A5004083749- Spondyloarthritis Studies and Treatments
- Bone and Joint Diseases
- Psoriasis: Treatment and Pathogenesis
- Autoimmune and Inflammatory Disorders Research
- Hip disorders and treatments
- Functional Brain Connectivity Studies
- Musculoskeletal pain and rehabilitation
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Optical Imaging and Spectroscopy Techniques
- Inflammasome and immune disorders
- Rheumatoid Arthritis Research and Therapies
- Gout, Hyperuricemia, Uric Acid
Third Affiliated Hospital of Sun Yat-sen University
2021-2025
Sun Yat-sen University
2021-2025
Lower back pain comprises the majority of disease burden patients with ankylosing spondylitis (AS), while alterations large-scale brain networks could be implicated in neuropathophysiology pain. The frontoparietal network (FPN) is known as a modulation hub, key nodes dorsolateral prefrontal cortex (dlPFC) and ventrolateral (vlPFC) participating reappraisal process. In this study, we adopted analytical approaches independent component analysis (ICA) seed-based correlation (SCA) to examine...
Background T1-weighted spoiled 3D Gradient Recalled Echo pulse sequences, exemplified by Liver Acquisition with Volume Acceleration-flexible MRI (LAVA-Flex), are currently the preferred MR sequence for detecting erosions of sacroiliac joint (SIJ). However, zero echo time (ZTE) is recently reported to provide excellent visualization cortical bone. Purpose To directly compare diagnostic accuracy ZTE and LAVA-Flex in detection structural lesions SIJ, including erosions, sclerosis space changes....
To study the diagnostic performance of chemical shift-encoded MRI (CSE-MRI) in diagnosis axial spondyloarthritis (axSpA).CSE-MRI images were acquired for consecutive patients complaining back pain as well healthy volunteers. Proton density fat fraction (PDFF) values measured independently by two readers. Diagnostic CSE-MRI was analyzed sensitivity analysis and ROC curve analysis. Logistic regression employed to investigate risk factors extensive deposition SIJs.A total 52 r-axSpA patients,...
This study aimed to investigate the accuracy of identifying enthesitis along with other inflammatory lesions and structural on MRI sacroiliac joints (SIJ) by readers varying experience how training sessions workshops could help improve accuracy.
Fibromyalgia (FM) and ankylosing spondylitis (AS) are both rheumatic diseases characterized by significant musculoskeletal pain. In this study, we investigated the differences of resting-state network (RSN) connectivity gray matter volume (GMV) between FM, AS healthy controls (HCs). We recruited 38 FM patients, 82 patients 61 HCs in study. All participants underwent functional MRI (rs-fMRI) scans a GE 3.0T MR system. Independent component analysis (ICA) was conducted on rs-fMRI data, group...
In this study, we aimed to investigate whether there was a pattern of distribution acute and chronic lesions in the sacroiliac joints (SIJ) patients with axial spondyloarthritis (axSpA).A total 96 diagnosed as axSpA were retrospectively included study. The Spondyloarthritis Research Consortium Canada joint inflammation score (SIS) structural (SSS) used evaluate SIJs. Scores representing bone marrow edema, fatty erosions extracted respectively. By dividing SIJs into sacral or iliac sections,...
Findings of fatty lesions in the context other imaging manifestations, especially bone marrow edema and erosions can effectively assist diagnosis axSpA. Chemical shift-encoded MRI is a sequence which allows for quantification fat signal has been applied evaluation SIJ The objective this study was to investigate diagnostic performance morphological features visualized by CSE-MRI axSpA.Fatty with (subchondral, homogeneity distinct border) were assessed recorded as binary variable each quadrant...