A5000696092- Mental Health Treatment and Access
- Maternal Mental Health During Pregnancy and Postpartum
- HIV/AIDS Research and Interventions
- Family Caregiving in Mental Illness
- Schizophrenia research and treatment
- Child and Adolescent Psychosocial and Emotional Development
- Community Health and Development
- Substance Abuse Treatment and Outcomes
- Mental Health and Patient Involvement
- Migration, Health and Trauma
- Pharmacological Effects and Toxicity Studies
- Epilepsy research and treatment
- Adolescent Sexual and Reproductive Health
- Global Maternal and Child Health
- Adolescent and Pediatric Healthcare
- Health Policy Implementation Science
- HIV Research and Treatment
- HIV, Drug Use, Sexual Risk
- Digital Mental Health Interventions
- Homelessness and Social Issues
- Mobile Health and mHealth Applications
- Mental Health and Psychiatry
- HIV/AIDS drug development and treatment
- HIV-related health complications and treatments
- Disaster Response and Management
Butabika Hospital
2015-2025
Makerere University
2011-2024
Uganda Cancer Institute
2024
Child Development Center
2023
Hospital La Paz Institute for Health Research
2018
Infectious Diseases Institute
2017
World Health Organization - Uganda
2017
MRC Clinical Trials Unit at UCL
2017
University College London
2017
Ministry of Health
2015
Major depression is a common and disabling complication of the postpartum period in women. It thought to occur three times more commonly developing than developed countries.The objectives this study were determine prevalence factors associated with major among women attending peri-urban primary health care unit Kampala, Uganda, at six weeks postpartum.Five hundred fourty four centre investigated cross-sectional study. These screened using twenty five-item Self Reporting Questionnaire...
Not much is known about the risk factors of major depressive disorder (MDD) in HIV/AIDS African socio-cultural context. Therefore a study was undertaken to examine prevalence and MDD semi-urban Uganda. A cross-sectional among 618 respondents attending two HIV clinics Prevalence 8.1%. Factors associated with at univariate analysis only were female gender, family history mental illness, negative coping style, alcohol dependency disorder, food insecurity stress; not social support,...
The integration of maternal mental health into primary care has been advocated to reduce the treatment gap in low- and middle-income countries (LMICs). This study reports findings a cross-country situation analysis on services available five LMICs, inform development integrated care. was conducted districts Ethiopia, India, Nepal, South Africa Uganda, as part Programme for Improving Mental Health Care (PRIME). secondary data prevalence impact priority disorders (perinatal depression, alcohol...
There is little practical guidance on how contextually relevant mental healthcare plans (MHCPs) can be developed in low-resource settings.To describe theory of change (ToC) was used to plan the development and evaluation MHCPs as part PRogramme for Improving Mental health carE (PRIME).ToC occurred three stages: (a) a cross-country ToC by 15 PRIME consortium members; (b) country-specific ToCs 13 workshops with median (interquartile range 13-22) stakeholders per workshop; (c) review refinement...
Perinatal mental illness is a common and important public health problem, especially in low middle-income countries (LMICs). This study aims to explore the barriers facilitators, as well perceptions about feasibility acceptability of plans deliver perinatal care primary settings income, rural district Uganda. Six focus group discussions comprising separate groups pregnant postpartum women village teams eight key informant interviews were conducted local language using topic guide....
<strong>Background:</strong> Peers are people with lived experience of mental illness. Peer support is an established intervention in which peers offer to others A large proportion living severe illness receive no care. The care gap largest low- and middle-income countries, detrimental effects on individuals societies. global shortage human resources for health important driver the gap. under-used resource health. <strong>Objectives:</strong> To describe rationale methodology international...
This guidance details the needs of children, and qualities parenting that meet those needs. Parental mental disorders can damage foetus during pregnancy through action drugs, prescribed or abused. Pregnancy puerperium exacerbate initiate illness in susceptible women. After their birth, children may suffer from social disadvantage associated with severe illness. The parents (depending on disorder, its severity persistence) have intermittent prolonged difficulties parenting, which sometimes...
Suicidality in HIV/AIDS is not only a predictor of future attempted suicide and completed suicide, it also associated with poor quality life adherence antiretroviral therapy. This paper examines the prevalence correlates suicidality African nation Uganda. A cross-sectional study was undertaken among 618 respondents attending two HIV clinics semi-urban structured questionnaire used to collect data on demographic, social, psychological clinical factors. Correlates were assessed using...
The Theory of Change (ToC) approach has been used to develop and evaluate complex health initiatives in a participatory way high income countries. Little is known about its use mental care plans low middle countries where services remain inadequate.ToC workshops were held as part formative phase the Programme for Improving Mental Health Care (PRIME) order 1) structured logical evidence-based ToC map basis plan each district; (2) contextualise plans; (3) obtain stakeholder buy-in Ethiopia,...
Cross-resistance after first-line antiretroviral therapy (ART) failure is expected to impair activity of nucleoside reverse-transcriptase inhibitors (NRTIs) in second-line for patients with HIV, but evidence the effect cross-resistance on virological outcomes limited. We aimed assess association between activity, predicted by resistance testing, NRTIs used and treatment infected HIV.We did an observational analysis additional data from a published open-label, randomised trial ART (EARNEST)...
