- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Non-Invasive Vital Sign Monitoring
- Retinal Diseases and Treatments
- Cardiovascular Health and Disease Prevention
- Corneal surgery and disorders
- Ophthalmology and Visual Impairment Studies
- Retinal and Optic Conditions
- Optical Imaging and Spectroscopy Techniques
- Traumatic Brain Injury and Neurovascular Disturbances
- Intraocular Surgery and Lenses
- Forecasting Techniques and Applications
- Cerebral Venous Sinus Thrombosis
- Retinal Development and Disorders
- Spectroscopy Techniques in Biomedical and Chemical Research
- Cognitive and developmental aspects of mathematical skills
- Ophthalmology and Visual Health Research
- Ocular Diseases and Behçet’s Syndrome
- Statistical and numerical algorithms
- Retinopathy of Prematurity Studies
- Spaceflight effects on biology
- Circadian rhythm and melatonin
- Stock Market Forecasting Methods
- Stellar, planetary, and galactic studies
- Medicinal plant effects and applications
Counties Manukau District Health Board
2015-2024
Lions Eye Institute
2019-2024
The University of Western Australia
2019-2024
University of Otago
2017
Manukau Institute of Technology
2012-2015
Duke University
1999
Purpose Retinal venous pulsation detection is a subjective sign, which varies in elevated intracranial pressure, obstruction and glaucoma. To date no method can objectively measure identify pulsating regions. Method Using high resolution video-recordings of the optic disk retina we measured fluctuating light absorption by haemoglobin during pulsation. Pulsation amplitude was calculated from all regions retinal image video-frames raster pattern. Segmented images were formed selecting with...
Abstract Intracranial pressure (ICP) includes the brain, optic nerve, and spinal cord pressures; it influences blood flow to those structures. Pathological elevation in ICP results structural damage through various mechanisms, which adversely affects outcomes traumatic brain injury stroke. Currently, invasive procedures tap directly into cerebrospinal fluid are required measure this pressure. Recent fluidic engineering modelling analogous ocular vascular suggests that retinal venous pulse...
Pulse wave attenuation characteristics reflect compliance and resistance properties of the vessel wall as well initial pulse generation factors. Recently, it has become possible to measure map retinal amplitudes. Predictable amplitude distribution may allow inferences be made concerning vascular resistance. Twenty-eight eyes from sixteen subjects (8 male 8 female) were examined using modified photoplethysmography with simultaneous ophthalmodynamometry. This allowed assessment pulsation...
To compare the retinal vascular pulsatile characteristics in subjects with normal (ICPn) and high (ICPh) intracranial pressure quantify interactions between intraocular pressure, pulse amplitude Fourier domain.Twenty-one were examined using modified photoplethysmography simultaneous ophthalmodynamometry. A harmonic regression model was fitted to each pixel time-series, used wave parameters including (HRWa). The attenuation measured under different ranges of induced (IOPi), as a function...
Even with the powerful statistical parameters derived from Extreme Gradient Boost (XGB) algorithm, it would be advantageous to define predicted accuracy level of a specific case, particularly when model output is used guide clinical decision-making. The probability density function (PDF) intracranial pressure predictions enables computation definite integral around point estimate, representing event’s within range values. Seven hold-out test cases for external validation an XGB underwent...
Background: Limited data are available on the causes of visual impairment in preschool children New Zealand. We aimed to review demographic and parameters referred Ophthalmology Department, Manukau Super Clinic from vision screening programs South Auckland.Methods: Retrospective medical record 131 children, aged three five years, community‐based Department for further assessment. Medical records were reviewed determine: reason referral; findings ophthalmic assessments; treatment received;...
Spaceflight associated neuro-ocular syndrome (SANS) is common amongst astronauts on long duration space missions and with signs consistent elevated cerebrospinal fluid (CSF) pressure. Additionally, CSF pressure has been found to be in a significant proportion of whom lumbar puncture was performed after successful mission completion. We have developed retinal photoplethysmographic technique measure vein pulsation amplitudes. This enabled the development non-invasive measurement apparatus....
