Increased inflammatory activity is known to be a pathophysiologic characteristic of atrial fibrillation. Familial Mediterranean fever (FMF) disease characterized by recurrent and sustained increased activity. Atrial conduction abnormalities in these patients have not been investigated terms P-wave duration, dispersion (Pd), electromechanical delay measured tissue Doppler echocardiography (TDE). We aimed assess time with FMF.A total 33 FMF (13 males/20 females, 28.4 +/- 12.5 years), controls...

Familial Mediterranean fever (FMF) is a disease characterized by sporadic, paroxysmal attacks of and serosal inflammation. QT dispersion (QTd) transmural repolarization (TDR), simple noninvasive arrhythmogenic markers, that can be used to assess homogeneity cardiac repolarization, have not been studied in FMF patients before. The aim our study was evaluate the QTd TDR without overt involvement. A total 50 with (30 men, 20 women, 29.4 +/- 11.8 years) controls women; mean age 31.3 11.9 were...

Background: The only established therapy for chronic viral delta hepatitis, the most severe form of hepatitis is treatment with pegylated-interferon α (Peg IFN α). Objectives: In this study, we aimed to determine efficacy 2a (Peg-IFN 2a) and 2b 2b) in patients infected virus. Patients Methods: sample size was based on available potentially be recruited. Data 63 receiving either Peg alpha or were retrospectively assessed present cohort study performed Turkey. Of 56 completed 41 received 15 12...

Journal Article QT dispersion and transmural of repolarization in patients with familial Mediterranean fever Get access Ahmet Akcay, Akcay Department Cardiology, Faculty Medicine, Kahramanmaras Sutcuimam University, Kahramanmaras, TurkeyKSU Tıp Fakültesi, Hanefi Oksuz Kardiyoloji Hastanesi, 46050 Turkey Correspondence to: KSU e-mail: dr.akcay@yahoo.com.tr Search for other works by this author on: Oxford Academic Google Scholar Gurkan Acar, Acar Mehmet Sayarlioglu, Sayarlioglu Rheumatology,...

F-Fluorodeoxyglucose (F-FDG) PET/CT represents an imaging modality that is gaining increasingly more prominence in screening, staging, and therapeutic monitoring of malignant diseases. An incidental focus uptake different regions the body not uncommon finding during imaging. Patients with gastrointestinal tract findings comprise ∼3% overall patient group. The aim current study was to provide contributory information relation answer on most appropriate approach cases colonic F-FDG uptake.A...

Pistacia terebinthus is used as a coffee substitute in the East and Southern Anatolia regions of Turkey. It contains unsaturated fatty acids, tocopherols, polyphenols carotenoids. P. has anti-inflammatory potential antioxidant activity. In this study we evaluated protective effects (PTC) on thioacetamide (TAA)-induced liver injury rats.Twenty-eight male Sprague-Dawley rats were equally randomized into four groups. Chronic was induced with TAA (100 mg/kg i.p. three times weekly). The first...

Organ failures that develop due to acute pancreatitis (AP), some laboratory values and the anthropometric characteristics of patients have been shown play a role in prognosis AP increasingly used investigate disease although classification systems, such as Ranson's criteria, are still habitually. In this stud, we aimed relationship organ observed during course AP, biochemical parameters compare using Atlanta Classifica-tion (AC) systems.Laboratory values, data, including waist circumference...

Pegylated-interferon alpha (Peg-IFN α) is the therapy most commonly used to treat chronic hepatitis delta virus (HDV) infection. In present study, we planned investigate effect of IL28B polymorphism on response Peg-IFN α and disease progression in patients with HDV.A total 47 who received Peg-IFNα for at least one year were investigated. The divided into three groups based their treatment: sustained viral (SVR) (32%), unresponsive (53%), relapse (15%). compared terms age, gender, blood...

Azathioprine (AZA) is an immunosuppressive drug that widely used in the treatment of autoimmune diseases. Although AZA widely, many studies reported AZA-related hepatotoxicity rather rare. We aimed to present a case with severe cholestatic hepatitis due use for Behcet's disease. Three weeks after starting uveitis, patient was admitted our clinic cholestasis and constitutional symptoms. In liver biopsy, findings were accordance reaction, stopped. After 2 months, bilirubin levels tests results...

Background Obese non-alcoholic fatty liver disease (NAFLD) was found to increase the risk of developing atrial fibrillation (AF) regardless metabolic syndrome subgroups that may accompany it. In this study, effect NAFLD on structural and electrical functions heart investigated using tissue Doppler echocardiography (TDE) in non-obese patients without any known factors for AF. Material methods The study included 43 female (31.3±3.8 years), who had stage 2–3 hepatosteatosis detected by...

In this study, we aimed to investigate the histological and clinical effect of angiotensin-converting enzyme (ACE) ACE gene polymorphism in nonalcoholic fatty liver disease (NAFLD) their roles progression disease.Liver function tests, body mass index, waist circumference, lipid parameters, fasting blood glucose (FBG), hemoglobin A1c (HbA1c), homeostasis model assessment-IR (HOMA-IR), ACE, were evaluated NAFLD group control group. The study was by dividing into four subgroups (D/D homozygous,...

