- Cardiovascular Syncope and Autonomic Disorders
- Heart Rate Variability and Autonomic Control
- Botulinum Toxin and Related Neurological Disorders
- Parkinson's Disease Mechanisms and Treatments
- Genetic Neurodegenerative Diseases
- Neurological disorders and treatments
- Mitochondrial Function and Pathology
- Pain Management and Treatment
- Cardiac Arrest and Resuscitation
- Cardiovascular Health and Disease Prevention
- solar cell performance optimization
- Posttraumatic Stress Disorder Research
- Ocular Diseases and Behçet’s Syndrome
- Inflammatory Myopathies and Dermatomyositis
- Photovoltaic System Optimization Techniques
- Migraine and Headache Studies
- Autoimmune Neurological Disorders and Treatments
- Silicon and Solar Cell Technologies
- Nail Diseases and Treatments
- Cerebral Venous Sinus Thrombosis
- Air Quality and Health Impacts
- Nerve Injury and Rehabilitation
- Hereditary Neurological Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Urticaria and Related Conditions
Uniformed Services University of the Health Sciences
2018-2025
Walter Reed National Military Medical Center
2014-2025
Naval Medical Center Portsmouth
2016-2018
University of Minnesota
2015
New York University
2015
Stanford University
2015
National Institute of Neurological Disorders and Stroke
2014
National Institutes of Health
2014
Vigo County Public Library
2013
University of Utah
2009
Postural orthostatic tachycardia syndrome (POTS) is a chronic and often disabling disorder characterized by intolerance with excessive heart rate increase without hypotension during upright posture. Patients experience constellation of other typical symptoms including fatigue, exercise gastrointestinal distress. A patient POTS female child-bearing age, who first displays in adolescence. The onset may be precipitated immunological stressors such as viral infection. variety pathophysiologies...
The National Institutes of Health hosted a workshop in 2019 to build consensus around the current state understanding pathophysiology postural orthostatic tachycardia syndrome (POTS) and identify knowledge gaps that must be addressed enhance clinical care POTS patients through research. This second (of two) articles summarizes gaps, outlines research priorities for POTS.POTS is complex, multi-system, chronic disorder autonomic nervous system characterized by intolerance without hypotension....
Exertion-related injuries (ERIs) affect Service Members (SM) worldwide with a direct impact on force readiness. Recent evidence has identified that the diagnostic coding of heat-related clinical illnesses can be subjective and prone to errors. Furthermore, ERIs, often have complex presentations impacting multiple organ systems. Optimal management, including establishing correct diagnosis plan for return duty or disability evaluation system referral, frequently requires expertise specialties....
Long-term neurological health risks associated with oil spill cleanup exposures are largely unknown. We aimed to investigate of longer-term conditions among U.S. Coast Guard (USCG) responders the 2010 Deepwater Horizon (DWH) spill.We used data from active duty members DWH Oil Spill Cohort Study (N=45224). Self-reported were ascertained post-deployment surveys. Incident outcomes classified using International Classification Diseases, 9th Revision, codes military encounter records up 5.5 years...
Repeated, high-dose methamphetamine (METH) administrations cause persistent dopaminergic deficits in rodents, nonhuman primates, and humans. In rats, this treatment also causes the formation of high-molecular mass (greater than approximately 120 kDa) dopamine transporter (DAT)-associated complexes, loss DAT monomer immunoreactivity, a decrease function, as assessed striatal synaptosomes prepared 24 h after METH treatment. The present study extends these findings by demonstrating regional...
Autonomic nervous system (ANS) dysfunction as a cause of disease is an increasingly recognized health problem, not only in the field neurology, but also cardiology, gastroenterology, endocrinology, urology, psychiatry, and primary care medicine. Patients may present with myriad symptoms including orthostatic intolerance, recurrent syncope, labile blood pressure, disorders sweating thermoregulation, neurogenic bladder, sexual dysfunction, gastrointestinal dysmotility, pupil abnormalities,...
Abstract Introduction Peripheral nerve injuries are a leading cause of disability within the Military Health System (MHS) patient population. Many peripheral (PNIs) amenable to therapeutic intervention but require timely diagnosis and prompt referral specialty center capable intervention, as functional outcomes directly related duration between injury intervention. Even when appropriately identified, PNI management in MHS is often challenged by lack an established pathway for care...
To describe an intensive mini-fellowship style "Residents' Course" in autonomic medicine.
This paper describes a STEM outreach program for 9-12 grade physics courses. The goal of the is to provide students with hands-on technologically relevant learning activities concepts in electricity and magnetism. three parts this include providing schools appropriate technology, training teachers, developing sufficiently detailed lesson plans. began summer 2011. Being at beginning work progress, very few results are available so itself some
Objective: To report a case of autopsy-proven multiple system atrophy without intra-neuronal alpha-synuclein deposits with profound cardiac sympathetic denervation. Background: Differentiating (MSA) from Parkinson disease orthostatic hypotension (PD+OH) can be very difficult clinically. Neuroimaging studies have indicated that all patients PD+OH denervation, whereas most MSA intact innervation. In immunoreactive (SYN-ir) is found in cytoplasmic inclusion_Lewy bodies_whereas SYN-ir glial...
Objective: Describe the clinical course of patients treated with intravenous immunoglobulin (IVIG) for subacute, progressive, idiopathic autonomic neuropathies (AN). Background: The acute or subacute onset AN without other explanation suggests possibility an immunologic cause some cases. There is limited data regarding chronic immunotherapy autoimmune AN. Methods: We describe four cases a progressive IVIG. Results: 1. A 30-year-old woman presented one year syncope, xerophthalmia and...