E. Guffanti

ORCID: 0000-0002-0624-4941
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About
Contact & Profiles
Research Areas
  • Respiratory Support and Mechanisms
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Heart Failure Treatment and Management
  • Asthma and respiratory diseases
  • Respiratory and Cough-Related Research
  • Cardiac electrophysiology and arrhythmias
  • Blood Pressure and Hypertension Studies
  • Pediatric health and respiratory diseases
  • Nutrition and Health in Aging
  • Health Systems, Economic Evaluations, Quality of Life
  • Cardiovascular and exercise physiology
  • Intensive Care Unit Cognitive Disorders
  • Neonatal Respiratory Health Research
  • Long-Term Effects of COVID-19
  • Pancreatitis Pathology and Treatment
  • Cardiac Valve Diseases and Treatments
  • Pharmaceutical studies and practices
  • Cardiovascular Syncope and Autonomic Disorders
  • Pharmacological Effects and Assays
  • Cardiovascular Function and Risk Factors
  • Hormonal Regulation and Hypertension
  • Family and Patient Care in Intensive Care Units
  • Frailty in Older Adults
  • Pharmaceutical Practices and Patient Outcomes
  • Pulmonary Hypertension Research and Treatments

University of Pavia
2022

Istituto Nazionale di Riposo e Cura per Anziani
2006-2020

Istituti di Ricovero e Cura a Carattere Scientifico
2011-2020

Associazione Italiana Pneumologi Ospedalieri
2016

National Research Centre
2009-2010

United States Nuclear Regulatory Commission
2006

Fondazione Salvatore Maugeri
2001

University of Milan
1996

University of Ottawa
1995

Queen's University
1995

Due to the exponential growth of number subjects affected by coronavirus disease 2019 (COVID-19), entire Italian health care system had respond promptly and in a very short time with need semi-intensive intensive units. Moreover, trained dedicated COVID-19 teams consisting physicians were coming from different specialties (intensivists or pneumologists infectiologists), while respiratory therapists nurses have been recruited work on without rest. However, due still limited evolving knowledge...

10.1159/000508399 article EN other-oa Respiration 2020-01-01

There is a need of consensus about the pulmonary rehabilitation (PR) in patients with COVID-19 after discharge from acute care. To facilitate knowledge evidence and its translation into practice, we developed suggestions based on experts’ opinion. A steering committee identified areas questions sent to experts. Other international experts participated RAND Delphi method reaching proposing further suggestions. Strong agreement was defined when mean >7 (1 = no 9 maximal agreement)....

10.4081/monaldi.2020.1444 article EN cc-by-nc Monaldi Archives for Chest Disease 2020-06-23

We designed a prospective multicenter randomized controlled study in three long-term weaning units (LWU) to evaluate which protocol, inspiratory pressure support ventilation (PSV) or spontaneous breathing trials (SB), is more effective patients with chronic obstructive pulmonary disease (COPD) requiring mechanical for than 15 d. Fifty-two of 75 patients, failing an initial T-piece trial at admission, were randomly assigned PSV SB (26 both groups). No significant difference was found success...

10.1164/ajrccm.164.2.2008160 article EN American Journal of Respiratory and Critical Care Medicine 2001-07-15

Thyme essential oil and thymol have antimicrobial, antifungal antioxidant activities. Their activity has been studied almost exclusively by means of chemical testing in order to be able use it for food preservation purposes. The aim this luminol amplified chemiluminescence (LACL) study was investigate whether can interfere with the production reactive oxygen species, nitric oxide oxide-derived peroxynitrite released human neutrophils after activation fMLP PMA without addition L-arginine...

10.1159/000089719 article EN Pharmacology 2005-11-15

Home care for patients under home mechanical ventilation (HMV) may cause dramatic physical and economic burden in addition to the of time on family/caregivers health service (HCS) with difficult resource allocation decision-making. Our aims were: 1. To identify conditions causing major managing HMV according family payer's perspectives related characteristics disease, dependency accessibility; 2. find, if any, differences among diseases.A questionnaire was sent eight pulmonary centres...

