A5033939036- Luminescence and Fluorescent Materials
- RNA Interference and Gene Delivery
- Molecular Sensors and Ion Detection
- Advanced biosensing and bioanalysis techniques
- Supramolecular Self-Assembly in Materials
- Dendrimers and Hyperbranched Polymers
- Nitric Oxide and Endothelin Effects
- Porphyrin and Phthalocyanine Chemistry
- Photochromic and Fluorescence Chemistry
- Analytical Chemistry and Sensors
- Lipid Membrane Structure and Behavior
- Sulfur Compounds in Biology
- Virus-based gene therapy research
- Supramolecular Chemistry and Complexes
Beijing Normal University
2017-2018
As part of an effort to develop generally applicable strategies for creating probes suitable detecting important molecular and ionic species, the oxidative aromatization nonfluorescent 9,10-dihydroacridine derivatives triggered by peroxynitrite (ONOO–) led identification compound 2H, 9-phenyl-9,10-dihydroacridine-4-carboxylic acid, as a rapid-responding fluorescent probe capable ONOO– with extraordinary selectivity. Adding little more than 1 equiv solution 2H resulted in over 100-fold...
Four gemini amphiphiles decorated with triazole-[12]aneN3 as the hydrophilic moiety and various long hydrocarbons hydrophobic moieties, 1-4, were designed to form micelles possessing aggregation-induced emission (AIE) property for gene delivery tracing. All four give ultralow critical micelle concentrations, are pH-/photostable biocompatible, completely retard migration of plasmid DNAs at low concentrations. The DNA-binding abilities fully assessed. coaggregated nanoparticles 1-4 could...
A NO-response amphiphile was successfully formed into vesicles in aqueous solution, which could encapsulate and control the release of carboxyfluorescein (CF) as a model drug <italic>in vitro</italic> living cells.
Among six oligoamides, <bold>G1–G6</bold>, <bold>G2</bold> stands out as a versatile gelator to form stable hydrogels well several organogels. The hydrogel of is able encapsulate and release medicinally important substances with acid-responsiveness.