- Anesthesia and Pain Management
- COVID-19 Clinical Research Studies
- MicroRNA in disease regulation
- Nausea and vomiting management
- Airway Management and Intubation Techniques
- Reproductive Biology and Fertility
- Renal Transplantation Outcomes and Treatments
- Cancer-related molecular mechanisms research
- Organ Transplantation Techniques and Outcomes
- COVID-19 Impact on Reproduction
- Tracheal and airway disorders
- Anesthesia and Sedative Agents
- Circular RNAs in diseases
- Corneal Surgery and Treatments
- Gynecological conditions and treatments
- Liver Disease and Transplantation
- Glaucoma and retinal disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Emotional Intelligence and Performance
- Pediatric Pain Management Techniques
- Neonatal Respiratory Health Research
- Autism Spectrum Disorder Research
- Anesthesia and Neurotoxicity Research
- Spine and Intervertebral Disc Pathology
- Children's Physical and Motor Development
Kalawati Saran Children's Hospital
2021-2024
All India Institute of Medical Sciences Bhopal
2021-2024
Delhi Technological University
2022-2024
Lady Hardinge Medical College
2021-2024
BLK Super Speciality Hospital
2024
Chirayu Medical College & Hospital
2024
Netaji Subhash Chandra Bose Medical College
2024
Sri Ramachandra Institute of Higher Education and Research
2024
Patna Medical College and Hospital
2024
Washington Hospital
2024
Background: Pregnancy-induced hypertension (PIH), a pregnancy-specific hypertensive disorder, is significant cause of maternal and perinatal morbidity mortality. Insufficient self-management knowledge among women with PIH may compromise effective blood pressure control. This study aimed to evaluate the attitudes regarding diagnosed PIH. Methods: A descriptive cross-sectional was conducted at Gynecology Outpatient Department tertiary care hospital in Lucknow, India. purposive sample 150...
Background: Circulating miRNAs (miRs) in the biofluids such as serum and plasma act potential biomarkers for early diagnosis, treatment prognosis. In present study, an attempt made to see expression of miR-21 20 cases Oral sub-mucous fibrosis (OSMF), squamous cell carcinoma 40 healthy volunteers. The was evaluated relation different demographical clinicopathological features sex, tobacco, pan-masala, alcohol, smoking clinical staging respectively with aim identify correlation oral pre-cancer...
Herpes zoster is a localised disease caused by reactivation of the varicella virus that enters cutaneous nerve endings during an earlier episode chicken pox, travels to dorsal root ganglia, and remains in latent form. The condition characterised occurrence multiple, painful, unilateral vesicles ulceration, shows typical single dermatome innervated or cranial sensory ganglion. Involvement three more dermatomes known as disseminated seen immunocompromised individuals. Complications herpes...
Abstract Leukemogenesis is a complex process that involves multiple stages of mutation in either hematopoietic stem or progenitor cells, leading to cancer development over time. Acute myeloid leukemia (AML) an aggressive malignancy affects cells. The major disease burden caused by immature blast which are eliminated using conventional chemotherapies. Unfortunately, relapse cause death AML patients, with 30%-80% experiencing it within 2 years initial treatment. dominant the presence...
Purpose There is limited data from the Indian subcontinent regarding surgical outcomes of coronavirus disease (COVID-19) patients. In this observational study, we aimed to evaluate postoperative after emergency surgery in COVID-19 patients compared concurrent age and gender-matched controls. We also sought analyze possible predictors mortality Methods This matched cohort study was conducted a tertiary care teaching hospital central India, between 1st July 2021 30th June 2022....
Direct laryngoscopy and tracheal intubation lead to increase in heart rate blood pressure. This can cause serious complications patients with coronary artery disease, reactive airways, or intracranial neuropathology. Preoperative anxiety is associated greater level of postoperative pain. Attenuation hemodynamic response are cornerstone better anesthetic outcome. Gabapentinoids (gabapentin pregabalin) have been known possess anxiolytic, analgesic, anticonvulsant properties.The aim this study...
Solid organ transplant (SOT) recipients are a complex, immunocompromised population in whom greater coronavirus disease 2019 (COVID-19) mortality has been reported compared with the general population. We examined retrospective cohort of 58 SOT first-wave COVID-19, comparing patients severe and nonsevere illness. Additionally, COVID-19. Organs transplanted included 38 kidneys, 8 livers, 5 hearts, 3 pancreases. Average recipient age was 57.4 years; 62% were male; 46.6% African American 36.2%...
Background and Aims: Our aim was to assess the efficacy of analgesia using ilioinguinal–iliohypogastric (IIIH) nerve block, transversus abdominis plane (TAP) block diclofenac after caesarean delivery (CD) under spinal anaesthesia (SA).] Methods: A total 457 healthy parturients undergoing CD SA were included in this prospective, observational study. Groups differed postoperative analgesic strategies received by parturient at end surgery: group D ( n = 148) intramuscular sodium, I 153)...
