A5000056347- Antimicrobial Peptides and Activities
- Agriculture and Biological Studies
- Mycotoxins in Agriculture and Food
- Scientific Research and Studies
- Biochemical and Structural Characterization
- Protein Hydrolysis and Bioactive Peptides
- Milk Quality and Mastitis in Dairy Cows
- Insect and Pesticide Research
- Toxin Mechanisms and Immunotoxins
- Probiotics and Fermented Foods
- Veterinary medicine and infectious diseases
- Animal Nutrition and Physiology
- Food Industry and Aquatic Biology
- Immune Response and Inflammation
- Microbial infections and disease research
- Animal Nutrition and Health
- Gut microbiota and health
- Animal Virus Infections Studies
- Transgenic Plants and Applications
- Viral Infectious Diseases and Gene Expression in Insects
- Animal Diversity and Health Studies
- Legal, Health, Environmental and COVID-19 Challenges
- NF-κB Signaling Pathways
- Environmental and Biological Research in Conflict Zones
- Virus-based gene therapy research
Sumy National Agrarian University
2016-2024
Henan Institute of Science and Technology
2022
Mastitis is an inflammatory disease caused by microbial infection. Chlorogenic acid (CGA), one of the major phenolic acids in Taraxacum officinale , has natural antioxidant and anti-inflammatory properties various cell types; however, effects CGA on Lipoteichoic (LTA)-induced bovine mammary epithelial cells (BMECs) have not been investigated. In this study, content T . was determined High-performance liquid chromatography (HPLC). BMECs were infected with LTA to induce mastitis model....
Staphylococcus aureus is a common pathogen that can cause pneumonia and variety of skin diseases. Skin injuries have high risk colonization by S. aureus, which increases morbidity mortality. Due to the emergence multidrug-resistant strains, antimicrobial peptides are considered be among best alternatives antibiotics due their unique mechanism action other characteristics. MPX an antibacterial peptide extracted from wasp venom has activity against bacteria. This study revealed good...
Simultaneous aflatoxin (AFB1) and zearalenone (ZEN) contamination in agro-products have become widespread globally a toxic superposition effect. In the present study, we describe highly sensitive specific dual lateral flow immunochromatographic assay (dual test strip) for rapid simultaneous detection of AFB1 ZEN food feed samples based on respective monoclonal antibodies (mAbs). Two immunogens AFB1-BSA (an bovine serum albumin (BSA) conjugate) ZEN-BSA (a BSA were synthesized oximation active...
Escherichia coli can cause intestinal diseases in humans and livestock, destroy the barrier, exacerbate systemic inflammation, seriously threaten human health animal husbandry development. The aim of this study was to investigate whether antimicrobial peptide mastoparan X (MPX) effective against E. infection. BALB/c mice infected with by intraperitoneal injection, which represents a sepsis model. In study, MPX exhibited no toxicity IPEC-J2 cells notably suppressed levels interleukin-6...
Zearalenone (ZEN) contamination in food and feed is prevalent has severe effects on humans animals post-consumption. Therefore, a sensitive, specific, rapid, reliable method for detecting single residue of ZEN necessary. This study aimed to establish highly sensitive specific monoclonal antibody (mAb) an indirect competitive enzyme-linked immunosorbent assay (icELISA) the detection residues feed. The immunogen ZEN-BSA was synthesized via amino glutaraldehyde (AGA) diazotization (AD) methods...
This study aimed to detect and monitor total Zearalenone (ZEN) its five homologs (ZENs) in cereals feed. The monoclonal antibodies (mAbs) with a high affinity broad class specificity against ZENs were prepared, the conditions of heterologous indirect competitive ELISA (icELISA) preliminarily optimized based on ZEN mAbs. immunogen ZEN-BSA was synthesized using oxime active ester method (OAE) identified infrared (IR) ultraviolet (UV). coating antigen ZEN-OVA obtained via 1,4-butanediol...
Restrictions on antibiotics are driving the search for alternative feed additives to promote gastrointestinal health and development in broiler chicken production. Proteins including antimicrobial peptides can potentially be applied as alternatives one of most promising alternatives. We investigated whether addition MPX diet affects production performance, immune function intestinal flora caecal contents chickens. One hundred one-day-old chickens were randomly divided into two groups:...
Objective: Abrus precatorius is a universal panacea in herbal medicine. In view of this, phytochemical screening, proximate analysis, median lethal dose (LD50), hematological and biochemical effects extracts A. seed was studied Mus musculus. Materials methods: Nineteen (19) mice were used for the study. Four (4) determination aqueous ethyl acetate respectively. The LD50 aquous estimated at 187.5±62.5 mg/Kg 175±75 remaining fifteen (15) divided into 3 groups 5 each studies. Group 1...