Background/Aims: Hepatitis C virus (HCV) infection is an important global public health problem.Application of screening programs for elimination HCV in addition to direct-acting antiviral (DAA) therapies.In this study, we aimed measure knowledge, attitudes, and behaviors family physicians (FPs) who are regarding diagnosis, natural history, treatment infection.Materials Methods: This study was designed as a cross-sectional aiming at measuring knowledge levels about screening, FPs working...

Objective Arum dioscoridis is a plant that has been shown to regulate biological activity on oxidation, immune system and inflammation grown in our country. We aimed investigate the effects of arum experimental colitis related acetic acid rats. Material Methods In this study 56 Wistar Albino female rats, 6 weeks old, weighing 180- 210 g, were seperated into 7 equal groups with 8 animals each group. Group 1 control one without any administration. An created 2. 3 treated prophylactic oral...

Aims: Metabolic dysfunction-associated steatotic liver disease (MASLD) remains the most common chronic worldwide. It is considered to be a complication of metabolic syndrome. The main element in intra- and extrahepatic disorders MASLD oxidative/nitrosative stress (ONS). relationship between increase decrease these markers degree steatosis defined sonographically has not been specifically studied before. Methods: Patients spectrum were divided into 3 groups according on ultrasonography (US)....

The aim of this study was to investigate the prophylactic and therapeutic effects Arum dioscoridis (tirsik) plant extract against thioacetamide-induced experimental liver toxicity.In study, 35 male Wistar-Albino rats, 12-14 weeks old, weighing between 200 270 g, were used. Rats divided into 5 groups 7 each. first group determined as control group, second hepatotoxicity third prophylaxis fourth intraperitoneal treatment fifth oral group. Hepatotoxicity achieved with a single dose 350 mg/kg...

In this study, we aimed to elucidate fibrosis in patients who visited our outpatient clinic with complaints such as abdominal pain and dyspepsia had fatty liver by ultrasound imaging.A total of 119 were admitted the gastroenterology institution incidentally detected hepatosteatosis on imaging included study. Patients examined for FibroScan-502-touch (Echosens, Paris, France) elastic tissue ultrasonography device. The effects these parameters possible degree investigated.No was 75 (63.02%)...

Drug-Induced Liver Injury (DILI) may develop depending on the drug itself, its metabolites or host immune system. Hydroxychloroquine (HQC) is used prevalently in treatment of rheumatological diseases (especially SLE), and severe liver toxicities associated with this have been reported literature. We are presenting a 36-year-old patient who was using hydroxychloroquine due to adult Still’s disease (ASD) whose initial values were normal but arrived three weeks later severely high...

Non-steroid anti-inflamatuar ilaçları (NSAID) (Aspirin dahil) kullananlarda risk faktörlerine bağlı olarak; %3- 4.5 klinik gastrointestinal (GİS) sistem olayı, 1/70 semptomatik ülser, 1/5 endoskopik %1.5 (1-4) (major kanama, perforasyon, obstruksiyon vd.) ciddi komplikasyon, 1/150 kanayan 1/1200 ölüm gelişeceği tahmin edilmektedir. ani-inflamatuar ilaçlar gastrik ve düodenal ülserle ilişkili anlamlı derecede morbidite mortaliteye neden olurlar. Gastrointestinal olay gelişiminde NSAID’ların...

Giriş-Amaç Ülseratif kolit, kolonu diffüz tutan mukozal inflamasyonla karakterize rekürren, idiyopatik ve kronik bir hastalıktır. Kolitde, oksidan/antioksidan dengenin bozulduğu gözlenmiştir. N-asetilsistein β-glukan ise antioksidan, anti-inflamatuvar özellikte olan maddeler olup kolitde yararlı etkilerini araştırmayı amaçladık. Materyal-Metod 220-250 gr 50 adet erkek Wistar Albino rat kullanıldı. Grup I (Kontrol):Tek doz rektal saline uygulandı, sonrası 6 gün normal besin verildi. II...

Background and Aim: Although vaccination practices continue at a fast pace around the world, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) still threatens people's lives. In this study, we aimed to determine presence of SARS-CoV-2 in patients who do not have typical symptoms novel disease 2019 (COVID-19), but only present with dyspepsia, investigate role immature granulocytes early diagnosis these patients. Material Methods: Adult pediatric suffering from dyspepsia were...

Objective: Fatty liver (hepatosteatosis) means that fat in the exceeds 5% at least by ownliver weight. Nonalcoholic hepatosteatosis (NAHS) can be seen all age and ethnic groups.The frequency general population is about 14% to 30%. Ultrasonography mostcommonly used method for diagnosis of since it cheap, non-invasive andeasily accessible. The two findings from among diffusely increased echogenicity inproportion spleen kidney, blurred intrahepatic vascular structures reduction inpenetration...

Eosinophilic gastroenteritis (EGE) is a rare disorder and eosinophilic infiltration of the gastrointestinal tract characteristic for it. ascites may seen in lymphoma, gastroenteritis, peritoneal dialysis, parasitic infections too. Depending on dominant layer EGE classified into three types namely, mucosal, muscularis serosal. Rarest type serosal characterized by primary disease, peripheral eosinophilia ascites. Here we report case EGE. We have discussed clinical cornerstones diagnosis...