A5021929665- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Blood donation and transfusion practices
- COVID-19 Impact on Reproduction
- Liver Disease and Transplantation
- Drug-Induced Hepatotoxicity and Protection
- Blood transfusion and management
- Organ Donation and Transplantation
- Peripheral Neuropathies and Disorders
- Liver Disease Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and Mental Health
- Blood groups and transfusion
- Tumors and Oncological Cases
- Retinal and Optic Conditions
- Hepatitis B Virus Studies
- Hair Growth and Disorders
- Pharmacological Effects and Toxicity Studies
- Multiple Sclerosis Research Studies
- Neuroscience of respiration and sleep
- Psychosomatic Disorders and Their Treatments
- Genetic and rare skin diseases.
- Thermal Regulation in Medicine
- Liver Diseases and Immunity
- Diabetes Management and Research
Institute of Liver and Biliary Sciences
2020-2024
All India Institute of Medical Sciences Bhopal
2019-2021
All India Institute of Medical Sciences
2019
All India Institute of Medical Sciences Raipur
2019
Post Graduate Institute of Medical Education and Research
2018
People’s University
2014-2016
Yale University
2007
New York University
2007
Abstract Background The role of convalescent plasma (COPLA) for the treatment severely ill Corona Virus Disease-2019 is under investigation. We compared efficacy and safety with fresh frozen (FFP) in severe COVID-19 patients. Methods findings This was an open-label, single-centre phase II RCT on 29 patients from India. One group received COPLA standard medical care (SMC) (n=14), another FFP SMC (n=15). A total were randomized two groups. Eleven out 14 (78.5%) remained free ventilation at day...
This study aimed to evaluate the safety and efficacy of therapeutic plasma exchange (TPE) in pediatric acute liver failure (PALF).
Importance No proven treatment is available for severely ill COVID-19. Therapeutic use of COVID-19 convalescent plasma (COPLA) under investigation. Objective To compare the efficacy COPLA with standard medical therapy (SMT) alone in severe patients. Design, setting and participants A multicentric, open-labelled, phase-III randomised controlled trial conducted at two centres collected third dedicated centre North-India, coordinating during from June 2020 to December 2020. The study population...
Abstract Background Therapeutic Plasma Exchange (TPE) and Intravenous Immunoglobulin both are first‐line treatments for Guillain Barre Syndrome; however, there is a significant difference in cost. We undertook this study to assess the cost minimization treating Syndrome patients. Methods A prospective randomized controlled trial was undertaken, which 40 (GBS) patients with GBS disability score of grade four five were enrolled. societal perspective adopted analysis assessment health system...
Intense monocyte activation and infiltration into the target tissues are main mechanisms of lung injury in severe acute respiratory syndrome coronavirus 2 infection. A reduction degree nature such cellular responses is expected following recovery. We aimed to investigate immune moderate disease 2019 (COVID-19) patients recovered patients.Moderate COVID-19 (n = 34) at Lok Nayak Hospital, New Delhi, 15) from mild who were considered for convalescent plasma (COPLA) donation Institute Liver...
Currently the treatment of choice for critical liver failure is transplantation. Liver treated conservatively until a matching donor becomes available. The therapeutic plasma exchange (TPE) plays an important role as bridge to transplantation by removing accumulated toxins from patient plasma, well restoring coagulation profile. This was retrospective study on critically ill disease patients who underwent TPE January 2012 September 2015. data were collected analyses parameters, function...
background: Role of Convalescent plasma (COPLA) to treat severe COVID-19 is under investigation. We compared efficacy and safety COPLA with fresh frozen (FFP) in patients. Methods: One group received standard medical care (n = 14), another random donor FFP, as control 15) disease. Results: The proportion patients free ventilation at day seven were 78.5% group, 93.3 % not significant (p= 0.258). However, improved respiratory rate, O2 saturation, SOFA score, Ct value observed the group. No...
