A5055692191- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Cardiac and Coronary Surgery Techniques
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Aortic aneurysm repair treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Congenital Heart Disease Studies
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Cardiomyopathy and Myosin Studies
- Pericarditis and Cardiac Tamponade
- Lung Cancer Diagnosis and Treatment
- Tissue Engineering and Regenerative Medicine
- Cardiac Arrhythmias and Treatments
- Cardiac Ischemia and Reperfusion
- Coronary Artery Anomalies
- Congenital heart defects research
- Ultrasound in Clinical Applications
- Pleural and Pulmonary Diseases
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrest and Resuscitation
King Saud Medical City
2020-2024
Creative Commons
2023
Politecnico di Milano
2014-2022
Alessandro Manzoni Hospital
2012-2020
Aziende Socio Sanitarie Territoriali di Lecco
2018
University of Milan
2017
NorthEast Regional Epilepsy Group
2016
Research Network (United States)
2016
Harefield Hospital
2007-2010
Fondazione Poliambulanza Istituto Ospedaliero
2003-2006
It is generally believed that increase in adult contractile cardiac mass can be accomplished only by hypertrophy of existing myocytes. Documentation myocardial regeneration acute stress has challenged this dogma and led to the proposition myocyte renewal fundamental homeostasis. Here we report human aortic stenosis, increased results from a combination hyperplasia. Intense new formation differentiation stem-like cells committed lineage. These express stem cell markers telomerase. Their...
Background— Prosthesis-patient mismatch (PPM) occurs when the effective orifice area (EOA) of prosthesis being implanted is too small in relation to body size, thus causing abnormally high transvalvular pressure gradients. The objective this study was examine midterm impact PPM on overall mortality and cardiac events after aortic valve replacement patients with pure stenosis. Methods Results— indexed EOA (EOAi) estimated for each type size 315 consecutive defined as an EOAi ≤0.80 cm 2 /m...
Abstract Comprehensive information on the characteristics of surgical heart valves (SHVs) is essential for optimal valve selection. Such also important in assessing SHV function after replacement. Despite existing regulatory framework sizing and labelling, this challenging to obtain a uniform manner various SHVs. To ensure that clinicians are adequately informed, European Association Cardio-Thoracic Surgery (EACTS), The Society Thoracic Surgeons (STS) American (AATS) set up Task Force...
Small-sized aortic bioprostheses may cause high postoperative gradients. In clinical practice, it is difficult to compare from different manufactures, owing the discrepancy between true size and nominal of prosthesis inter-patient variability in root characteristics. vitro studies provide accurate data, using a system which possible implant should enable fair comparison be made. The present study compared four most widely used pericardial stented manufacturers surgically implanted small...
To identify the effects of time between myocardial infarction and surgery, site infarction, mitral involvement on ventricular geometry, clinical outcome in treatment ischemic cardiomyopathy patients with heart failure.Sixty-nine consecutive cardiomyopathy, indexed end-systolic volume > or =50 mL/m(2), ejection fraction < =35%, failure underwent surgery 81.9 +/- 100.8 months after using different techniques restoration. Thirteen geometric parameters were studied pre- postoperatively. Paired...
The Trifecta aortic bioprosthesis (St. Jude Medical, Inc., St. Paul, MN, USA) is a stented pericardial heart valve with excellent preliminary results. Aim of the study was to evaluate its early clinical and hemodynamic performances in multicenter regional registry.Between January 2011 June 2012, 178 consecutive patients undergoing replacement were prospectively enrolled at 9 Italian centers. Clinical echocardiographic data collectedat discharge, 6-months 1-year postoperatively.The average...
Background Patients with a small aortic annulus, that is ≤23 mm, constitute challenge for the surgeon, because they are at high risk of patient-prosthesis mismatch. Stentless valves provide better hemodynamic performance rest and during exercise than stented valves, advocated in this group patients. A new-generation valve, Trifecta (St. Jude), has recently become available improved hemodynamics. The aim study was to compare Freestyle (Medtronic) patients annulus. Methods From September 2012...
Background Stentless valves have long been considered the ideal in terms of hemodynamics. Recently, Trifecta valve, a stented bioprosthesis with excellent fluid dynamic characteristics, has become available. The aim study was to compare opening/closing pattern Freestyle stentless valve and that native aortic valve. Methods A total 12 patients 10 were compared normal control patients. Leaflet kinematics hemodynamic parameters obtained by echocardiographic M-mode Doppler measurements. Results...
Several novel approaches were recently developed to treat aortic root pathologies. The alteration induced by some of these the biomechanics could possibly affect coronary perfusion, compromising procedural outcome. In this scenario, need replicate in vitro flow pattern physiological and pathological conditions is becoming crucial for functional assessment devices techniques. This article describes design an easy-to-use, left-and-right impedance simulator, coupled with native roots pulsatile...