A5065061740- Mycorrhizal Fungi and Plant Interactions
- Herpesvirus Infections and Treatments
- Plant and soil sciences
- Seedling growth and survival studies
- Soil Carbon and Nitrogen Dynamics
- Legume Nitrogen Fixing Symbiosis
- Poxvirus research and outbreaks
- Plant-Microbe Interactions and Immunity
- Animal Virus Infections Studies
- Fungal Biology and Applications
- Plant nutrient uptake and metabolism
- Virus-based gene therapy research
- Biochemical and biochemical processes
- Growth and nutrition in plants
- Agroforestry and silvopastoral systems
- Cytomegalovirus and herpesvirus research
- Soil Management and Crop Yield
- Banana Cultivation and Research
- Immunotherapy and Immune Responses
- Agricultural and Food Production Studies
- Forest ecology and management
- Invertebrate Taxonomy and Ecology
- interferon and immune responses
- Postharvest Quality and Shelf Life Management
- Toxin Mechanisms and Immunotoxins
Universidad Nacional de Colombia
2013-2023
Fundación Santa Fe de Bogotá
2022-2023
Universidad Pontificia Bolivariana
2022
Colombian Corporation for Agricultural Research - AGROSAVIA
2016-2020
University of California, Irvine
2004-2016
Pascual Bravo Institution University
2015
Oregon State University
2008
University of Hawaii System
2003
Cedars-Sinai Medical Center
2001-2002
University of California, Irvine Medical Center
2002
ABSTRACT The herpes simplex virus type 1 (HSV-1) latency-associated transcript (LAT) is the only HSV-1 gene abundantly expressed throughout latency. LAT null mutants have a significantly reduced reactivation phenotype. LAT's antiapoptosis activity major factor involved in supporting wild-type During latency, some ganglionic neurons are surrounded by CD8 T cells, and it has been proposed that these cells help maintain latency suppressing viral reactivations. Surprisingly, despite injection of...
Alkaline desert soils are high in insoluble calcium phosphates but deficient soluble orthophosphate (Pi) essential for plant growth. In this extreme environment, one adaptive strategy could involve specific associations between roots and mineral phosphate solubilizing (MPS) bacteria. The most efficient MPS phenotype Gram-negative bacteria results from extracellular oxidation of glucose to gluconic acid via the quinoprotein dehydrogenase. A unique bacterial population isolated Helianthus...
ABSTRACT After ocular herpes simplex virus type 1 (HSV-1) infection, the travels up axons and establishes a lifelong latent infection in neurons of trigeminal ganglia. LAT (latency-associated transcript), only known viral gene abundantly transcribed during HSV-1 neuronal latency, is required for high levels reactivation. The function responsible this reactivation phenotype not known. Recently, we showed that can block programmed cell death (apoptosis) ganglion vivo tissue culture cells vitro...
An investigation was carried out to assess the role that P solubilizing micro-organisms play in nutrition of mycorrhizal and mycorrhiza-free Leucaena leucocephala (L am.). Soil microorganisms able solubilize rock phosphate were isolated from rhizosphere L. naturally growing on three different soils Hawaii. The isolates screened for their ability culture medium. highest activity observed with one fungal isolates, which identified as Mortierella sp. It multiplied further evaluated or without...
Following ocular herpes simplex virus 1 (HSV-1) infection of C57BL/6 mice, HSV-specific (HSV-gB(498-505) tetramer(+)) CD8(+) T cells are induced, selectively retained in latently infected trigeminal ganglia (TG), and appear to decrease HSV-1 reactivation. The latency-associated transcript (LAT) gene, the only viral gene that is abundantly transcribed during latency, increases Previously we found latency with strain McKrae-derived viruses, more total TG resident CD8 expressed markers...
A series of in vitro experiments were carried out to evaluate the effectiveness a phosphorus-solubilizing fungus desorb phosphate (Pi) from soil samples differing their Pi-sorption capacity. The results indicate that Mortierella sp. was effective desorbing Pi all tested by producing oxalic acid, and its varied among orders. influenced capacity, which could be used as predictor microbes increase soluble via desorption soils. most pronounced Mollisol followed an Oxisol, Ultisol, then three...
