A5040581094- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Polymer Surface Interaction Studies
- Advanced Drug Delivery Systems
- Hydrogels: synthesis, properties, applications
- HIV/AIDS drug development and treatment
Tehran University of Medical Sciences
2015-2024
Academic Center for Education, Culture and Research
2015
Shariati Hospital
2015
Many of the treatment regimens available for hepatitis C include sofosbuvir. Unfortunately, sofosbuvir has not been recommended use in patients with severe renal impairment leaving these group very few options. Nevertheless, there are many reports which have treated sofosbuvir-containing regiments without important adverse events. This study aims at determining safety and effectiveness a sofosbuvir-based impairment, including those on hemodialysis.We enrolled subjects estimated glomerular...
Abstract The present study deals with preparation and optimization of a novel chitosan hydrogel‐based matrix by suspension cross‐linking method for controlled release Depo‐Medrol. Depo‐Medrol effective Rheumatoid arthritis disease has become an imperative field in the drug delivery system. In this context, it was intended to optimize loading circumstances experimental design also kinetics entrapped order obtain maximal efficiency loading. optimum concentrations (2.5 g), glutaraldehyde (3.05...
Sofosbuvir (SOF) is a revolutionary treatment for patients with hepatitis C virus (HCV). However, its efficacy and safety among end-stage renal disease (ESRD) remains controversial. In this study, we examined the levels of SOF metabolite (GS-331007) (SOF-007) in human plasma infected HCV having ESRD using an optimized liquid chromatography-mass spectrometry (LC-MS) analytical method.