A5101776276- Zeolite Catalysis and Synthesis
- Hydraulic and Pneumatic Systems
- Mesoporous Materials and Catalysis
- Catalysis and Hydrodesulfurization Studies
- Advanced Condensed Matter Physics
- Cavitation Phenomena in Pumps
- Cell Adhesion Molecules Research
- Catalysis and Oxidation Reactions
- Transition Metal Oxide Nanomaterials
- Membrane Separation and Gas Transport
- Spectroscopy and Laser Applications
- Cyclone Separators and Fluid Dynamics
- Inorganic Chemistry and Materials
- Heat Transfer Mechanisms
- Monoclonal and Polyclonal Antibodies Research
- Calibration and Measurement Techniques
- Immune cells in cancer
- Oil and Gas Production Techniques
- Semiconductor materials and devices
- Physics of Superconductivity and Magnetism
- Analytical Chemistry and Chromatography
- Anodic Oxide Films and Nanostructures
- Semiconductor materials and interfaces
- Microwave-Assisted Synthesis and Applications
- Crystal Structures and Properties
The University of Tokyo
2009-2025
Saitama Prefectural Kumagaya Girls High School
2020-2024
Tokyo Denki University
2022-2024
Japan Association for Development of Community Medicine
2022-2024
University of Tsukuba
2024
Sophia University
2016-2021
Furukawa Electric (Japan)
2015-2019
Shizuoka Institute of Science and Technology
2000-2019
Tohoku University
1982-2018
Canon Medical Systems Corporation (Japan)
2018
Adipose tissue is an endocrine and energy storage organ composed of several different cell types, including mature adipocytes, stromal cells, endothelial a variety immune cells. aging contributes to the pathogenesis metabolic dysfunction likely induced by crosstalk between adipose progenitor cells (APCs) but underlying molecular mechanisms remain largely unknown. In this study, we revealed biological role p16high senescent APCs, investigated each type in aged white tissue. We performed...
The tumor microenvironment (TME) encompasses various cell types, blood and lymphatic vessels, noncellular constituents like extracellular matrix (ECM) cytokines. These intricate interactions between cellular components contribute to the development of a malignant TME, such as immunosuppressive, desmoplastic, angiogenic conditions, formation niche for cancer stem cells, but there is limited understanding specific subtypes stromal cells involved in this process. Here, we utilized p16-Cre ERT2...
DNA hypomethylating agents (HMAs) are used for the treatment of myeloid malignancies, although their therapeutic effects have been unsatisfactory. Here we show that CRISPR-Cas9 screening reveals knockout topoisomerase 1-binding arginine/serine-rich protein (TOPORS), which encodes a ubiquitin/SUMO E3 ligase, augments efficacy HMAs on leukemic cells with little effect normal hematopoiesis, suggesting TOPORS is involved in resistance to HMAs. incorporated into and trap methyltransferase-1...
A comprehensive characterization of various carbon nanotube (CNT) yarns provides insight for producing high-performance CNT as well a useful guide to select the proper yarn specific application. Herein we systematically investigate correlations between physical properties six produced by three spinning methods, and their structures constituent CNTs. The electrical conductivity increases in all regardless method effective length CNTs density increase. On other hand, tensile strength shows...
The effect of the substitution various ions on metal–insulator (MI) transition at 170 K in 2 V 8 O 16 has been investigated. Both Rb and Ti form complete solid solution systems: 2- x 8- y , respectively. for or splits into two transitions: high-temperature is a first-order MI from tetragonal structure to structure, low-temperature second-order monoclinic structure. In former terminates an around 220 while latter disappears > 0.6. both transitions disappear 0.5. Cr also results similar...
Although a short-term blockade of intercellular adhesion molecule-1 (ICAM-1) and leukocyte function-associated antigen-1 (LFA-1) allows induction specific tolerance to solid organs, their effect on primary skin allografts is not yet known. Effects anti-ICAM-1 anti-LFA-1 monoclonal antibodies (mAb) allograft survival were investigated. Recipient mice treated with either combination mAbs or control mAb for the first 22 days. The BALB/c in C3H/He recipient was prolonged. Subsequently, MHC class...
We propose tabular two-dimensional correlation spectroscopy analysis for extracting features from multifaceted characterization data, essential understanding material properties. This method visualizes similarities and phase lags in structural parameter changes through heatmaps, combining hierarchical clustering asynchronous correlations. applied the proposed to data sets of carbon nanotube (CNT) films annealed at various temperatures revealed complexity their structures, which include...
While cysteine (CysSH) is known to be exported into the extracellular space, its biological significance not well understood. The present study examined movement of CysSH using stable isotope-labeled cystine (CysSSCys), which transported cells and reduced CysSH. Exposure HepG2 100 µM CysSSCys resulted in 70 labeled cell medium 1 h after exposure. When was collected incubated with either hydrogen peroxide (H2O2) or atmospheric electrophiles, such as 1,2-naphthoquinone, 1,4-naphthoquinone...
Reaction of a diiron(III) complex having xylta4- ligand (N,N,N',N'-m-xylylenediamine tetraacetate) with H2O2 resulted in regioselective hydroxylation the m-xylyl linker. The reaction mimics self-hydroxylation phenylalanine side chain found for ribonucleotide reductase (R2-W48F/D84E).
The luminescence spectrum of PbI 2 is measured in the excitation below fundamental absorption edge at low temperatures. Phonon-assisted bands appear on Stokes side energy and these are considered to be associated with recombination a donor-acceptor pair accompanied emission optical acoustic phonons. Also anti-Stokes side, strong observed. It led conclusion that luminescences originate from radiative between an acceptor hole generated by light electron donor shallower than neutralized light.
Platelet aggregometry by the laser light scattering (LS) method is sufficiently sensitive to detect small platelet aggregates that form spontaneously in vitro absence of agonists. aggregation without agonists named spontaneous (SPA). Since SPA has been suggested be associated with various thrombotic diseases, it essential measure and establish a standard range values. In this study, we measured 167 healthy subjects LS attempted clarify factors influencing SPA, including blood collection...
Although fusion of somatic cells with embryonic stem (ES) has been shown to induce reprogramming, single-cell level details the transitory phenotypic changes that occur during fusion-based reprogramming are still lacking. Our group previously reported on technique one-to-one electrofusion via micro-slits in a microfluidic platform. In this study, we focused developing novel air-lock patterning for creating localized adhesion zones around cell localization and real-time imaging post events...
In a molecular beam sampling process, if the stagnation gas is mixture, heavier species are concentrated onto axis of beam, while lighter ones diffused away from it. This phenomenon generally called "mass separation." Mass separation caused mainly by three phenomena: (1) pressure diffusion, (2) Mach-number focusing and (3) skimmer interference. Pressure diffusion has already been analyzed Sherman. present work, mass for binary mixture Ar He was experimentally measured means beam-mass filter...