In the tropical drylands of Colombia, soils subjected to traditional systems livestock production are severely degraded and depleted plant nutrients. Multistrata silvopastoral viable alternatives improve production; however, it is unknown whether these can reduce negative environmental impacts on soil quality. The objective this study was evaluate effects 13-year-old multistrata quality parameters in Sinu River Valley, Colombia. results show that trees increased or maintained pH values...
An experiment was conducted to evaluate the individual and combined effects of treatment with phosphate solubilizing fungus Mortierella sp. arbuscular mycorrhizal Rhizoglomus fasciculatum on plant growth uptake plantlets avocado (Persea americana Mill. cv. ‘Hass’) grown in a nursery. A completely randomized test design used. Treatments consisted inoculations R. at two concentrations (10 6 10 8 CFU·mL −1 ), results were compared an uninoculated control. The height, shoot dry mass,...
A greenhouse experiment was conducted to determine the effects of a phosphate-solubilizing fungus (Mortierella sp.) and an arbuscular mycorrhizal (Glomus fistulosum (Skou Jakobsen)) in enhancing plant Pi uptake growth Leucaena leucocephala (Lam.) grown Oxisol fertilized with graded amounts rock phosphate (RP). For this purpose, surface soil sample four levels Huila RP (P = 0, 150, 300, 600 mg·kg −1 ) inoculated none, one, or both fungi. In unfertilized soil, leucaena plants grew poorly there...
Litter decomposition is a major process in nutrient recycling, despite that few studies have considered this soil fertility management. The aim of study was to evaluate the effect litter and its inoculation with fungus Mortierella sp. on parameters Andisols cultivated avocado cv. Hass. Litterbags containing leaves either uninoculated or inoculated were distributed around trees. As control not allowed accumulate surface. Eighteen months later samples collected just below litterbags sites....
ABSTRACT Persistent pathogens, such as herpes simplex virus 1 (HSV-1), have evolved a variety of immune evasion strategies to avoid being detected and destroyed by the host's system. A dynamic cross talk appears occur between HSV-1 latency-associated transcript (LAT), only viral gene that is abundantly transcribed during latency, CD8 + T cells reside in latently infected human rabbit trigeminal ganglia (TG). The reactivation phenotype TG are with wild-type or LAT-rescued mutant (i.e., LAT...
ABSTRACT Following primary ocular infection, herpes simplex virus type 1 (HSV-1) establishes a lifelong latent infection in sensory neurons of the trigeminal ganglia. Latency-associated transcript (LAT), only known viral gene abundantly transcribed during HSV-1 neuronal latency, is required for high levels reactivation. Recently we showed that three different mutants do not alter LAT promoter but contain deletions within 5′ end affect virulence (G. C. Perng et al., J. Virol. 75:9018-9028,...
ABSTRACT The latency-associated transcript (LAT) is essential for the wild-type herpes simplex virus type 1 (HSV-1) high-reactivation phenotype since LAT − mutants have a low-reactivation phenotype. We previously reported that can decrease apoptosis and proposed this activity involved in LAT's ability to enhance HSV-1 reactivation first 20% of primary 8.3-kb sufficient enhancing decreasing apoptosis, supporting proposal. For study, we constructed an mutant expresses baculovirus antiapoptosis...
ABSTRACT Most blinding ocular herpetic disease is due to reactivation of herpes simplex virus 1 (HSV-1) from latency rather than primary acute infection. No vaccine currently available for use in humans. In this study, we used the HLA-A*02:01 transgenic (HLA Tg) rabbit model assess efficacy a therapeutic based on HSV-1 gD epitopes that are recognized mainly by CD8 + T cells “naturally” protected HLA-A*02:01-positive, HSV-1-seropositive healthy asymptomatic (ASYMP) individuals (who have never...
Tropical soils are characterized by acidity and poor plant nutrient availability, limiting their agricultural productivity. These commonly amended with lime, but its low solubility impairs effectiveness to enhance soil fertility. The use of gypsum has gained attention among farmers due higher mobility in the soil, local accessibility, price. Therefore, this study was conducted determine effects Agricultural Gypsum (AG) addition on ten Colombian acid that had fertility contrasting physical...