A5031544307- Stroke Rehabilitation and Recovery
- Cerebral Palsy and Movement Disorders
- Botulinum Toxin and Related Neurological Disorders
- Acute Ischemic Stroke Management
- Balance, Gait, and Falls Prevention
- Muscle activation and electromyography studies
- Musculoskeletal pain and rehabilitation
- Nutrition and Health in Aging
- EEG and Brain-Computer Interfaces
- Parkinson's Disease Mechanisms and Treatments
- Body Composition Measurement Techniques
- Medical Imaging and Analysis
- Telemedicine and Telehealth Implementation
- Ophthalmology and Eye Disorders
- Transcranial Magnetic Stimulation Studies
- Diabetic Foot Ulcer Assessment and Management
- Motor Control and Adaptation
- Prosthetics and Rehabilitation Robotics
- Effects of Vibration on Health
- Neuroscience and Neural Engineering
- Occupational Health and Performance
- Myofascial pain diagnosis and treatment
- COVID-19 and Mental Health
- Spinal Cord Injury Research
- Multiple Sclerosis Research Studies
Don Carlo Gnocchi Foundation
2016-2025
International Flame Research Foundation
2020-2025
University of Pavia
2024
iRobot (United States)
2019
Università Cattolica del Sacro Cuore
2018-2019
Scuola Superiore Sant'Anna
2019
Sapienza University of Rome
2011-2015
Bambino Gesù Children's Hospital
2012-2014
After stroke, only 12% of survivors obtain complete upper limb (UL) functional recovery, while in 30% to 60% UL deficits persist. Despite the complexity UL, prior robot-mediated therapy research has used one robot comparisons conventional therapy. We evaluated efficacy robotic treatment using a set 4 devices, compared with therapy.In multicenter, randomized controlled trial, 247 subjects subacute stroke were assigned either (using devices) or treatment, each consisting 30 sessions. Subjects...
Abstract Background The majority of stroke survivors experiences significant hand impairments, as weakness and spasticity, with a severe impact on the activity daily living. To objectively evaluate deficits, quantitative measures are needed. aim this study is to assess reliability, validity discriminant ability instrumental provided by robotic device for rehabilitation, in sample patients subacute stroke. Material methods In study, 120 40 controls were enrolled. Clinical evaluation included...
Nowadays, objective measures are largely used to evaluate spasticity for overcoming the intrinsic limitations of clinical scales. Among measures, Tonic Stretch Reflex Threshold (TSRT) seems most promising. Previous studies demonstrated validity and reliability TSRT in assessment at elbow ankle level adults. The purposes this study were assess: (i) feasibility joint children with Cerebral Palsy (CP), (ii) correlation between scores. A mechatronic device, pediAnklebot, was impose 50 passive...
In the last few years, there has been an increasing interest in use of robotic devices to objectively quantify motor performance patients after brain damage. Although these robot-derived measures can potentially add meaningful information about patient's dexterity, as well be used outcome measurements rehabilitation treatment, they need validated before being clinical practice. The present work aims evaluate reliability, validity and discriminant ability metrics provided by a novel device...
Robotic rehabilitation of the upper limb has demonstrated promising results in terms improvement arm function post-stroke patients. The current literature suggests that robot-assisted therapy (RAT) is comparable to traditional approaches when clinical scales are used as outcome measures. Instead, effects RAT on capacity execute a daily life task with affected unknown, measured using kinematic indices. Through analysis drinking task, we examined performance between patients following robotic...
Context Chronic Neurological Disorders (CNDs) are among the leading causes of disability worldwide, and their contribution to overall need for rehabilitation is increasing. Therefore, identification new digital solutions ensure early continuous care mandatory. Objective This protocol proposes test usability, acceptability, safety, efficacy Telerehabilitation (TR) protocols with robotic tools in reducing perceived level CNDs including Parkinson's Disease (PD), Multiple Sclerosis (MS),...
