African swine fever (ASF) is a virulent infectious disease of pigs. As there no effective vaccine and treatment method at present, it poses great threat to the pig industry once breaks out. In this paper, we used ASF outbreak data WorldClim database meteorological selected CfsSubset Evaluator-Best First feature selection combined with random forest algorithms construct an prediction model. Subsequently, also established test set for other than modelling, accuracy value range model on...

To explore the clinical and genetic characteristics of two children diagnosed with rare diseases simultaneously. Two comorbidity due to dual mutations at Third Affiliated Hospital Zhengzhou University respectively in May 2022 March 2023 were selected as study subjects. Clinical data retrospectively analyzed. This has been approved by Ethics Committee (Ethic No. 2021-062-01). Child 1 was a 2-year-and-4-month-old boy whose manifestations included facial dysmorphism, developmental delay, short...

Coronary artery disease (CAD) is the leading cause of death worldwide, and aberrant phagocytosis may be involved in its development. Understanding this aspect provide new avenues for prompt CAD diagnosis. CAD-related information was obtained from Gene Expression Omnibus datasets GSE66360, GSE113079, GSE59421. We identified 995 upregulated 1086 downregulated differentially expressed genes (DEGs) GSE66360. Weighted gene co-expression network analysis revealed a module 503 relevant to CAD....

Foot-and-mouth disease (FMD) is a highly contagious of livestock worldwide, and FMD outbreaks have become serious obstacle for the development animal husbandry. To explore distribution characteristics transmission between 2010 2017 in China, Global Moran's I test Getis-Ord Gi index were used to analysis spatial cluster; Space-time permutation scan statistic was applied spatio-temporal pattern; GIS-based method employed create map representing pattern, directional trend hotspots each...

Peste des Petits Ruminants (PPR) is an acute and highly contagious transboundary disease caused by the PPR virus (PPRV). The infects goats, sheep some wild relatives of small domestic ruminants, such as antelopes. listed World Organization for Animal Health animal that must be reported promptly. In this paper, outbreak data combined with WorldClim database meteorological were used to build a prediction model. Using feature selection methods, eight sets features selected: bio3, bio10, bio15,...

Since the first two novel coronavirus cases appeared in January of 2020, outbreak COVID-19 epidemic seriously threatens public health Italy. In this article, distribution characteristics and spreading various regions Italy were analysed by heat maps. Meanwhile, spatial autocorrelation, spatiotemporal clustering analysis kernel density method also applied to analyse COVID-19. The results showed that Italian has a temporal trend aggregation. was concentrated northern gradually spread other...

Peste des petits ruminants (PPR) is a highly infectious disease that mainly infects small ruminants. To date, PPR has been confirmed in more than 70 countries. In China, occurred 20 provinces and cities. this study, based on geographic information system (GIS), spatial analysis was used to examine the occurrence of China from 2007 2018. The results showed first Tibet gradually spread other provinces. outbreaks were concentrated 2014, 2015 Combining climate factors with maximum entropy...

Lead ions (Pb

Peste des petits ruminants (PPR) is a serious disease that affects goats, sheep and other small ruminants. As one of the earliest most countries, PPR has seriously threatened India's animal husbandry economy.In this study, spatiotemporal characteristics in India outbreaks were analyzed. Between 2010 2018, epidemic broke out all over country cluster distribution. Epidemic clusters northern southern are at higher risk, outbreak time significant seasonality. The results analysis development...

As a highly toxic and refractory heavy metal contaminant, Pb2+ has seriously endangered human health. The problems of low sensitivity high cost signal labeling often exist in common electrochemical biosensor. Herein, biosensor was constructed using DNAzyme-driven bipedal DNA walker catalytic hairpin assembly as the multistage amplification strategy. Compared with Zr-MOF, nanocomposite material gold nanoparticle @ zirconium-based organic framework (AuNPs@Zr-MOF) larger porosity specific...

Background: Nilatinib is an irreversible tyrosine kinase inhibitor, which used in the treatment of some kinds cancer. To study interaction between Neratinib and MAD2L1, a potential tumor target, guiding significance for enriching medicinal value Neratinib. Method: The binding mechanism Mitotic arrest deficient 2-like protein 1 (MAD2L1) under simulative physiological conditions was investigated by molecule simulation multi-spectroscopy approaches. Results: Molecular docking showed most...

Abstract Background Foot-and-mouth disease (FMD) is a highly contagious of livestock worldwide. Russia big agricultural country with wide geographical area where FMD outbreaks have become an obstacle for the development animal and products trade. In this study, we aimed to assess export risk from Russia. Results After simulation by Monte Carlo, results showed that probability cattle infected in surveillance zone (Surrounding areas no epidemic has occurred within prescribed time limit,...

Abstract Background Peste des petits ruminants (PPR) is a serious disease that damages goats, sheep and other small ruminants. As one of the earliest most countries, PPR has seriously threatened India's animal husbandry economy. Results In this study, spatial temporal characteristics outbreak were analyzed. Between 2010 2018, epidemic in India broke out all over country cluster distribution. Herd concentration southern an area with high mortality PPR, time significant seasonality. Then,...

Abstract Bluetongue (BT) causes an economic loss of $3 billion every year in the world. After two serious occurrences BT (bluetongue virus [BTV] occurrence 2006 and 2015), France has been controlling for decades, but it not eradicated. As largest live cattle export market world, is also one major exporters breeding animals genetic materials The biosafety its exported products always a concern. scenario tree quantitative model was used to analyze risk BTV release from French bovine semen....

This study was designed to explore the effect of medical-nurse integration health education in aged patients undergoing percutaneous vertebroplasty. A total 72 with osteoporotic vertebral compression fractures, who obtained vertebroplasty from June 2019 May 2022 were selected this study. Patients divided into control group (n = 36) and experimental according time hospitalization. The received routine education, while education. We evaluated participants on 4 key aspects, their understanding...

Peste des petits ruminants (PPR) is a serious disease that damages goats, sheep and other small ruminants. India, as one of the earliest most countries, PPR has seriously threatened India's animal husbandry economy. In this study, spatial temporal characteristics outbreak were analyzed. The in India was distributed all parts country presented cluster distribution. Herd concentration southern an area with high mortality PPR, time significant seasonality. Then, analysis development...