Aixiang Ding

ORCID: 0000-0002-0770-7098
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Research Areas
  • Luminescence and Fluorescent Materials
  • Molecular Sensors and Ion Detection
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Advanced biosensing and bioanalysis techniques
  • 3D Printing in Biomedical Research
  • RNA Interference and Gene Delivery
  • Crystallography and molecular interactions
  • Photochromic and Fluorescence Chemistry
  • Nanoplatforms for cancer theranostics
  • Organic Light-Emitting Diodes Research
  • Advanced Materials and Mechanics
  • Lipid metabolism and biosynthesis
  • Advanced Photocatalysis Techniques
  • Sulfur Compounds in Biology
  • Adenosine and Purinergic Signaling
  • Electrocatalysts for Energy Conversion
  • Virus-based gene therapy research
  • Cellular Mechanics and Interactions
  • TiO2 Photocatalysis and Solar Cells
  • Receptor Mechanisms and Signaling
  • Supramolecular Self-Assembly in Materials
  • Advancements in Battery Materials
  • Electrospun Nanofibers in Biomedical Applications
  • Supercapacitor Materials and Fabrication

University of Illinois Chicago
2020-2025

Xiamen University
2022-2025

Xinyang Normal University
2017-2022

Case Western Reserve University
2019-2021

Beijing Normal University
2016-2018

Anhui University
2013-2015

Hefei University
2014

4D bioprinting is promising to build cell-laden constructs (bioconstructs) with complex geometries and functions for tissue/organ regeneration applications. The development of hydrogel-based bioinks, especially those allowing living cell printing, easy preparation, defined composition, controlled physical properties critically important bioprinting. Here, a single-component jammed micro-flake hydrogel (MFH) system heterogeneous size distribution, which differs from the conventional granular...

10.1002/adma.202109394 article EN Advanced Materials 2022-01-22

Formation of graded biomaterials to render shape-morphing scaffolds for 4D biofabrication holds great promise in fabrication complex structures and the recapitulation critical dynamics tissue/organ regeneration. Here we describe a facile generation an adjustable robust gradient using single- or multi-material one-step strategy biofabrication. By simply photocrosslinking mixed solution photocrosslinkable polymer macromer, photoinitiator (PI), UV absorber live cells, cell-laden hydrogel with...

10.1016/j.bioactmat.2021.05.021 article EN cc-by-nc-nd Bioactive Materials 2021-06-05

Developing and healing tissues begin as a cellular condensation. Spatiotemporal changes in tissue geometry, transformations the spatial distribution of cells extracellular matrix, are essential for its evolution into functional tissue. 4D materials, 3D materials capable geometric changes, may have potential to recreate aforementioned biological phenomenon. However, most reported non-degradable and/or not biocompatible, which limits their application regenerative medicine, date there no...

10.1002/adfm.202010104 article EN Advanced Functional Materials 2021-02-24

Construction of multifunctional nonviral gene vectors to execute defined tasks holds great potential for the precise and effective treatment gene-associated diseases. Herein, we have developed four large π-conjugation triphenylamine derivatives bearing two polar [12]aneN3 heads a lipophilic tail applications in delivery, one/two-photon-triggered near-infrared (NIR) fluorescence bioimaging, combined photodynamic therapy (PDT) cancer. These compounds possess typical NIR aggregation-induced...

10.1021/acsami.1c02600 article EN ACS Applied Materials & Interfaces 2021-05-13

Abstract Shape‐morphing hydrogels bear promising prospects as soft actuators and for robotics. However, they are mostly restricted to applications in the abiotic domain due harsh physicochemical conditions typically necessary induce shape morphing. Here, multilayer hydrogel actuator systems developed using biocompatible photocrosslinkable oxidized, methacrylated alginate gelatin that permit encapsulation maintenance of living cells within implement programmed controlled actuations with...

10.1002/advs.202004616 article EN cc-by Advanced Science 2021-03-01

Two α-cyanostilbene derivatives exhibiting bright emission in both well-dissolved solutions ( Φ > 49%) and the solid state 95%) have been synthesized as novel DSEgens for high-contrast mechanofluorochromism (>50 nm) live cell imaging.

