A5044922332- Mosquito-borne diseases and control
- Insect Pest Control Strategies
- Insect symbiosis and bacterial influences
- Traditional and Medicinal Uses of Annonaceae
- Insect and Pesticide Research
- Essential Oils and Antimicrobial Activity
- Trypanosoma species research and implications
- Parasite Biology and Host Interactions
- Insect Utilization and Effects
- Insect-Plant Interactions and Control
- Malaria Research and Control
- Insect Pheromone Research and Control
- Vibrio bacteria research studies
- Phytochemical compounds biological activities
- Papaya Research and Applications
- Hepatitis Viruses Studies and Epidemiology
- Animal Disease Management and Epidemiology
- Natural product bioactivities and synthesis
- Alkaloids: synthesis and pharmacology
- Insect and Arachnid Ecology and Behavior
- Forensic Entomology and Diptera Studies
- Bee Products Chemical Analysis
- Insect Resistance and Genetics
- Parasites and Host Interactions
- Research on Leishmaniasis Studies
Kenya Medical Research Institute
2024
Masinde Muliro University of Science and Technology
2009-2023
International Centre of Insect Physiology and Ecology
2004-2021
Kenyatta University
2004-2021
Field studies were done of the responses Glossina palpalis in Côte d'Ivoire, and G. p. gambiensis tachinoides Burkina Faso, to odours from humans, cattle pigs. Responses measured either by baiting (1.) biconical traps or (2.) electrocuting black targets with natural host odours. The catch was significantly enhanced (∼5×) odour but not humans. In contrast, catches electric showed inconsistent results. For both human increased (>2×) trap targets. palpalis, pigs humans numbers tsetse attracted...
The antiplasmodial, anti-trypanosomal and anti-leishmanial activity of 25 plant extracts obtained from seven Tanzanian medicinal plants: Annickia (Enantia) kummeriae (Annonaceae), Artemisia annua (Asteraceae), Pseudospondias microcarpa (Anacardiaceae), Drypetes natalensis (Euphorbiaceae), Acridocarpus chloropterus (Malpighiaceae), Maytenus senegalensis (Celastraceae) Neurautanenia mitis (Papilonaceae), were evaluated in vitro against Plasmodium falciparum K1, Trypanosoma brucei rhodesiense...
We are attempting to develop cost-effective control methods for the important vector of sleeping sickness, Glossina fuscipes spp. Responses tsetse flies (in Kenya) and G. f. quanzensis Democratic Republic Congo) natural host odours reported. Arrangements electric nets were used assess effect cattle-, human- pig-odour on (1) numbers attracted odour source (2) proportion that landed a black target (1×1 m). In addition responses monitor lizard (Varanus niloticus) assessed in Kenya. The effects...
Effective remedies for disrupting An. gambiae metamorphosis at the egg stage are crucial in suppression of malaria vector populations that result reduction disease burden. 2‐Hydroxy‐4‐methoxybenzaldehyde (the major component Mondia whytei roots), its derivatives, structural analogues and their blends were evaluated against eggs search ovicidal compounds with potential use mosquito control programs. Mature roots harvested from (Hook) Skeels ( Asclepiadaceous ) plants grown Center African...
Malaria, trypanosomiasis and leishmaniasis have an overwhelming impact in the poorest countries world due to their prevalence, virulence drug resistance ability. Currently, there is inadequate armory of drugs for treatment malaria, leishmaniasis. This underscores continuing need discovery development new anti-protozoal drugs. Consequently, urgent research aimed at effective safe anti-plasmodial, anti-trypanosomal anti-leishmanial Bioassay-guided chromatographic fractionation was employed...
Background Several human-produced volatiles have been reported to mediate the host-seeking process under laboratory conditions, yet no effective lure or repellent has developed for field application. Previously, we found a gradation of attractiveness foot odors different malaria free individuals Anopheles gambiae sensu stricto Giles. In this study, odor individual with most attractive ‘smelly’ feet An . was collected, analyzed and blend components identified. Methods The trapped on Porapak Q...
Odor from preferred/non-preferred tsetse fly vertebrate hosts have been exploited in R&D of attractants/repellents the for human and livestock protection. Odors
Since Anopheles mosquitoes which transmit and maintain the malaria parasite breed in outdoor environment, there is an urgent need to manage these mosquito breeding sites. In order elaborate more on ecological landscape of sites, bacterial community structure their interactions with physicochemical factors larval habitats was characterised Kwale County (Kenya), where endemic.The physical characteristics water parameters were determined recorded. Water samples also collected from identified...
One of the serious problems world is facing today antimicrobial resistance on available antibiotics by most bacterial pathogens and rising cost finding effective agents. In recent years, efforts to find new drugs especially from natural sources have been boosted demand for an cure infectious diseases. Only antibacterial activity apis mellifera honey not stingless bee western Kenya has reported. This study was therefore carried out determine effect Plebenia hylderbrandii Meliponula bocandei...
<title>Abstract</title> <bold>Background</bold>: Globally in 2021, there were an estimated 247 million malaria cases 85 malaria-endemic countries which accounted for over 619,000 deaths worldwide. An 27 and 12,600 attributed to Kenya the year 2020 (1). In every 1000 live births, 84 die before attaining 5 years Kenya(12). Despite implementation of several prevention measures, infection is still high with children under age being most vulnerable. As a complimentary existing measured, vaccine...
Abstract Background Effective remedies for disrupting Anopheles gambiae metamorphosis at the egg stage are crucial in suppression of malaria vector populations that result reduction disease burden. 2-Hydroxy-4-methoxybenzaldehyde (the major component Mondia whytei roots), its derivatives, structural analogues and their blends were evaluated against eggs An. search ovicidal compounds with potential use mosquito control programs. Methods Mature roots harvested from plants grown Center African...
Background Anopheles mosquitoes are the main malaria vector and as cases decline in Sub Saharan Africa, there is a growing realisation that new interventions need to be added complement existing control strategies. To date, most effective way prevent malaria. Since parasite maintained by which oviposit, feed rest outdoor environment, an urgent focus on of oviposition sites seeking vectors. In this regard, detailed understanding their larval ecology necessary. study, bacterial community...
Abstract Background Since Anopheles mosquitoes which transmit and maintain the malaria parasite breed in outdoor environment, there is an urgent need to manage these mosquito breeding sites. In order elaborate more on ecological landscape of sites, bacterial community structure their interactions with physicochemical factors larval habitats was characterised Kwale County (Kenya), where endemic. Materials methods The physical characteristics water parameters were determined recorded. Water...
Abstract Background Since Anopheles mosquitoes which transmit and maintain the malaria parasite breed in outdoor environment, there is an urgent need to manage these mosquito breeding sites. In order elaborate more on ecological landscape of sites, bacterial community structure their interactions with physicochemical factors larval habitats was characterised Kwale County (Kenya), where endemic. Materials methods The physical characteristics water parameters were determined recorded. Water...