Bioelectrical Impedance Vector Analysis (BIVA) is a valuable tool for evaluating hydration and body composition, but its application in subacute post-stroke patients remains unexplored. This study aimed to fill this gap by analyzing BIVA cohort of 87 (42 women, mean age 69 ± 12) undergoing rehabilitation. At admission (T0), diagnosis malnutrition with GLIM criteria sarcopenia EWGSOP2 was done, were analyzed BIVA. The change modified Barthel Index (mBIT1-mBIT0) assessed evaluate the...
Friedreich’s ataxia (FRDA) is the most common hereditary autosomal recessive form of ataxia. In this disease there early manifestation gait ataxia, and dysmetria arms legs which causes impairment in daily activities that require fine manual dexterity. To date no cure for disease. Some novel therapeutic approaches are ongoing different steps clinical trial. Development sensitive outcome measures crucial to prove effectiveness. The aim study was assess reliability sensitivity quantitative...
Monitoring gait quality in daily activities through wearable sensors has the potential to improve medical assessment Parkinson's Disease (PD). In this study, four partitioning methods, two based on thresholds and a machine learning approach, considering four-phase model, were compared. The methods tested 26 PD patients, both OFF ON levodopa conditions, 11 healthy subjects, during walking tasks. All subjects equipped with inertial placed feet. Force resistive used assess reference time...
Background: After a stroke, up to three-quarters of acute and subacute stroke survivors exhibit cognitive impairment, with significant impact on functional recovery, quality life, social engagement. Robotic therapy has shown its effectiveness motor recovery but not fully investigated. Objective: This study aims assess the technological rehabilitation intervention functions in patients using set three robots one sensor-based device for upper limb rehabilitation. Methods: is pilot which...
After a stroke, patients can suffer from sarcopenia, which affect recovery. This could be closely related to an impairment in nutritional status. In this preliminary analysis of longitudinal prospective study, we screened 110 subjects admitted our rehabilitation center after stroke. We then enrolled 61 patients, who underwent 6-week course treatment. identified group 18 sarcopenic (SG), according the European Working Group on Sarcopenia Older People 2 (EWGSOP2), by evaluating muscle strength...
Robot-mediated therapy is a viable approach for upper limb rehabilitation. The highly complex segment and the identification of appropriate devices capable rehabilitating it globally (from shoulder to hand) in clinical practice crucial. In this work, we aimed: (i) describe an used identifying set technological robotic treat limb, (ii) evaluate feasibility identified practice. Using ad-hoc form, multidisciplinary team four sensor-based limb. Then, 30 stroke patients were enrolled assigned two...
After a cerebral stroke insult, there is an overproduction of Reactive Oxygen Species (ROS), which overcome the antioxidant defenses, causing further tissues damage. The status oxidative stress in patients over time, particularly those undergoing rehabilitation treatments, has been poorly investigated. We analyzed 61 subacute (33 females and 28 males) admitted to our center by measuring, serum: hydroperoxides levels (d-ROMs), activity (BAP test), relative capacity (OSI index). also for...
The available clinical outcome measures of disability in multiple sclerosis are not adequately responsive or sensitive.To investigate the feasibility inertial sensor-based gait analysis sclerosis.A cross-sectional study 80 patients and 50 healthy controls was performed. Lower-limb kinematics evaluated by using a commercially magnetic measurement unit system. Mean standard deviation range motion (mROM, sROM) for each joint lower limbs were calculated one minute walking test. A motor...
The estimation of the body’s center mass (CoM) trajectory is typically obtained using force platforms, or optoelectronic systems (OS), bounding assessment inside a laboratory setting. use magneto-inertial measurement units (MIMUs) allows for more ecological evaluations, and previous studies proposed methods based on either single sensor sensors’ network. In this study, we compared accuracy two MIMUs. Body CoM was estimated during six postural tasks performed by 15 healthy subjects, data...
Recently, the use of robotic technology in gait and balance rehabilitation stroke patients has been introduced, with positive results. The purpose this study was to evaluate effectiveness trunk compared training alone on balance, activities, participation measures subacute stroke. a randomized, controlled, single blind, parallel group clinical trial. Thirty-six first ischemic or hemorrhagic event were enrolled, they randomized two groups: Gait Group (GG), where received only treatment for...