A5003440679- Coral and Marine Ecosystems Studies
- Marine Sponges and Natural Products
- Force Microscopy Techniques and Applications
- Neuroscience and Neural Engineering
- Plant Virus Research Studies
- Aquaculture disease management and microbiota
- Photosynthetic Processes and Mechanisms
- Conducting polymers and applications
- Immune Cell Function and Interaction
- Aquaculture Nutrition and Growth
- Advanced Fluorescence Microscopy Techniques
- Monoclonal and Polyclonal Antibodies Research
- Lipid Membrane Structure and Behavior
- Bacteriophages and microbial interactions
- CAR-T cell therapy research
University of California, Berkeley
2021-2023
University of Puerto Rico System
2017
Voltage-sensitive fluorescent reporters can reveal fast changes in the membrane potential neurons and cardiomyocytes. However, many cases, illumination presence of results disruptions to action shape that limits length recording sessions. We show here a molecular prosthetic approach, previously limited fluorophores, rather than indicators, be used substantially prolong imaging
A convenient enzymatic strategy is reported for the modification of cell surfaces. Using a tyrosinase enzyme isolated from Agaricus bisporus, unique tyrosine residues introduced at C-termini nanobodies can be site-selectively oxidized to reactive o-quinones. These intermediates undergo rapid with nucleophilic thiol, amine, and imidazole present on surfaces, producing novel nanobody-cell conjugates that display targeted antigen binding. We extend this approach toward synthesis nanobody-NK...
Photosynthetic light harvesting requires efficient energy transfer within dynamic networks of light-harvesting complexes embedded phospholipid membranes. Artificial models are valuable tools for understanding the structural features underpinning absorption and chromophore arrays. Here, a method attaching protein-based model to planar, fluid supported lipid bilayer (SLB) is developed. The protein consists tobacco mosaic viral capsid proteins that gene-doubled create tandem dimer (dTMV)....
Background The roles of gorgonian sclerites as structural components and predator deterrents have been widely studied. Yet their role barriers against microbes has only recently investigated, even less is known about the diversity chemical compounds associated with sclerites. Methods Here, we examine semi-volatile organic compound fraction (SVOCs) from healthy diseased Gorgonia ventalina sea fan corals to understand possible a stress response or in defense infection. We also measured...
Abstract Photosynthetic light harvesting requires efficient energy transfer within dynamic networks of complexes embedded phospholipid membranes. Artificial models are valuable tools for understanding the structural features underpinning absorption and chromophore arrays. Most artificial static or in solution phase, rather than a two-dimensional fluid environment as natural photosynthesis. We have developed method attaching protein-based model to supported lipid bilayer (SLB), which provides...
Voltage-sensitive fluorescent reporters can reveal fast changes in membrane potential neurons and cardiomyocytes. However, many cases, illumination the presence of results disruptions to action shape that limits length recording sessions. We show here a molecular prosthetic approach, previously limited fluorophores, rather than indicators, be used substantially prolong imaging
Voltage-sensitive fluorescent reporters can reveal fast changes in membrane potential neurons and cardiomyocytes. However, many cases, illumination the presence of results disruptions to action shape that limits length recording sessions. We show here a molecular prosthetic approach, previously limited fluorophores, rather than indicators, be used substantially prolong imaging