A5053971929- Thyroid Disorders and Treatments
- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Pregnancy and Medication Impact
- Liver Disease Diagnosis and Treatment
- Telemedicine and Telehealth Implementation
- Neonatal and fetal brain pathology
- Thyroid Cancer Diagnosis and Treatment
- Air Quality and Health Impacts
- Medical and Health Sciences Research
- Genetic Associations and Epidemiology
- Adipose Tissue and Metabolism
- Neonatal Health and Biochemistry
- Human Health and Disease
- Surgical site infection prevention
- Ethics and Legal Issues in Pediatric Healthcare
- Cardiac, Anesthesia and Surgical Outcomes
- Sleep and related disorders
- Advanced Neuroimaging Techniques and Applications
- Adipokines, Inflammation, and Metabolic Diseases
- Mental Health Treatment and Access
- Cancer Risks and Factors
- Colorectal Cancer Surgical Treatments
- Pesticide Exposure and Toxicity
- Neuroscience of respiration and sleep
Erasmus MC
2013-2024
Erasmus University Rotterdam
2019
Erasmus MC - Sophia Children’s Hospital
2019
Centers for Disease Control and Prevention
2011
<h3>Importance</h3> Air pollutants interact with estrogen nuclear receptors, but their effect on thyroid signaling is less clear. Thyroid function of particular importance for pregnant women because the thyroid's role in fetal brain development. <h3>Objective</h3> To determine short-term association exposure to air pollution first trimester throughout pregnancy. <h3>Design, Setting, and Participants</h3> In this cohort study, 9931 from 4 European cohorts (the Amsterdam Born Children Their...
Animal studies suggest that organophosphate (OP) pesticides exposure affects thyroid function, but evidence in humans remains sparse and inconclusive. Gestational is of particular interest, since hormone essential for fetal brain development. OP are able to cross the placental blood-brain barrier may interfere with development processes regulated by hormone. To investigate association gestational during pregnancy maternal cord blood concentrations. This study was embedded within Generation R...
Background Sleep problems occur in up to 30% of children and have been associated with adverse developmental outcomes. However, due a lack longitudinal neuroimaging studies, the neurobiological changes that may underlie some these associations remained unclear. This study explored association between sleep during childhood white matter ( WM ) microstructure preadolescence. Methods Children from population‐based birth cohort, Generation R Study, who had repeatedly assessed 1.5 10 years age...
Background: Severe maternal iodine deficiency during pregnancy leads to marked intellectual disability in the offspring. Although recent studies showed that even mild-to-moderate is associated with lower intelligence quotient and attention deficit hyperactivity disorder offspring, underlying neurobiological mechanism of these associations remains unknown. The aim this study was investigate association excretion offspring brain morphology pre-adolescence. Methods: This embedded within...
Abstract Background Low maternal urinary iodine concentration (UIC) during pregnancy is associated with adverse offspring neurodevelopment. Thyroglobulin (Tg) has been suggested as a more sensitive biomarker than UIC of long-term status, but associations Tg neurodevelopment and the possible mediating role thyroid function remain unknown. Aim To study whether i) newborn ii) IQ brain morphology. Methods Participants were selected from two population-based prospective cohorts: Generation R (the...
More and more, medical practitioners use modern technologies such as apps wearables in their treatment plan. The GDPR defines these kinds of data 'data concerning health'. However, also the term 'medical data' is being used. Furthermore, Council Europe uses terms 'personal health welfare data'. Using all different makes it difficult to understand what protected by not. This article gives an historical overview evolution protection health, which leads a discussion on current broad definition...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Genome-wide association studies in adults have identified 42 loci associated with thyroid stimulating hormone (TSH) and 21 free thyroxine (FT4) concentrations. While biologically plausible, age-dependent effects not been assessed. We aimed to study the of previously genetic determinants TSH FT4 concentrations newborns (pre)school children.
Background Expedited partner therapy (EPT) is the practice of providing treatment without a clinical assessment to sex partners patients with diagnosed STD. EPT legal for Chlamydia trachomatis (CT) infections in New York State. To guide implementation at City STD (NYC STD) clinics, we estimated potential use and treatments dispense. Methods We analysed electronic medical record data heterosexual patient visits NYC clinics 2009. estimate use, measured: proportion clinic presumptive diagnosis...