10.4081/monaldi.2007.485 article EN cc-by-nc Monaldi Archives for Chest Disease 2016-02-03

Background: Body composition has been shown to be correlated with physical performance, but data in older persons diverse chronic diseases are lacking.Objective: We aimed at investigating the associations of body gait speed and nutritional status people different stages obstructive pulmonary disease (COPD).Design, setting subjects: Cross-sectional analysis from Pulmonary Rehabilitation Geriatric Unit INRCA Casatenovo, Italy including 132 consecutively admitted COPD patients (mean age: 75...

10.1093/ageing/aft196 article EN Age and Ageing 2013-12-22

Abstract Adhesion is an important starting event in the pathogenesis of bacterial infection because microorganisms must first adhere to host tissue order multiply and create a colony or colonies before specific symptoms allow disease process be detected. This particularly true case female urogenital infections, including urinary tract vaginosis vaginitis. Thymol component thyme essential oil, which has been reported possess interesting antimicrobial effects on various microorganisms;...

10.1080/10412905.2006.9699140 article EN Journal of Essential Oil Research 2006-07-01

<h3>BACKGROUND:</h3> Self-management education is associated with improvement in quality of life and reduction hospital admissions. Nevertheless, the data are insufficient to formulate clear recommendations regarding type content programs for COPD patients, few available on knowledge disease itself. <h3>OBJECTIVE:</h3> To test level patients9 their therapy at baseline after an educational program (COPD-EP); feasibility structured sessions; influence clinical status (degree severity disease,...

10.4187/respcare.01697 article EN Respiratory Care 2013-01-27

Activated neutrophils can release superoxide anion and nitric oxide (NO), which subsequently combine with each other to yield peroxynitrite anions, powerful harmful oxidants that preferentially mediate the oxidation of thiol groups in proteins non-protein molecules. These play a direct role inflammatory process chronic obstructive pulmonary disease asthma by increasing number macrophages induce self-sustaining phlogogenic loop. Budesonide (BUD) erdosteine (a muco-active drug which, after...

10.1159/000084295 article EN Pharmacology 2005-01-01

Background: A fast and simple tool is needed to test for the risk of mortality rehospitalization in older patients. Objective: The aim this study was construct validate a prognostic index using specific items from Comprehensive Geriatric Assessment (CGA) large population hospitalized adults. Method: This prospective 24-month follow-up period, between 2005 2008 3,043 elderly patients (mean age, 81 ± 6) discharged three acute geriatric wards Marche region Italy. Baseline predictors...

10.1089/rej.2011.1171 article EN Rejuvenation Research 2011-08-25

Recurrence rate and the perioperative outcome evaluation through laparoscopic approach for ventral (primary incisional) hernia repair.A retrospective of a series patients treated minimally invasive was performed. A standardized surgical technique adopted. All were evaluated clinical follow-up.From July 2004 to June 2011, 150 videolaparoscopic repairs The median follow-up 40 months. One recurrence (0.7%) detected after 55 intraoperative postoperative complication 2.6% (1 conversion open...

10.1097/sle.0b013e31828f6b81 article EN Surgical Laparoscopy Endoscopy & Percutaneous Techniques 2014-03-31

Many lung disorders are characterized by airway inflammation involving the recruitment of inflammatory cells, and leading to release oxidant mediators. The overproduction superoxide anion (O&lt;sub&gt;2&lt;/sub&gt;&lt;sup&gt;–&lt;/sup&gt;DELETE) nitric oxide (NO) during respiratory bursts neutrophils leads production peroxynitrite, a highly damaging with an important role in loop causing hyper-reactivity diseases like asthma. aim this study was investigate vitro effects 1-hour incubation...

10.1159/000088623 article EN Pharmacology 2005-01-01

Nocturnal hypoxemia occurs commonly in patients with chronic obstructive pulmonary disease (COPD). Because hypertension and cardiac arrhythmias are associated this phenomenon, the detection treatment of nocturnal should be part management COPD patients. The ability to predict by evaluating an awake patient would desirable economically logistically because continuous oximetry is not widely available it costly labor intensive. We sought determine whether precise enough clinically useful...

10.1016/0003-9993(94)90030-2 article EN cc-by-nc-nd Archives of Physical Medicine and Rehabilitation 1994-03-01
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