A5088154020- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Animal Nutrition and Physiology
- Animal Behavior and Welfare Studies
- Meat and Animal Product Quality
- Effects of Environmental Stressors on Livestock
- Genetics and Plant Breeding
- Wheat and Barley Genetics and Pathology
- Genomics and Chromatin Dynamics
- Agriculture and Biological Studies
- Sperm and Testicular Function
- Genetic diversity and population structure
- Vector-Borne Animal Diseases
- Reproductive Physiology in Livestock
- Testicular diseases and treatments
- Helminth infection and control
- Livestock Farming and Management
- Animal Genetics and Reproduction
- Animal Virus Infections Studies
Topigs Norsvin (Netherlands)
2015-2025
Wageningen University & Research
2016-2019
Genomic prediction of purebred animals for crossbred performance can be based on a model that estimates effects single nucleotide polymorphisms (SNPs) in purebreds performance. For performance, SNP might breed-specific due to differences between breeds allele frequencies and linkage disequilibrium patterns SNPs quantitative trait loci. Accurately tracing the breed-of-origin alleles (BOA) three-way crosses is possible with recently developed procedure called BOA. A accounts (BOA model), has...
For some species, animal production systems are based on the use of crossbreeding to take advantage increased performance crossbred compared purebred animals. Effects single nucleotide polymorphisms (SNPs) may differ between and animals for several reasons: (1) differences in linkage disequilibrium SNP alleles a quantitative trait locus; (2) genetic backgrounds (e.g., dominance epistatic interactions); (3) environmental conditions, which result genotype-by-environment interactions. Thus,...
Abstract Background The objectives of this study were to estimate genetic parameters and studying the influence early-life parental factors on semen traits boars. dataset included measurements 449,966 ejaculates evaluated using a Computer-Assisted Sperm Analysis (CASA) system from 5692 artificial insemination (AI) In total, we considered 16 measured fresh 6 sperm motility after storage. Early-life effects dam’s parity, ages dam sire, gestation length, litter size, sex ratio, number piglets...
Although breeding programs for pigs and poultry aim at improving crossbred performance, they mainly use training populations that consist of purebred animals. For some traits, e.g. residual feed intake, the genetic correlation between performance is low thus including animals in population required. With animals, effects single nucleotide polymorphisms (SNPs) may be breed-specific because linkage disequilibrium patterns a SNP quantitative trait locus (QTL), allele frequencies substitution...
Selection for feed efficiency (FE) is a strategy to reduce the production costs per unit of animal product, which one major objectives current breeding programs. In pig breeding, selection FE and other traits traditionally takes place based on purebred (PB) performance at nucleus level, while pork typically makes use crossbred animals (CB). The success this selection, therefore, depends genetic correlation between PB CB (rpc) (rg) that are currently under selection. Different being used...
Seasonal infertility is often observed as anestrus and a lower conception rate resulting in reduced farrowing (FR) during late summer early autumn. This regarded an effect of heat stress; however, we reduction the FR sows even after correcting for ambient temperature our data. Therefore, added change photoperiod analysis considering its on sow fertility. Change was modeled using cosine day first insemination within year. On average, decreased by 2% autumn with decreasing daily compared...
Cryptorchidism and scrotal/inguinal hernia are the most frequent congenital defects in pigs. Identification of genomic regions that control these is great interest to breeding programs, both from an animal welfare point view as well for economic reasons. The aim this genome-wide association study (GWAS) was identify single nucleotide polymorphisms (SNPs) strongly associated with defects. Genotypes were available 2570 Large White (LW) 2272 Landrace (LR) Breeding values estimated based on 1...
A major objective of pork producers is to reduce production cost. Feeding may account for over 75% costs. Thus, selecting pigs feed efficiency (FE) traits a priority in pig breeding programs. While the Americas, are typically fed high-input diets, based on corn and soybean meal (CS); Western Europe, commonly diets wheat barley with high amounts added protein-rich coproducts (WB), e.g., from milling seed-oil industries. These two feeding scenarios provided realistic setting investigating...
Pig-breeding businesses have resulted in global breeding programs that select pigs to perform well on high-energy high-protein diets, which are traditionally based corn and soybean meal. Nowadays, there is a shift toward diets cereals co-products, therefore, high dietary inclusion of co-products can modify the expected performance these pigs. The objective this study was evaluate effect feeding cereals–alternative ingredients diet (CA-diet) compared corn–soybean meal (CS-diet) growth...
The genome in crossbred animals is a mosaic of genomic regions inherited from the different parental breeds. We previously showed that effects haplotypes strongly associated with performance are depending upon which breed they inherited, however, majority not or only weakly performance. Therefore, our objective was to develop model distinguishes between selected single nucleotide polymorphisms (SNP) and all remaining SNP. For SNP, breed-specific allele were fitted whereas for SNP it assumed...
This study investigated if the allele effect of a given single nucleotide polymorphism (SNP) for crossbred performance in pigs estimated genomic prediction model differs depending on its breed-of-origin, and how these are related to effects purebred performance. SNP-allele substitution were commonly used SNP panel using best linear unbiased with breed-specific partial relationship matrices. Estimated breeding values converted by breed-of-origin. Differences between crossbred,...
In pig production, the production animals are generally three- or four-way crossbreeds. Reliable information regarding breed of origin slaughtered pigs is useful, even a prerequisite, for number purposes, e.g., evaluating potential effects on carcass grading. Genetic data from can easily be extracted and used crossbreed classification. current study, four classification methods, namely, random forest (RF), ADMIXTURE, partial least squares regression (PLSR), together with quadratic...
In pig breeding, selection commonly takes place in purebred (PB) pigs raised mainly temperate climates (TEMP) under optimal environmental conditions nucleus farms. However, pork production typically makes use of crossbred (CB) animals nonstandardized commercial farms, which are located not only TEMP regions but also tropical and subtropical (TROP). Besides the differences genetic background PB CB, climate conditions, between farms can lower correlation performance (PBTEMP) CB TROP (CBTROP)....
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Most deleterious variants are recessive and segregate at relatively low frequency. Therefore, high sample sizes required to identify these variants. In this study we report a large-scale sequence based genome-wide association (GWAS) in pigs, with total of 120,000 Large White 80,000 Synthetic breed animals imputed using reference population approximately 1,100 whole genome sequenced pigs. We over 20 million accuracies (R 2 >0.9) even for frequency (1–5% minor allele frequency). This...
The majority of the commercial slaughter pigs are crossbred animals. However, breeding efforts have been mainly focused on increasing genetic progress purebred populations. aim this work is to evaluate different strategies improve genomic prediction performance taking into account breed origin alleles in populations (breed-specific effects). Previous showed that marker effects estimated one cannot predict another (across-breed prediction). This might be due breed-specific caused by...
Several QTL regions affecting number of teats have been detected in commercial pig lines. In this study we follow the indirect effects index selection on different for two maternal lines 40K animals with imputed 555K SNP. total, 3 overlap between populations. For a Sus scrofa chromosome 7 (SSC7), underlying functional variation thoracic vertebrae located vertnin gene has also genotyped showing an allelic substitution effect nearly 0.4 both However, allele frequencies show opposite trend at...