Liver transplant is a life-saving treatment, but due to the limited availability of suitable liver donors, ABO-incompatible transplants (ABOi-LT) are conducted increase donors. Perioperative desensitization for ABOi-LT an established strategy circumvent risk graft rejection. A single prolonged session can be performed achieve desired titers avoid using multiple immunoadsorption (IA) columns or off-label reuse single-use columns. This study retrospectively assessed effectiveness...
Abstract Primary sclerosing cholangitis (PSC) is rarely associated with autoimmune hemolytic anemia (AIHA), and the presence of specific autoantibodies has not been reported previously. We present a unique case report PSC AIHA implicating autoanti-C. A 17-year-old girl was admitted to our hospital along AIHA. Her blood sample demonstrated positive direct antiglobulin test autocontrol in antihuman globulin phase, confirming patient had warm-reactive Further testing showed possibility anti-C....
ABSTRACT Intense monocyte activation and infiltration into the target tissues is main mechanism of lung injury in SARS CoV2 infection. A reduction degree nature such cellular responses expected following recovery. We aimed to investigate immune severe Covid-19 patients recovered patients. Methods Severe COVID-19 (n=34) at Lok Nayak Hospital, New Delhi (n=15) from mild disease considered for convalescent plasma (COPLA) donation Institute Liver Biliary Sciences (ILBS), were recruited....
India has almost 3,000 blood centres collecting more than 11 million units annually. Maintaining supply during the COVID-19 pandemic is a huge challenge. We conducted cross-sectional study by an online survey to analyse variation of practices across centers this pandemic. A total 196 completely responded survey. Most who were part Government hospitals (60 %), academic institutes (55.6 %) and directly supporting COVID hospital (67.5 %). Almost 95.4 % reported reduction donation mainly due...
To investigate the approach of both pharmacies and herbalists' shops while offering a proper advice for patients seeking guidance on potentially malignant oral lesion.A cross-sectional, descriptive study was undertaken using standardized patient representative sample in Bhopal city. The selected by stratified random sampling technique contacted telephone. Our patient's introductory statement was, "I have painful ulceration tongue since 3 months. What would you advise?" avoid hypothetical...
Background: Due to the stringent criteria for selection of blood donors, donor deferral rate is increasing day by day, leading a decrease in base bank. This study was done analyze incidence and pattern review recruitment retention policy highlight role nutrition improvement.Methods: A retrospective observational single-centre conducted department transfusion medicine North-East region India from April 2018 2019.Results: During period, total 3920 donations were made, 1992 donors deferred. The...
Understanding the attitude and motives differences between voluntary replacement blood donation is key to sustainable availability of this precious resource. This study aimed assess for convalescent plasma (CP) in recovered COVID-19 donors further understand donation.This prospective cross-sectional survey-based was conducted among500 who visited CP at a tertiary care super-speciality centre northern India. Data were collected using structured questionnaire based on donor attitude, motives,...
Introduction: In quality management system for process improvement and better inventory management, a performance monitoring tool is critical in the blood bank to improve discard rate of component one essential elements.This study was designed analyse their reason newly developed institute setup. Material Methods: It retrospective observational from May 2018 March 2019.During period data captured analysed preparation discarded individually cumulatively.Major reasons were discard.Results:...
Neuromyelitis Optica (NMO) is a demyelinating inflammatory disorder of the spinal cord and optic nerve. As per American Society For Apheresis (ASFA) guidelines, Therapeutic Plasma Exchange (TPE) considered as second-line treatment in patients with weak or no response to steroid therapy. A patient NMO presented tertiary care institute sudden loss vision right eye. The was resistant improved significantly TPE. Hence, TPE may be an effective modality steroid-resistant loss.
The escalating need for blood component due to increasing accidents and surgeries are always challenging banks hospitals. In this fast busy world, collecting from a healthy voluntary donor is quite time constraints. Many donors who wish donate were unable go the bank because of simultaneous operational timings office hours donors. We dealt with concern by extending donation also started on weekends following LAARC (Listen, Acknowledge, Assess, Respond, Confirm) methodology as pilot project...