Gurpreet Kaur Grewal

ORCID: 0000-0002-2811-1680
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About
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Research Areas
  • Drug Transport and Resistance Mechanisms
  • Pharmacological Effects and Toxicity Studies
  • Pharmacogenetics and Drug Metabolism
  • Bioenergy crop production and management
  • HIV/AIDS drug development and treatment
  • Pregnancy and Medication Impact
  • Biomedical Ethics and Regulation
  • Bioinformatics and Genomic Networks
  • Amino Acid Enzymes and Metabolism
  • Congenital Anomalies and Fetal Surgery
  • Computational Drug Discovery Methods
  • Diet and metabolism studies
  • Seed and Plant Biochemistry
  • Neuroscience and Neuropharmacology Research
  • Liver Disease and Transplantation
  • Adolescent and Pediatric Healthcare
  • Forest Biomass Utilization and Management
  • Neonatal Health and Biochemistry
  • Pluripotent Stem Cells Research
  • Biochemical and Molecular Research
  • 3D Printing in Biomedical Research
  • SARS-CoV-2 and COVID-19 Research
  • Folate and B Vitamins Research
  • Global Health Care Issues
  • Biomedical Research and Pathophysiology

Institute of Genomics and Integrative Biology
2014-2025

Academy of Scientific and Innovative Research
2017-2025

Council of Scientific and Industrial Research
2016-2025

Lovely Professional University
2022-2025

Delhi Technological University
2022

Manipal Academy of Higher Education
2022

University of Delhi
2022

B.C. Women's Hospital & Health Centre
2022

Kanya Maha Vidyalaya
2021

Addenbrooke's Hospital
1990

ABC transporters have a significant role in drug disposition and response various studies implicated their involvement epilepsy pharmacoresistance. Since genetic till now are inconclusive, we thought of investigating the xenobiotics as transcriptional modulators transporters. Here, investigated effect six antiepileptic drugs (AEDs) viz. phenytoin, carbamazepine, valproate, lamotrigine, topiramate levetiracetam, on expression function ABCB1, ABCC1, ABCC2 ABCG2 Caco2 HepG2 cell lines through...

10.3390/molecules22101484 article EN cc-by Molecules 2017-09-28

Despite the progress made in development of new antiepileptic drugs (AEDs), poor response to them is a rising concern epilepsy treatment. Of several hypotheses explaining AED treatment failure, most promising theory overexpression multidrug transporters belonging ATP-binding cassette (ABC) transporter family at blood–brain barrier. Previous data show that AEDs themselves can induce these transporters, turn affecting their own brain bioavailability. Presently, this induction and underlying...

10.1124/molpharm.122.000568 article EN Molecular Pharmacology 2022-11-22

Acute liver failure is a rare event in the newborn period yet early recognition neonatal intensive care setting essential for best outcome.Neonatal acute (NALF) distinct from older children and adults having different etiologies, presentation, unique treatment interventions.There paucity of literature regarding NALF several newly identified conditions merit discussion.Herein we report three cases who were admitted to our unit review diagnostic approach management this age group.

10.5005/jp-journals-11002-0029 article EN Newborn 2022-06-30
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