Background. The prevalence of depression in rural Ugandan communities is high and yet detection treatment the primary care setting suboptimal. Short valid screening measures may improve depression. We describe validation Luganda translated nine- two-item Patient Health Questionnaires (PHQ-9 PHQ-2) as tools for two facilities Eastern Uganda. Methods. A total 1407 adult respondents were screened consecutively using nine-item PHQ. Of these 212 randomly selected to respond Mini International...
Evaluations to objectively assess minimum competency are not routinely implemented for training and supervision in global mental health. Addressing this gap assessment is crucial safe effective health service integration primary care. To explore competency, study describes a program 206 workers Uganda, Liberia, Nepal humanitarian settings impacted by political violence, Ebola, natural disasters. Health were trained the World Organization's Gap Action Programme (mhGAP). demonstrated changes...
Uganda has one of the highest per capita alcohol consumption rates in sub-Saharan Africa. However, prevalence use disorders (AUD) remains unknown many areas, especially rural districts. This study aimed to estimate and disorder among men, describe distribution drinking intensity, men Kamuli District, Uganda. Men attending primary care clinics District were consecutively interviewed a facility-based cross-sectional study, separate group population-based study. In both studies administered...
Objectives To estimate the proportion of adult primary care outpatients who are clinically detected and initiate treatment for depression alcohol use disorder (AUD) in low-income middle-income country (LMIC) settings. Design Five cross-sectional studies. Setting Adult outpatient services 36 healthcare facilities Sodo District, Ethiopia (9 facilities); Sehore India (3); Chitwan Nepal (8); Dr Kenneth Kaunda South Africa Kamuli Uganda (13). Participants Between 760 1893 adults were screened...
Peer support is an established intervention involving a person recovering from mental illness supporting others with illness. under-used resource in global health. Building upon comprehensive formative research, this study will rigorously evaluate the impact of peer at multiple levels, including service user outcomes (psychosocial and clinical), worker (work role empowerment), (cost-effectiveness return on investment), implementation (adoption, sustainability organisational...
Abstract Background Alcohol use is part of many cultural, religious and social practices, provides perceived pleasure to users. In societies, alcoholic beverages are a routine the landscape for in population. Relatively low rates were reported Use Disorders (AUD) community-based survey facility detection conducted study site contrary findings earlier formative studies where alcohol was be major health problem. The aim this understand reasons under-reporting rate AUDs, exploring societal...
Background Peer support in mental health is a low-threshold intervention with increasing evidence for enhancing personal recovery and empowerment of persons living severe conditions. As peer spreads globally, there growing need training programmes that work well different contexts cultures. This study evaluates the applicability transferability implementing manualised multi-national programme workers called UPSIDES from perspective local stakeholders high-, middle-, low-income countries....
Background Evidence is needed for the integration of mental health into primary care advocated by national sector strategic investment plan in Uganda. Aims To describe processes developing a district healthcare (MHCP) rural Uganda that facilitates care. Method Mixed methods using situational analysis, qualitative studies, theory change workshops and partial piloting at two levels informed MHCP. Results A MHCP was developed with packages to facilitate organisational, facility community...
The HIV/AIDS infection is common in sub-Saharan Africa and associated with psychological neuro- cognitive impairment. These conditions, however, remain largely unrecognized. In this study we aimed to determine the prevalence of probable HIV dementia (PHD) an clinic population Uganda delineate factors such impairment these positive individuals. Six hundred eighty attendees were surveyed a cross sectional study. PHD was assessed using International Dementia Scale (IHDS). Standardized measures...
Abstract Background The Programme for Improving Mental Health Care (PRIME) sought to implement mental health care plans (MHCP) four priority disorders (depression, alcohol use disorder, psychosis and epilepsy) into routine primary in five low- middle-income country districts. impact of the MHCPs on disability was evaluated through establishment disorder treatment cohorts. This paper describes methodology these PRIME Methods One cohort each recruited across some or all districts: Sodo...
Abstract Background Perinatal depression is associated with poor outcomes related to HIV care adherence, maternal functioning, and early child development. We examined whether the M-DEPTH (Maternal Depression Treatment in HIV) model—including antidepressant therapy individual problem-solving therapy—and alleviation would affect improvement each of these outcome domains. Methods A sample 354 pregnant women living (WLH) at least mild depressive symptoms (177 intervention usual control arms)...
Millions of HIV-infected people worldwide receive antiretroviral therapy (ART) in programmes using WHO-recommended standardised regimens. Recent WHO guidelines recommend a boosted protease inhibitor plus raltegravir as an alternative second-line combination. We assessed whether this treatment option offers any advantage over the standard two nucleoside reverse-transcriptase inhibitors (NRTIs) combination after 144 weeks follow-up typical programme settings.
Limited knowledge exists to inform the selection and introduction of locally relevant, feasible, effective mental health interventions in diverse socio-cultural contexts systems. We examined stakeholders' perspectives on health-related priorities, help-seeking behaviors, existing resources guide development a maternal component for integration into non-specialized care Soroti, eastern Uganda.We employed rapid ethnographic methods (free listing ranking; semi-structured interviews; key...