О. В. Ткачук

ORCID: 0000-0002-0599-5364
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About
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Research Areas
  • Titanium Alloys Microstructure and Properties
  • Metal and Thin Film Mechanics
  • Advanced materials and composites
  • Surface Treatment and Coatings
  • Material Properties and Applications
  • Bone Tissue Engineering Materials
  • Orthopaedic implants and arthroplasty
  • Hydrogen embrittlement and corrosion behaviors in metals
  • Chemical Synthesis and Analysis
  • Powder Metallurgy Techniques and Materials
  • Endoplasmic Reticulum Stress and Disease
  • Intermetallics and Advanced Alloy Properties
  • MXene and MAX Phase Materials
  • Protein Structure and Dynamics
  • Engineering Technology and Methodologies
  • Metal Alloys Wear and Properties
  • RNA modifications and cancer
  • Engineering and Environmental Studies
  • Aluminum Alloys Composites Properties
  • Ubiquitin and proteasome pathways
  • Anodic Oxide Films and Nanostructures
  • Material Properties and Failure Mechanisms
  • Mechanical Systems and Engineering
  • Rare-earth and actinide compounds
  • Iron-based superconductors research

University of Naples Federico II
2023-2025

National Academy of Sciences of Ukraine
2012-2024

G.V. Karpenko Physical-Mechanical Institute
2013-2024

V. Bakul Institute for Superhard Materials
2021

Warsaw University of Technology
2015

National Academy of Sciences
2009-2014

Ivanovo State Agricultural Academy named after D.K. Belyaev
2010

Additive manufacturing (AM) is a developing method and has become an advanced one for producing unique complex shaped parts. This promising of titanium alloys, as it allows to significantly reduce the costs parts compared conventional manufactured methods. In this work, effect post heat treatment on microstructure evolution corrosion resistance AM alloy in hydrochloric acid solution was studied by comparing with (wrought). As chosen selective laser melting which performed 3D Metal Tech...

10.1016/j.prostr.2024.01.030 article EN Procedia Structural Integrity 2024-01-01

Decreased proteasome activity is a hallmark of brain and retinal neurodegenerative diseases (Alzheimer's, Parkinson's diseases, glaucoma) boosting the search for molecules acting as activators. Based on hypothesis an electrostatic key code driving catalytic core particle (20S) activation by regulatory particles (RPs), we identified tetra-anionic meso-Tetrakis(4-sulphonatophenyl)-porphyrin (H2TPPS) new activator human proteasome. By means integrated approach, including bioinformatics,...

10.1080/14756366.2025.2482892 article EN cc-by-nc Journal of Enzyme Inhibition and Medicinal Chemistry 2025-04-07

Chiral natural compounds are often biosynthesized in an enantiomerically pure fashion, and stereochemistry plays a pivotal role biological activity. Herein, we investigated the significance of chirality for nature-inspired 3-Br-acivicin (3-BA) its derivatives. The three unnatural isomers 3-BA ester amide derivatives were prepared characterized their antimalarial Only (5

10.3390/molecules28073172 article EN cc-by Molecules 2023-04-03

The surface characteristics and friction behaviour of titanium Grade 2 with modified nitride (TiN, Ti2N) boride (TiB) compound layers were investigated. It was shown that during non-contact boriding in oxygen-containing medium titanium, the diffusion processes take place mainly by interscale mechanism; however, nitriding, besides traditional mechanism, grain boundary mechanism nitrogen atoms is also realized. optimal set roughness parameters (height step parameters, a combination kurtosis...

10.3390/coatings13020282 article EN Coatings 2023-01-26

A new series of tetrasubstituted pyrrole derivatives (TSPs) was synthesized based on a previously developed hypothesis their ability to mimic hydrophobic protein motifs. The resulting TSPs were endowed with significant toxicity against human epithelial melanoma A375 cells, showing IC50 values ranging from 10 27 μM, consistent the value reference compound nutlin-3a (IC50 = 15 μM). In particular, 10a μM) resulted as both most soluble and active among previous present TSPs. biological...

10.3390/molecules28104161 article EN cc-by Molecules 2023-05-18

Oxide layers on the surface of aluminum alloys D16 and AMg6 arc coatings sprayed with electrode wires made were synthesized using plasma electrolytic oxidation (PEO). The microstructure, phase composition micro-hardness PEO studied. In addition to two main phases (α-Al2O3 γ-Al2O3), a small amount metastable crystalized Al2.427O3.64 was found in their structure. A comparison wear resistance friction coefficients during tests pairs other layers, galvanic chromium coating, cast iron, steels...

10.3390/coatings14040460 article EN Coatings 2024-04-10

The corrosion behavior of oxynitrided Ti–6Al–4V alloy was investigated in the Ringer's solution (simulated body fluid) at a temperature 37°C. oxynitriding carried out by leaking controlled oxygen‐containing medium into reaction chamber final stage nitride formation. It determined that improved resistance as it provided lower current density 1.3–1.5 times and higher potential. In this paper, we analyzed double layer had increased with increase oxygen content titanium oxynitride. Its value...

10.1002/maco.201911018 article EN Materials and Corrosion 2019-07-11

Based on the analysis of known methods surface hardening aluminum alloys (chromium plating, plasma electrolytic oxidation, hard anodizing), prospects for pulsed anodizing are shown both improving functional characteristics and large-scale implementation this method. The purpose work is to show possibility improve serviceability low-strength alloy 1011 under conditions abrasive sliding wear. influence temperature phase-structural state synthesized layers, their wear resistance, tribological...

10.3390/coatings13111883 article EN Coatings 2023-11-02

Nitride coatings were formed on Ti-6Al-4V alloy by thermodiffusion treatment. The corrosion-electrochemical behaviour of with nitride I and II was investigated in physiological solutions (0.9% NaCl Tyrode's) at temperatures <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M3"><mml:mrow><mml:msup><mml:mrow><mml:mn>36</mml:mn></mml:mrow><mml:mo>∘</mml:mo></mml:msup><mml:mtext>C</mml:mtext></mml:mrow></mml:math>...

10.1155/2013/241830 article EN ISRN Corrosion 2013-02-11
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