Using the novel imaging method of high-speed modified photoplethysmography we measured retinal venous pulse wave velocity in a single case.A healthy 30-year-old subject underwent (120 frames per second) with simultaneous ophthalmodynamometry at 26 Meditron units. A video optic nerve was analyzed using custom software. harmonic regression model fitted to each pixel time series and used quantify vascular parameters. Retinal pulsation disc observed as complex dynamic wall motion, whereas...
The ideal Intracranial pressure (ICP) estimation method should be accurate, reliable, cost-effective, compact, and associated with minimal morbidity/mortality. To this end several described non-invasive methods in ICP have yielded promising results, however the reliability of these techniques yet to supersede invasive measurement. Over publications, we a novel imaging Modified Photoplethysmography evaluation retinal vascular pulse parameters decomposed Fourier domain, which enables...
To describe a case of intraocular lens (IOL) dystrophic calcification as complication trans-scleral diode laser successfully used to treat post-trabeculectomy cyclodialysis cleft.A 76-year-old male with primary open angle glaucoma and pseudophakia (+19.0D Akreos M160L, Bausch & Lomb) was evaluated for vision impairment 4 months complicated by cleft his right eye. The patient treated laser. After this treatment IOL opacification developed. Slit lamp examination color photography the anterior...
Abstract The carotid-femoral pulse wave velocity (PWV) method is used clinically to determine degrees of stiffness and other indices disease. It believed PWV measurement in retinal vessels may allow early detection diseases. In this paper we present a new non-invasive for estimating PWVs vein segments close the optic disc centre, based on blood column pulsation veins (reflective vessel wall pulsation), using modified photoplethysmography (PPG). An (OD) PPG video acquired spanning three...
Glaucoma is an optic neuropathy resulting in progressive vision loss. It the leading cause of global irreversible blindness. The reported prevalence among population New Zealand 2% over age 40 years. About 10 % those 70 years are diagnosed with this disease. Population-based studies report high rates undiagnosed glaucoma 50 living developed countries remaining and unaware their Clinical diagnosis rests on detection characteristic disc signs. Stereo optic-disc imaging improves intra...
Purpose: The purpose of this study was to describe vessel pulse amplitude characteristics in eyes with central retinal vein occlusion (CRVO), hemiretinal (HVO), normal (N1 N1), and the unaffected contralateral CRVO HVO N1 HVO), as well hemivessels (N2 HVO). Methods: Ophthalmodynamometry estimates blood column amplitudes modified photoplethysmography were timed against cardiac cycles. Harmonic analysis performed on reflectance within 0.25 1 mm from disc center construct maps. Linear mixed...
None declared.
An ideal performance evaluation metric would be predictive, objective, easy to administer, estimate the variance in performance, and provide a confidence interval for level of uncertainty. Time series forecasting may objective metrics predictive mental arithmetic. Addition summation (addition combined with subtraction) using Japanese Soroban computation system was undertaken over 60 days. The median calculation time seconds adding 10 sequential six digit numbers [CTAdd) 63 s (interquartile...
Abstract Background Internal limiting membrane (ILM) drape sign is an important OCT characteristic of Macular telangiectasia type 2 (MacTel 2). Described here a case where masking the ILM occurred with bilateral foveal detachments in patient MacTel 2. Case presentation A 64-year old female was diagnosed 2, four years prior to current on basis demonstrating sign. Fluorescein angiography showed dilated, ectatic capillaries and late phase dye leak. At there gradual visual impairment over two...
None declared.
To describe a case of multiple autoimmune syndrome presenting with type I diabetes, choroidal vitiligo, coeliac disease, pseudohypoparathyroidism, and immune thrombocytopenia purpura (ITP), the latter diagnosed seven years after initial presentation.A 26-year-old female presented bilateral severe diabetic retinopathy. Panretinal photocoagulation (PRP) was initially declined due to poor adherence treatment. Thirty-three months presentation, progression retinal disease proliferative...
To describe pulsations of the retinal arteries detected in course evaluation an exudative non-pulsatile arterial macroaneurysm using near infra-red reflectance videography.A 68-year-old patient underwent slit lamp examination, color imaging, optical coherence tomography, fluorescein videography, short wave-length and infrared fundus autofluorescence left, videography both eyes. A 1309.3 × 955.1 μm lesion with intraretinal hemorrhage edema secondary to a was observed along superior temporal...