Objectives: The aim of the research is histological study corrective effect compound potassium 2((4-amino-5-(morpholinomethyl)-4H-1,2,4-triazol-3yl)thio)acetate (PKR-173) with different antibiotics on state chicken's liver under infection by Pseudomonas aeruginosa. Materials and Methods: was carried out levers intact chickens (intact control); that were infected strain aeruginosa (controlled pathology); had (before being aeruginosa) preventive input PKR-173 classic antibiotic Enrofloxacin or...
The aim of research was to analyze the contents somatic cells (SC) in goat milk East Ukraine, level SC translocation process milking, speed evacuation their secret, conduct monitoring and ranging on herds Eastern region during 2015 seasonally. Somatic cell count studied a large number animals different zones Ukraine (1800 samples). appears up 800×10³ cells/ml at 65-71% samples by method laser-running cytometry with account only those having DNA nucleus. While subpopulations it is shown that...
Background. This study aimed to explore the zearalenone (ZEN) immunogen synthesis method, immunogenicity, and antibody characteristics lay a foundation for establishment of immunoassay methods ZEN single residue its analogs total residue. Methods. Based on molecular structure active sites ZEN, oxime ester (OAE), condensation mixed anhydride (CMA), formaldehyde (FA), 1,4-butanediol diglycidyl ether method (BDE) were designed used (ZEN-BSA) synthesis. The immunogens identified by infrared (IR)...
The results of the effect feeding chelated form Zinc on safety, productivity and slaughter parameters broiler chickens are presented.
 aim this study was to determine broilers background Zinc.
 Materials methods. Experimental studies were conducted during 2020 cross Cobb-500 in vivarium Veterinary Faculty Sumy National Agrarian University (Ukraine), divided into two groups principle analogues (control experimental) 50 each. source zinc for control group their sulfates. Chelated...
Animal rights in recent years occupy a significant place among the themes of general national discourse Ukraine. This year, under pressure public Ukraine, law according to humane attitude towards "younger brothers" was adopted. But which do animals have? And what’s really going on? Legislation on animal protection is not executed even at level where it is. How often people who cause suffering my country have appropriate punishment? The report provides an analysis preconditions for reforming...
СВОЙСТВА ШТАММОВ СAMPYLOBACTER
An epizootiology of infectious diseases/conditions dog in some veterinary clinics from Benue, Plateau states and the Federal Capital Territory Nigeria were assessed 2015 to 2018. This study revealed about seventeen (17) clinical cases/conditions 1865 cases recorded within period four (4) years. These comprised helminthoses (17.8%) having highest prevalence followed by babesiosis (17.5%), parvovirosis (15.9%), ectoparasitism (11.3%), scepticemia (6.9%), Mange (5.7%), urinary tract infections...
An important element in ensuring the epizootic well-being of poultry industry is disinfection. Modern farming requires a large number effective disinfectants. It known that resistance microorganisms to effects disinfectants based on genotypic mechanism. The nature formation and antiseptics different than antibiotics. With regard disinfectants, formed more slowly proportion resistant strains population may not be high for long time. This due mechanisms antibiotics first case – plasmid...
The purpose of the work was to study antimicrobial activity 2-((4-R-3-(morfolinomethylene)-4H-1,2,4-triazole-5-yl)thio) acetic acid salts by "hanging drop" and "serial dilution" methods in broth (limiting concentration option) establish some patterns "structure – action" depending.Materials methods. objects research were 9 new compounds salts. These are crystal substances which odorless, soluble water organic solvents. To achieve a more objective picture we applied two methods: option)....
Інтенсивне вирощування свиней призводить до погіршення санітарно-гігієнічних умов утримання. Крім того, виробничі стреси сприяють зниженню резистентності організму тварин. Прорив імунітету відображається на збільшенні випадків інфекційних захворювань серед молодняку. Для запобігання невиправданого використання антибіотиків та покращення імунної відповіді у поросят були проведені випробування пробіотичних штамів Bacillus subtilis господарстві з розведення «Інституту сільського господарства...
The object of this study is the force parameters working process when cleaning udder nipples cows from contamination. Failure to provide adequate care for a cow, especially concerning its udder, could lead significant health and productivity problems. On other hand, utilizing modern tools, devices, materials improve sanitary hygienic conditions milking care, thus leading better overall outcomes. As part research, mathematical expressions were derived theoretically, allowing determination...