied horse traits. We aimed (1) identify candidate genes associated performance via systematic review, and (2) build networks from the identified aiming highlight most...
Number of teats (NT) is an important trait affecting both piglet's welfare and the production level pig farms. Biologically, embryonic mammary gland development requires coordination many signaling pathways necessary for proper teats. Several QTL NT have been identified; however, further analysis still lacking. Therefore, gene networks derived from genomewide association study (GWAS) results can be used to examine shared functions putative candidate genes. Besides, such analyses may also...
The beef cattle industry has experienced a shift driven by market demand for healthier meat, cost efficiency and environmental sustainability in recent years. Consequently, there been growing focus on the fatty acids content functions of meat breeding programmes. Besides, deeper understanding biological mechanisms influencing expression different phenotypes related to acid profiles is crucial. In this study, we aimed identify Single-Nucleotide Variants (SNV) Insertion/Deletion (InDels) DNA...
A large number of quantitative trait loci (QTL) for meat quality and carcass traits has been reported in pigs over the past 20 years. However, few QTL have validated biological meaning genes associated to these underexploited. In this context, a meta-analysis was performed compare significant markers with meta-QTL previously literature. Genome association studies were 12 traits, from which 144 SNPs found out be (P < 0.05). They used build Association Weight Matrix, matrix framework...
The aim of the present study was to propose and evaluate use factor analysis (FA) in obtaining latent variables (factors) that represent a set pig traits simultaneously, for genome-wide selection (GWS) studies. We used crosses between outbred F2 populations Brazilian Piau X commercial pigs. Data were obtained on 345 pigs, genotyped 237 SNPs, with 41 traits. FA allowed us obtain four biologically interpretable factors: "weight", "fat", "loin", "performance". These factors as dependent...
Summary Pig is an important animal for meat production; this generally associated with characteristics determined prenatally during myogenesis. Expressed sequence tags ( EST ) can provide direct information on the transcriptome and indirect relation between genome phenotype, giving about differentially expressed genes DEG ). In work, identification annotation of from libraries three pig breeds D uroc, L arge W hite ocal B reed P iau) were performed followed by real‐time PCR analyses pre‐...
MicroRNAs are a class of naturally occurring non-coding RNAs. Typically they ∼22 nucleotides long and suppress translation their targets genes. Several laboratories have attempted to identify miRNAs from pig muscle the bioinformatics strategies using ESTs proved be successful for this aim. In study we report an in silico identification ncRNA EST libraries focusing on novel further investigated differential expression pigs (known novel) by quantitative real-time PCR during pre- postnatal...