A5058925077- Healthcare and Venom Research
- Cholinesterase and Neurodegenerative Diseases
- Epigenetics and DNA Methylation
- Retinopathy of Prematurity Studies
- Blood properties and coagulation
- Ophthalmology and Eye Disorders
- Chemotherapy-induced organ toxicity mitigation
- Reproductive Biology and Fertility
- Testicular diseases and treatments
- Metabolism, Diabetes, and Cancer
- Ovarian cancer diagnosis and treatment
- Metabolism and Genetic Disorders
- Air Quality and Health Impacts
- Reproductive System and Pregnancy
- Redox biology and oxidative stress
- Paraoxonase enzyme and polymorphisms
- Spectroscopy Techniques in Biomedical and Chemical Research
- Adipose Tissue and Metabolism
- Pancreatitis Pathology and Treatment
- Neonatal Respiratory Health Research
- Hemoglobinopathies and Related Disorders
- Retinal Diseases and Treatments
- Diet, Metabolism, and Disease
- Cancer, Hypoxia, and Metabolism
- Microfluidic and Bio-sensing Technologies
Kocaeli Üniversitesi
2018-2022
Kocaeli Sağlık ve Teknoloji Üniversitesi
2022
İstanbul Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi
2014
Background/aim: Methotrexate (MTX), widely used as a drug in cancer, has many adverse effects on tissues. Apocynin (APO) is NADPH oxidase inhibitor and known with antioxidant properties. In this study, we aimed to evaluate the of MTX testicular tissue protective APO at two different doses (20 mg/kg 50 mg/kg) MTX-induced damage.Materials methods: Fifty adult male Wistar albino rats (8 weeks old weighing 200-250 g) were divided into five groups 10 each: 1. saline control, 2. dimethyl sulfoxide...
The aim of the study was to investigate association paraoxonase 1 (PON1) polymorphism, PON1/arylesterase (ARE) activity and oxidative stress index (OSI) in breast cancer (BC) patients with type 2 diabetes (DM).Our group consisted 30 healthy women (HV group) 66 female BC patients. were divided into two groups: those (n=37) without DM (n=29) (BDM NBDM group). Genotyping PON1 Q192R L55M polymorphisms done by polymerase chain reaction (PCR) - restriction fragment length polymorphism (RFLP)...
Testicular torsion is an emergency urological disease, and the treatment immediate surgery. Despite surgery, testicular damage may occur due to reperfusion. Therefore, a medical prevent this be rational idea. We aimed evaluate protective effect of oltipraz in ischaemia/reperfusion damage. Twenty-eight Wistar-Albino rats were randomly divided into four groups. In group, was executed, orchiectomy done 4 hr after detorsion with no treatment. Second group performed torsion; intraperitoneal 50...
Backround. The aim of this study was to examine the expression levels Thioredoxin interacting protein (TXNIP), Vitamin D receptor (VDR), Human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) genes in bladder cancer patients, according clinical staging and determine potential therapeutic targets serum samples. Material Methods. Tissue samples patients who underwent transurethral resection (TUR) between 2017 2018 were obtained. Levels TXNIP, hOGG1, VDR assessed using Real time-polymerase chain...
Evaluation of incompatibility in measurement erythrocyte sedimentation rate by two different modes automated analyzer and demonstration surpassing with a manipulation P oint care test is very difficult to provide standardization benchtop commercial analyzers due the complexities optical systems image retrieval algorithms [1].These automatic should be developed managed feedback from clinicians' aspects observations users.Operators using use various skills techniques evaluate reconstruct...
Acute pancreatitis (AP) is inflammation of pancreas in which enzymatic activity increased. Parasym-pathetic innervation plays an important role several functions pancreas. Botulinum toxin (BTx) might be a tool to suppress the AP.In preliminary experimental study, BTx (15U/kg) was administered directly and intraductal ways. After 10 days, blood amylase, lipase, trypsinogen, insulin, glucagon levels were compared no significant difference seen between groups. Intraductal administration...
Formaldehyde (FA) is a toxic substance used frequently in the field of medicine as well many industrial areas. Especially people working anatomy, histology, and pathology are high risk group because use FA. Studies showing effects FA on cardiovascular system few number. The purpose present study was to investigate exposure, which we believe can cause oxidative stress, heart aorta with various biochemical analyses. A total 24 Wistar Albino rats were our study. We divided into 3 groups Control...
Objective: Unpredictable stress is a common factor that we encounter in our daily lives.In this context, wanted to investigate the morphological effects of chronic unpredictable mild (CUMS) model on rat hippocampus and serum levels brain derived neurotrophic (BDNF) glial fibrillary acidic protein (GFAP). Materials Methods:This study was carried out 16 Wistar albino rats which were divided into control experiment groups.The CUMS protocol applied, structures examined.The GFAP/BDNF measured by...
Abstract Aim : Measurement of blood bilirubin levels is a crucial analysis because the toxic effects on brain tissue, particularly in preterm neonates. The aim this study was to investigate consistency total values obtained by gas analyzer and autoanalyzer. Material Methods In study, we used data 407 pediatric patients from Kocaeli University Medical Faculty Education Research Hospital Central Laboratory System. Total data, provided that it measured simultaneously, ABL 735 Roche Cobas C8000...