A5066925575- Ovarian cancer diagnosis and treatment
- Cancer Mechanisms and Therapy
- Endometrial and Cervical Cancer Treatments
- PARP inhibition in cancer therapy
- Uterine Myomas and Treatments
- Regulation of Appetite and Obesity
- Social and Behavioral Studies
- Chemokine receptors and signaling
- Surgical Sutures and Adhesives
- Cancer Cells and Metastasis
- Vitamin C and Antioxidants Research
- Immune cells in cancer
- Vitamin D Research Studies
- Drug Transport and Resistance Mechanisms
- Cell death mechanisms and regulation
- Nanoparticles: synthesis and applications
- Renal and related cancers
- Mechanisms of cancer metastasis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Sarcoma Diagnosis and Treatment
- T-cell and Retrovirus Studies
- Advances in Oncology and Radiotherapy
- Trace Elements in Health
- Wheat and Barley Genetics and Pathology
- Pelvic floor disorders treatments
Poznan University of Medical Sciences
2009-2025
University Hospital of Lord’s Transfiguration
2015-2017
Background: High-grade advanced ovarian, fallopian tube, and primary peritoneal (HGAOC) cancers require both surgical systemic treatment. The introduction of polyADP-ribose polymerase inhibitors (PARPis) has significantly improved outcomes. This study presents an analysis HGAOC patients treated at a single center, following updated guidelines. Methods: We observed 437 women newly diagnosed with the Department Gynecological Oncology between January 2018 December 2023. Results: Since November...
Vaults are cytoplasmic ribonucleoprotein particles composed of three proteins (MVP, TEP1, vPARP) and vault‑associated RNAs (vRNAs). Although the cellular functions vaults remain unclear, strongly linked to development multidrug resistance (MDR), major obstacle efficient treatment cancers. Available published data suggest that their components frequently upregulated in broad variety multidrug-resistant cancer cell lines tumors different histological origin. Here, we provide detailed analysis...
PAX8 gene encodes one of the transcription factors engaged in regulation proper development thyroid gland as well Müllerian and renal/upper urinary tracts. So far, six alternatively spliced transcripts were reported, however, sequences only four deposited NCBI database. Here, we evaluate a fragment novel variant mRNA formed by an alternative 3' acceptor site located second exon. The molecular outcome encompasses extension 5' untranslated region exon two 97 nucleotides is evident from mRNA....
Chemokine stromal cell‑derived factor‑1 (SDF‑1) and its receptors, CXCR4 CXCR7, have been implicated in epithelial ovarian cancer progression metastasis. However, limited data are available on the expression levels of SDF‑1 variants CXCR7 human cancer. The present study aimed to characterize pattern SDF‑1, normal ovaries transcript was determined by quantitative polymerase chain reaction (qPCR). Plasma SDF‑1α were commercially EIA kits antigen 125 (CA 125) quantified automated microparticle...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Markowska A, Lubin J, Jaszczyńska-Nowinka K, Pawałowska M, Mądry R. The influence of viral, bacterial and parasitic infections on the development neoplasia. Contemporary Oncology/Współczesna Onkologia. 2011;15(1):7-14. doi:10.5114/wo.2011.20525. APA Markowska, A., Lubin, J., Jaszczyńska-Nowinka, K., Pawałowska, M., & Mądry, (2011). Onkologia, 15(1), 7-14. https://doi.org/10.5114/wo.2011.20525 Chicago Anna,...
High-grade advanced ovarian, fallopian tube and primary peritoneal (HGAOC) cancer are malignancies in which, apart from surgical treatment, systemic treatment plays an important role. The improvement results is associated with the introduction of polyADP-ribose polymerase inhibitors (PARPis). aim this study to present a cross-section patients treated for HGAOC, one center, including distribution principles following most up-to-date guidelines. We observed who reported Department...
High-grade advanced ovarian, fallopian tube and primary peritoneal (HGAOC) cancer are malignancies in which, apart from surgical treatment, systemic treatment plays an important role. The improvement results is associated with the introduction of polyADP-ribose polymerase inhibitors (PARPis). aim this study to present a cross-section patients treated for HGAOC, one center, including distribution principles following most up-to-date guidelines. We observed who reported Department...
Angiogenesis is crucial for the development and progression of malignant neoplasms. In terms molecular mechanisms leading to development...
Witamina D oraz witaminy C, E i A, należące do antyoksydantów, wykazują aktywność przeciwnowotworową
e13017 Background: Cerebral metastases develop in 10-30% of patients with breast cancer and around 3.3 to 4% ovarian cancer. The present study evaluates the expression ER alpha beta receptors, PR, HER2 markers associated metastases: stromal cell-derived factor-1 (SDF1) its receptor CXCR4, metastasis suppressor (BRMS1), astrocyte elevated gene (AEG-1), depending on status BRCA1 protein cancerous cells (somatic mutation). Methods: material originated from 30 women 22 whom cerebral were...
A case report of a 50-cm diameter and 20-kg mass benign ovarian tumor. Total abdominal hysterectomy with bilateral salpingooophorectomy was performed full patient recovery. Fibrothecomas can remain long asymptomatic grow to giant sizes.