- Advanced Fluorescence Microscopy Techniques
- Photoacoustic and Ultrasonic Imaging
- Optical Coherence Tomography Applications
- Spectroscopy Techniques in Biomedical and Chemical Research
- Parallel Computing and Optimization Techniques
- Biosensors and Analytical Detection
- Nanoplatforms for cancer theranostics
- Network Packet Processing and Optimization
- Interconnection Networks and Systems
- Protein Interaction Studies and Fluorescence Analysis
- Cell Image Analysis Techniques
Hanyang University
2010-2023
Anyang University
2023
Background: Simplified hematoxylin and eosin (H&E) staining followed by cryo-sectioning enables rapid identification of cancerous tissue within the procedure room during Mohs micrographic surgery. Yet, a faster evaluation method is desirable as protocol requires physically sectioning after freezing, which leads to prolonged time along with frozen artifacts that may occur in sectioning.
Two-photon microscopy (TPM) is an attractive biomedical imaging method due to its large penetration depth and optical sectioning capability. In particular, label-free autofluorescence offers various advantages for biological samples. However, relatively low intensity of leads signal-to-noise ratio (SNR), causing practical challenges this study, we present TPM using a pulse picker utilize repetition rate femtosecond pulsed laser increase the peak power excitation source leading higher...
Multimodal nonlinear microscopy has been widely applied in biology and medicine due to its relatively deep penetration into tissue label-free manner. However, current multimodal systems require the use of multiple sources detectors, leading bulky, complex, expensive systems. In this Letter, we present a novel method using single light source detector for imaging biological samples. Using photonic crystal fiber, pulse picker, multimode fibers, our developed system successfully acquired images...
With the development of advanced and minimally invasive surgical techniques, in view functional cosmetic aspects, need for rapid accurate diagnosis during surgery is increasing. This study was conducted to develop a tissue method using confocal microscopy after simple staining that does not require freezing slicing. At present, fluorescence with generalized real-time surgery. In this paper, we propose Hoechst 33342 Eosin The proposed can be used as part suitable use operating room, although...
A method for reducing the power consumption of set-associative caches is proposed. The tracks way information all cache blocks and allows access only those ways that potentially contain requested block. When used a 512KB eight-way 64B-block L2 cache, reduces energy by 79%.
A multimodal nonlinear microscope using single source and detector was developed. With the we successfully acquired two-photon excited fluorescence (TPEF), second-harmonic generation (SHG), coherent anti-Stokes Raman scattering (CARS) back reflection images of biological samples.