A5039401980- Hemostasis and retained surgical items
- Surgical Sutures and Adhesives
- Polymer Surface Interaction Studies
- Hydrogels: synthesis, properties, applications
- Platelet Disorders and Treatments
- Blood properties and coagulation
- Plant Virus Research Studies
- Hemophilia Treatment and Research
- Supramolecular Self-Assembly in Materials
- Advanced Drug Delivery Systems
- biodegradable polymer synthesis and properties
- Studies on Chitinases and Chitosanases
- Periodontal Regeneration and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Animal Disease Management and Epidemiology
- Gastrointestinal Bleeding Diagnosis and Treatment
Korea Advanced Institute of Science and Technology
2015-2021
Adhesives play an important role in industrial fields such as electronics, architectures, energy plantation, and others. However, adhesives used for medical purpose are rather under‐developed compared with those industry consumer products. One key property required is to maintain their adhesiveness the presence of body fluid. Here, entirely new class called TAPE reported; this produced by intermolecular hydrogen bonding between a well‐known polyphenol compound, tannic acid, poly(ethylene...
For the increasing demand of soft materials with wide ranges applications, hydrogels have been developed exhibiting variety functions (e.g., stretchable, self-healing, stimuli-responsive, and etc.). So far, add-in components such as inorganic nanoparticles, carbon materials, clays, many others to main polymers used achieve various unique hydrogels. The multicomponent hydrogel systems often exhibit batch-dependent inconsistent results problems in mixings, require labors during preparations,...
Mussel-inspired adhesion chemistry provides a useful alternative to the use of fibrin glues.
This video describes the simplest protocol for preparing biodegradable surgical glue that has an effective hemostatic ability and greater water-resistant adhesion strength than commercial tissue adhesives. Medical adhesives have attracted great attention as potential alternative tools to sutures staples due their convenience in usage with minimal invasiveness. Although there are several protocols developing including those commercially available such fibrin glues cyanoacrylate-based...
This video describes the simplest protocol for preparing biodegradable surgical glue that has an effective hemostatic ability and greater water-resistant adhesion strength than commercial tissue adhesives. Medical adhesives have attracted great attention as potential alternative tools to sutures staples due their convenience in usage with minimal invasiveness. Although there are several protocols developing including those commercially available such fibrin glues cyanoacrylate-based...
Marine mussels secrete adhesive proteins to attach solid surfaces. These contain phenolic and basic amino acids exhibiting wet adhesion properties. This study used a mussel-inspired hemostatic polymer, chitosan-catechol, treat gastrointestinal bleeding caused by endoscopic mucosal resection in heparinized porcine model. We aimed evaluate the efficacy short-term safety of this chitosan-catechol. 15 pigs. Four iatrogenic ulcers classified as Forrest Ib were created each pig using an method....
Since the discovery of polyphenolic underwater adhesion in marine mussels, researchers strive to emulate this natural phenomenon development adhesive hemostatic materials. In study, bio-inspired materials that lead pseudo-active blood coagulation, utilizing traditionally passive polymer matrices chitosan and gelatin are developed. The two-layer configuration, consisting a thin, blood-clotting catechol-conjugated (CHI-C) layer thick, barrier-functioning (Geln) ad-layer, maximizes capability...