A5083731881- Acute Ischemic Stroke Management
- Genomics and Phylogenetic Studies
- Microbial Community Ecology and Physiology
- Bacteriophages and microbial interactions
- Animal Virus Infections Studies
- Regional Economics and Spatial Analysis
- Pharmaceutical and Antibiotic Environmental Impacts
- Methane Hydrates and Related Phenomena
- Gut microbiota and health
- Bacillus and Francisella bacterial research
- Advanced oxidation water treatment
- Water Treatment and Disinfection
- Nuclear and radioactivity studies
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- RNA and protein synthesis mechanisms
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Venous Thromboembolism Diagnosis and Management
- Economic theories and models
- Rural development and sustainability
- Service and Product Innovation
- Cross-Border Cooperation and Integration
- Psidium guajava Extracts and Applications
- Economic Growth and Productivity
- Plant responses to elevated CO2
MRIGlobal
2017-2025
University of Delaware
2014-2016
University of Wollongong
2016
Sanford Burnham Prebys Medical Discovery Institute
2014
University of Cincinnati
2013
University of Providence
2005-2006
Argonne National Laboratory
1990
University of Illinois System
1950-1983
University of Illinois Urbana-Champaign
1958-1977
United States Department of the Army
1963
Abstract The future of infectious disease surveillance and outbreak response is trending towards smaller hand-held solutions for point-of-need pathogen detection. Here, samples Culex cedecei mosquitoes collected in Southern Florida, USA were tested Venezuelan Equine Encephalitis Virus (VEEV), a previously-weaponized arthropod-borne RNA-virus capable causing acute fatal encephalitis animal human hosts. A single 20-mosquito pool positive VEEV by quantitative reverse transcription polymerase...
Predicting phenotypic properties of a virus directly from its sequence data is an attractive goal for viral epidemiology. Here, we focus narrowly on the Orthocoronavirinae clade and demonstrate models that are powerfully predictive human-pathogen phenotype with >86% average precision >99% recall withheld test set groups, using only Orf1ab codon frequencies. We show alternative examples other coding sequences feature representations do not perform well discuss what distinguishes...
Predicting phenotypic properties of a virus directly from its sequence data is an attractive goal for viral epidemiology. Here, we focus narrowly on the Orthocoronavirinae clade and demonstrate models that are powerfully predictive human-pathogen phenotype with 76.74% average precision 85.96% recall withheld test set groups, using only Orf1ab codon frequencies. We show alternative examples other coding sequences feature representations do not perform well discuss what distinguishes...
Journal Article The Wheatstone Bridge Porometer Get access O. V. S. HEATH, HEATH Research Institute of Plant Physiology, Imperial College Science and TechnologyLondon, S.W. 7 Search for other works by this author on: Oxford Academic PubMed Google Scholar J. RUSSELL Experimental Botany, Volume 2, Issue 1, 1951, Pages 111–116, https://doi.org/10.1093/jxb/2.1.111 Published: 01 March 1951
Abstract Pavilion Lake in British Columbia, Canada, is home to modern‐day microbialites that are actively growing at multiple depths within the lake. While microbialite morphology changes with depth and previous isotopic investigations suggested a biological role formation of these carbonate structures, little known about their microbial communities. Microbialite samples acquired through Research Project (PLRP) were first investigated for phototrophic populations using Cyanobacteria...
Patients with congenital disorder of glycosylation (CDG), type Ib (MPI-CDG or CDG-Ib) have mutations in phosphomannose isomerase (MPI) that impair and lead to stunted growth, liver dysfunction, coagulopathy, hypoglycemia, intestinal abnormalities. Mannose supplements correct hypo-glycosylation most symptoms by providing man-nose-6-P (Man-6-P) via hexokinase. We generated viable Mpi hypomorphic mice residual enzymatic activity comparable patients, but surprisingly, these appeared completely...
Rapid, specific, and sensitive identification of microbial pathogens is critical to infectious disease diagnosis surveillance. Classical culture-based methods can be applied a broad range but have long turnaround times. Molecular methods, such as PCR, are time-effective not comprehensive may detect novel strains. Metagenomic shotgun next-generation sequencing (NGS) promises specific characterization any pathogen (viruses, bacteria, fungi, protozoa) in less biased way. Despite its great...
Studies of subsurface microorganisms have yielded few environmentally relevant isolates for laboratory studies. In order to address this lack cultivated microorganisms, we initiated several enrichments on sediment and underlying basalt samples from North Pond, a basin ringed by outcrops an oligotrophic water-column west the Mid-Atlantic Ridge at 22°N. contrast anoxic enrichments, growth was observed in aerobic, heterotrophic IODP Hole U1382B 4 68 m below seafloor (mbsf). These depths,...
ABSTRACT: Context: Rapid diagnosis and treatment of ischemic stroke can lead to improved patient outcomes. Hospitals in rural frontier counties, however, face unique challenges providing diagnostic services for acute stroke. Purpose: The aim this study was assess the availability key technology programs evaluation Montana northern Wyoming. Methods: In 2004, hospital medical directors or their designees were mailed a survey about technology, programs, personnel care. Findings: Fifty‐eight 67...
Accurate, high-confidence data is critical for assessing potential biothreat incidents. In a event, false-negative and -positive results have serious consequences. Worst case scenarios can result in unnecessary shutdowns or fatalities at an exorbitant monetary psychological cost, respectively. Quantitative PCR assays agents of interest been successfully used routine biosurveillance. Recently, there has increased impetus adoption amplicon sequencing (AS) biosurveillance because it enables...
ABSTRACT: Purpose: To assess stroke knowledge and practice among frontier urban emergency medical services (EMS) providers to evaluate the need for additional prehospital training opportunities in Montana. Methods: In 2006, a telephone survey of representative sample EMS was conducted Respondents were stratified into 2 groups: those working counties. Findings: Compared from counties, counties significantly more likely be older (mean age 44.7 vs 40.1 years), have fewer personnel their service...
The aim of this study was to evaluate the intrarater and interrater reliability handheld goniometry compared image capture (IMC) in assessment joint position sense (JPS) healthy participants. A repeated-measures observational undertaken with 36 asymptomatic university students both genders aged 18–45 years. JPS knee assessed by two assessors over sessions (1 week interval) using IMC methods. at four target flexion angles. Intrarater absolute error (AE), relative (RE) intraclass correlation...
ABSTRACT Metagenomics is emerging as an important tool in biosurveillance, public health, and clinical applications. However, ease-of-use for execution data analysis remains a barrier-of-entry to the adoption of metagenomics applied health forensics settings. In addition, these venues often have more stringent requirements reporting, accuracy, precision than traditional ecological research role technology. Here, we present PanGIA ( Pan - G enomics I nfectious A gents), novel bioinformatics...
ABSTRACT Background Social return on investment (SROI) may present a method for demonstrating the social value of healthcare interventions. It has not previously been measured in musculoskeletal (MSK) physiotherapy but is being used procurement and performance management services. The aim study was to measure SROI one provider MSK United Kingdom's National Health Service (NHS). Methods A retrospective single arm online survey‐based service evaluation carried out calculate an NHS adult using...