The time paediatric patients should resume oral intake after surgery is still ill-defined. No specific evidence suggests that the usual practice of postoperative fasting 4-6 h to reduce nausea and vomiting (PONV) beneficial. primary objective this study was assess occurrence PONV with early feeding compared conventional in children undergoing daycare under general anaesthesia.
We present a case of 28-year-old male who presented with acute abdomen and was later diagnosed to be having ruptured intra-abdominal seminoma hemoperitoneum, where the pre-operative diagnosis not made. Laprotomy complete excision were carried out. Rupture testicular is rare cause hemoperitoneum. The often difficult because history cryptorchidism provided imaging findings may non-specific. In patient without previous orchidectomy, aetiology should kept as differential diagnosis.
Objectives: To evaluate the effect of OSMF on eustachian tube function and to correlate it with various grades disease.Study Design: Twenty patients (40 ears) 20 healthy controls were evaluated for by test, tympanometry audiometry.Results: The audiometric tympanometric analysis showed no significant differences in hearing abilities between OSMF, indicating impairment.However, test revealed a statistically difference controls.Further, there was increase severity dysfunction...
Despite the progress made in development of new antiepileptic drugs (AEDs), poor response to them is a rising concern epilepsy treatment. Of several hypotheses explaining AED treatment failure, most promising theory overexpression multidrug transporters belonging ATP-binding cassette (ABC) transporter family at blood–brain barrier. Previous data show that AEDs themselves can induce these transporters, turn affecting their own brain bioavailability. Presently, this induction and underlying...
Squamous cell carcinoma of oral cavity is one the most common cancers Indian subcontinent with 5-year survival rate 50% despite recent advances in treatment. The aim present study was to cancer stem markers CD133 and Oct-4 squamous (OSCC) patients their correlation clinicopathological variables.
Background: Spinal anaesthesia in elderly patients is frequently associated with significant technical difficulties. can be given by either paramedian or median approach. Paramedian approach has been used as an alternative case of failure The goal this study to determine which these two approaches should preferred a first choice spinal patients.Methods: included 100 sex, aged 50 years and above, who received the midline (group M, n=50) PM, n=50).Results: success rate group was 100% compared...
: Studies have shown that apart from hereditary breast carcinomas, cancer susceptibility gene 1 (BRCA1) mutations conferring to its loss are seen in sporadic carcinomas (SBC) as well. The aim of the present study was assess BRCA1 methylation females presenting at King George's Medical University, Lucknow, with SBC by both immunohistochemistry (IHC) and PCR respect hormonal profile various morphological prognostic parameters. primary objective look for association between protein expression...
Introduction: Patients with cancer suffer from a wasting syndrome associated anorexia/cachexia. Anorexia is marked loss of appetite and/or an aversion to food. Cachexia body mass and often weakness, fatigue leading poor quality life. It has been observed in those individuals oral submucous fibrosis (OSMF), premalignant condition, are generally thin there seems be relation between consumption areca nut these individuals. Aims: Evaluation cachexia OSMF patients based on the criteria given for...
Various anatomical and physiological factors make intubation in infants challenging. C-MAC videolaryngoscope shows better results as compared to the conventional direct laryngoscopy for infants. McGrath MAC size-1 with a disposable Macintosh type blade has recently been introduced use not formally evaluated this population.This study aims evaluate characteristics of Miller neonates primary objective compare time two devices.After informed consent from parents, 140 scheduled surgical...
Serum sickness is an immune-complex-mediated systemic illness that can occur after treatment with monoclonal or polyclonal antibodies such as Rituxan (Rituximab) antithymocyte globulin (Thymoglobulin), respectively. Since Rituximab now being used adjuvant for acute humoral rejection and its prevalence to cause serum comparable Thymoglobulin-associated (20% versus 27%), it should be considered a potential of treatment. In kidney transplant patients, there are no case reports where patient...
Awake fiberoptic intubation (AFOI) is the gold standard technique for managing patients with anticipated difficult airway. Conscious sedation desirable, not only to make procedure more tolerable and comfortable patient but also ensure optimal intubating conditions. Ideal regime AFOI should provide comfort, cooperation, hemodynamic stability, amnesia along maintenance of spontaneous respiration. Several sedative agents have been assessed over past two decades this purpose α2 agonists appear...
Severe perinatal depression is a significant cause of mortality and morbidity in neonates. Vitamin D levels were observed to be low mothers their neonates with hypoxic ischemic encephalopathy some studies, owing its neuroprotective properties.Primary objective was compare vitamin deficiency state full term severe healthy controls. Secondary objectives determine sensitivity specificity serum 25(OH)D<12 ng/mL predicting mortality, development encephalopathy, abnormal neurological examination...