10.1039/d2qo01192a article EN Organic Chemistry Frontiers 2022-01-01

4D bioprinting techniques that facilitate formation of shape-changing scaffold-free cell condensates with prescribed geometries have yet been demonstrated. Here, a simple approach is presented enables shape-morphing condensate-laden bilayer system. The strategy produces which morph over time into predefined complex shapes. Cell bilayers specific are readily fabricated by technologies. tunable deformability and microgel (MG) degradation, enabling controllable morphological transformations...

10.1002/smll.202202196 article EN Small 2022-08-16

Dual-state emission luminogens (DSEgens) are receiving research interest in the construction of multifunctional materials due to their inherent advantage high efficiency both molecularly dispersed solution state and solid state. However, it remains challenging synthesizing DSEgens via a delicate manipulation molecular structures. This work presents an example bright DSEgen synthesis by tuning electronic structures conformations. Three coumarin-tetraphenylethylene (TPE) molecules with...

10.1002/chem.202203628 article EN Chemistry - A European Journal 2023-01-14

Abstract Amine‐functionalized α‐cyanostilbene derivatives ( Z )‐2‐(4‐aminophenyl)‐3‐(4‐butoxyphenyl)acrylonitrile (ABA) and )‐3‐(4‐butoxyphenyl)‐2‐[4‐(butylamino)phenyl]acrylonitrile (BBA) were designed for specific recognition of picric acid (PA), an environmental biological pollutant. The 1:1 host–guest complexes formed between the chemosensors PA enhanced fluorescence quenching, thus leading to sensitive selective detection in aqueous media solid phase.

10.1002/chem.201402790 article EN Chemistry - A European Journal 2014-07-31

A highly efficient and stable electrocatalyst with the novel heterostructure of Co-embedded N-doped carbon nanotubes supported Mo2C nanoparticles (Mo2C/NCNTs@Co) is creatively constructed by adopting one-step metal catalyzed carbonization-nitridation strategy. Systematic characterizations density functional theory (DFT) calculations reveal advanced structural electronic properties Mo2C/NCNTs@Co heterostructure, in which CNTs tunable diameters present electron-donating effect work function...

10.1021/acsami.9b14316 article EN ACS Applied Materials & Interfaces 2019-10-21

Luminogens with distinct photophysical properties were synthesized by attaching TPE and TPA on a saturated cyclohexyl ring in an isolated fashion, demonstrating the effectiveness of concept “aryl isolation” engineering AIEgens DSEgens.

10.1039/d2tc00350c article EN Journal of Materials Chemistry C 2022-01-01

The fusion of multiple rigid, planar units into a highly twisting molecule is proposed as molecular engineering strategy for synthesizing bright dual-state emitters. Applications such mechanosensor and fluorescent probe have been demonstrated.

10.1039/d2qm00067a article EN Materials Chemistry Frontiers 2022-01-01

Lipid droplet (LD) dysfunction can result in various diseases, such as nonalcoholic fatty liver disease. Imaging agents built on dual-state emission (DSE) molecules that fluoresce both dilute solutions and the aggregated state are receiving attention this type of probe could provide bright fluorescence signals at variable concentrations, avoiding false signal readout caused by concentration fluctuation living systems. Herein, we identified a red emissive molecule featuring DSE, from three...

10.1002/asia.202201291 article EN Chemistry - An Asian Journal 2023-02-15

A novel α-cyanostilbenic derivative, (Z)-2-(4-aminophenyl)-3-(4-(dodecyloxy)phenyl) acrylonitrile, is reported, wherein a Z–E isomerization process accompanied by remarkable decrease in compatibility with liquid crystals. Accordingly, fluorescent-molecule-dispersed crystals have been prepared through photoisomerization-induced phase separation method. The photoluminescence can be repeatedly switched an electric field. Modulating the excitation light offers new technique to explore...

10.1039/c3tc32174f article EN Journal of Materials Chemistry C 2013-12-13

A new strategy has been innovatively proposed for wrapping the Ni-incorporated and N-doped carbon nanotube arrays (Ni-NCNTs) on porous Si with robust Ni–Si interfacial bonding to form core–shell-structured NCNTs-Ni2Si@Si. The hierarchical silicon core was first fabricated via a novel self-templating synthesis route based two crucial strategies: in situ thermal evaporation of crystal water from perlite producing SiO2 subsequent magnesiothermic reduction into Si. Ni-NCNTs were subsequently...

10.1021/acs.langmuir.9b00558 article EN Langmuir 2019-04-22
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