A5085673348- Robotic Path Planning Algorithms
- Robotics and Sensor-Based Localization
- Parallel Computing and Optimization Techniques
- Formal Methods in Verification
- Impact of Light on Environment and Health
- Embedded Systems Design Techniques
- Distributed Control Multi-Agent Systems
- Neurogenetic and Muscular Disorders Research
- Control and Dynamics of Mobile Robots
- Laser Material Processing Techniques
- Building Energy and Comfort Optimization
- Guidance and Control Systems
- RNA modifications and cancer
- Surface Roughness and Optical Measurements
- Cardiomyopathy and Myosin Studies
- Architecture, Design, and Social History
- Advanced Optical Imaging Technologies
- Logic, programming, and type systems
- Muscle Physiology and Disorders
- Web visibility and informetrics
- Robotics and Automated Systems
- Vehicle emissions and performance
- Semantic Web and Ontologies
- 3D Shape Modeling and Analysis
- Advanced Database Systems and Queries
University Children’s Hospital Basel
2018-2025
University of Basel
2018-2025
Paderborn University
2001-2023
University Hospital of Basel
2018
NXP (Netherlands)
1972-1975
Philips (United States)
1975
Philips (Netherlands)
1972-1973
Philips (Germany)
1970
Abstract Background With the approval of disease-modifying treatments for 5q-spinal muscular atrophy (SMA), there is an increasing need biomarkers disease course and therapeutic response monitoring. Radially sampled Averaged Magnetization Inversion Recovery Acquisitions (rAMIRA) MR-imaging enables spinal cord (SC) gray matter (GM) delineation quantification in vivo. This study aims to assess SC GM patients with 5q-SMA its associations clinical disability. Methods Twenty-one twenty-one age-...
Abstract Risdiplam is a once-daily oral, survival of motor neuron 2 ( SMN2 ) splicing modifier approved for the treatment spinal muscular atrophy (SMA). JEWELFISH (NCT03032172) investigated safety, tolerability, pharmacokinetics (PK), and PK/pharmacodynamic (PD) relationship risdiplam in non-treatment-naïve patients with SMA. enrolled adult pediatric N = 174) confirmed diagnosis 5q-autosomal recessive SMA who had previously received nusinersen n 76), onasemnogene abeparvovec 14), olesoxime...
In this paper, we present an efficient exploration algorithm for architecture/compiler co-designs of application-specific instruction-set processors. The huge design space is spanned by processor architecture parameters as well different compiler optimization strategies. objective multi-dimensional including conflicting objectives such hardware cost, execution time and code size. goal the presented to determine set Pareto-optimal designs settings a given benchmark program.In case study,...
This paper addresses a new obstacle avoidance technique for mobile robots moving in dense and complex environments. Our approach is to integrate two concepts: The Closest Gap (CG) fetching analyzing openings surrounding the robot Tangential Escape (TE) reactive navigation. combination results faster less oscillatory trajectories than well known approaches designed scenarios, e.g. Nearness-Diagram Navigation methods. Motion commands are derived with proven stability Lyapunov sense control...
In this paper a new real-time collision avoidance approach for mobile robots moving in dense and cluttered environments is presented. Our method to adapt the Closest Gap (CG) Navigation technique, which we have proposed an earlier work [1], generate safer smoother robot trajectories. This achieved by introducing additional step analyzing structure of obstacles surrounding robot, generating instantaneous subgoals drive towards collision-free area. The performance as compared with CG...
The basis and development of the glare system now adopted in several European countries are described. From original Söllner curves, which gave a means for evaluating interior lighting installations, limiting can be applied more readily practice has been developed. procedure estimating rating value an installation comparing it with limits is given. method intended use working interiors only.
Article Free Access Share on A joined architecture/compiler design environment for ASIPs Authors: Jűrgen Teich University of Paderborn, Warburger Str. 100, 33098 Germany GermanyView Profile , Ralph Weper Dirk Fischer View Stefan Trinkert Authors Info & Claims CASES '00: Proceedings the 2000 international conference Compilers, architecture, and synthesis embedded systemsNovember Pages 26–33https://doi.org/10.1145/354880.354885Online:01 November 2000Publication History...
In the design of application-specific instruction set processors (ASIPs) a tight interplay between architecture and compiler is utmost importance. Here, we try to characterize space both frontend (intermediate code optimization) backend (architecture-specific generation) that used in order do Architecture/Compiler Co-Exploration for search optimal architecture/compiler combinations. The described results present state development such framework called BUILDABONG [3].
Progress in Europe the design of integrated lighting and air-conditioning systems is reviewed with particular reference to office installations. After establishing that an illumination level range 1000-2000 lux preferred for working areas, glare limitation method Söllner (adopted Germany, Holland Austria), experimental work determine modelling effects, calorimetric measurements studies air movements room spaces are described. Preferred grouped three categories descriptions given typical
With the term Architecture/Compiler Co-exploration, we denote problem of simultaneously optimizing an application-specific instruction set processor (ASIP) architecture as well its generated compiler. In this paper, characterize design space both compiler frontend (intermediate code optimization) and backend (changes machine model) present workflow our framework BUILDABONG. The project consists four phases: (a) entry composition, (b) automatic simulator generation, (c) generation (in...
This paper addresses a new obstacle avoidance method for mobile robots moving in dense and complex environments. Our approach, named Smooth Closest Gap (SCG) Navigation, builds on the concept of (CG) as strategy to detect free openings surrounding robot select most promising one drive through. Obstacle is performed based configuration obstacles between current location selected gap, where all points are considered compute maneuver simultaneously towards gap. Moreover, area available along...
In both interior and public lighting, the ultimate aim of lighting design is to create a luminance pattern in visual field that meets requirements performance, comfort, economy. Roadway can be based on for roadway surface since road occupies main part field. last 20 years, European countries have attempted solve problems way suitable practical application. This period research appears ending. Meanwhile, method as described this paper, becoming increasingly popular countries.
In view of the developing cooperation between European countries in almost every field, question arises whether it is not also now time to commence international preparation common recommendations for interior lighting. order stimulate further discussion, a comparison has been made current lighting Great Britain, France and Germany, taking into account International Guide on Interior Lighting under by CIE. Suggestions are as how various quality aspects should be handled which parameters...
Progressive and irreversible muscle atrophy characterizes Spinal Muscular Atrophy (SMA) other similar disorder diseases. Objective assessment of functions is an essential important, although challenging, prerequisite for successful clinical trials. Current rating scales restrain the movement abnormalities to certain predefined coarse-grained individual items. The Kinect 3-D sensor has emerged as a low-cost portable motion sensing technology used capture track people's in many medical...
Marking of documents by means a laser beam is secure and efficient personalization method. The marking based on carbonization process, which caused focused beam. process gray scale today's standard ID e.g. driver's licenses, passports. - Now it possible to personalize these with colored lettering, company logos or images in photo quality, using new method: CYMart. This development offers the possibility more flexible layout arrangement increased information content. In addition, CYMart...
Our new true-color laser personalization system (CYMart<sup>TM</sup>) for ID cards and documents does not suffer from the disadvantage of producing only black white images as it is known state art systems, which use Nd-YAG lasers. These well-established black-and-white marking systems are valued so highly because created inside material. Therefore, protected counterfeiting tampering. In exactly same manner CYMart<sup>TM</sup> features an embedded image. based on a three-wavelength system,...