Background: There is conflicting evidence as to whether Alzheimer disease (AD) accompanied by loss of retinal ganglion cells. To evaluate this issue, we have used optical coherence tomography (OCT) assess the thickness and volume retina. We also sought correlate our findings with visual function cognitive impairment. Methods: evaluated 28 eyes 14 patients AD 30 15 age-matched control subjects. In these two groups, measured nerve fiber layer (RNFL) thickness, macular OCT, through latency...

Purpose: To evaluate the effects of neuroprotective agents riluzole and resveratrol on survival retinal ganglion cells (RGCs) when administered alone or in combination.Materials methods: Experimental glaucoma was induced by injecting hyaluronic acid into anterior chamber Wistar albino rats weekly for a six-week period. Intraocular pressure measured before immediately after induction. The daily intraperitoneal injections (8 mg/kg) (10 were evaluated compared. After period, dextran...

To evaluate the effects of menopause and hormone replacement therapy (HRT) on quality amount tear, intraocular pressure (IOP) retrobulbar blood flow velocities.Twenty women aged between 40 50 years, free ocular systemic diseases planning to receive HRT were recruited as study group. Twenty-four healthy, age-matched but still menstruating enrolled controls. On first day basal reflex Schirmer test, tear break-up time IOP measurements (at 08.00, 12.00 16.00 h) performed for all groups. second...

To compare the thickness of retinal nerve fiber layer (RNFL), macular volume, and amblyopic eye with those non-amblyopic in patients unilateral strabismic amblyopia using optical coherence tomography (OCT).OCT was performed for 14 who had no neurologic disease. Nine male 5 female patients, whose ages ranged from to 18 years, were enrolled study. The RNFL average analysis program used evaluate mean superior, inferior, temporal, nasal thickness. data all clock quadrants (12 values averaged)...

ABSTRACT In this prospective study, microdrops (mean drop volume 5.6 μl) and commercially available standard drops 35.4 of cyclopentolate, phenylephrine tropicamide's clinical efficacy systemic side effects were compared. Sixty‐one infants requiring diagnostic pupil dilatation studied for pupillary diameter, blood pressure, heart rate skin flushing changes related to the instillation mydriatic drops. Both drugs produced significant increase in diameter compared with baseline (p<0.01)....

To evaluate the short-term effectiveness of intraductal meibomian gland probing using modified Maskin cannulas in patients with obstructive dysfunction.The study prospectively included 58 eyes 30 a diagnosis dysfunction who were refractory to medical treatment for at least 6 months. The divided into 4 groups according number procedures applied. During probing, sterile probes 2, 2.5, 4, and mm length used. A tarsal massage was recommended after treatment. Preoperatively, then postoperatively...

To evaluate the possible predisposing risk factors for late in-the-bag spontaneous IOL dislocations and to study early surgical visual outcomes of repositioning exchange surgeries.Medical records 39 eyes patients who underwent or surgery dislocation between 2010 2018 were reviewed. Possible some characteristics dislocations; surgeries, including acuity, refractive status before after postoperative complications evaluated.The pseudoexfoliation [PEX; 12/39 (30.8%)], previous vitreoretinal...

To evaluate the effect on intraocular pressure (IOP) reduction and safety of ab interno gelatin microstent (XEN 45 Gel Stent; Aquesys, Inc, Aliso Viejo, CA, USA) microincisional glaucoma/cataract surgery in open-angle glaucoma (OAG).In this retrospective study, 30 eyes 25 patients with OAG which underwent XEN implantation combined simultaneous phacoemulsification were clinically evaluated. Clinical outcomes analyzed included IOP, percent IOP reduction, medication use, complications, best...

Purpose To compare the intraocular pressure (IOP) lowering effect and safety of latanoprost, travoprost given every evening, fixed combination dorzolamide + timolol (DTFC) twice daily in pseudoexfoliation glaucoma (PXG). Methods This randomized, prospective, investigator-masked study has been conducted with 50 PXG patients. Patients were assigned to one three groups: 0.004%, 2%+timolol 0.5%, or latanoprost 0.005% for 6 months. At baseline 0.5, 1, 2, 3, 4, 5, months therapy, IOP (8 am, 10 4...

Single-dose subconjunctival platelet-rich plasma (sPRP) injections with or without antibiotic treatment were investigated for their effect on corneal epithelial wound healing in a rabbit model.A total of 24 rabbits used this study. After collecting intracardiac blood samples from 16 rabbits, was obtained by centrifugation. Animals divided into 3 groups. A mechanical defect 7-mm diameter created the central cornea right eye each animal. Group 1 (n = 8) received only sPRP, whereas group 2 sPRP...

To evaluate the retinal nerve fiber layer (RNFL) thickness in patients with unilateral pseudoexfoliation syndrome (PXS) without glaucoma by using optical coherence tomography (OCT).22 PXS were evaluated. Group 1 included eyes pseudoexfoliation, group 2 fellow eyes; 18 age-matched normal control assessed 3. The mean and segmental RNFL their was compared to subject eyes.The significantly thinner than controls all quadrants except nasal quadrant regard analysis (p < 0.05). This loss apparent at...

Background: To investigate the acute effect of caffeine on intraocular pressure and retrobulbar blood flow velocity. Methods: In this randomized, double-masked, placebo-controlled, prospective study, we examined effects single 300-mg oral administration arteries' hemodynamics by using color Doppler ultrasonography imaging in healthy human volunteers. The subjects were divided into two groups; group 1 received a tablet 2 placebo. Measurements obtained eyes at baseline, hr after ingestion...

Purpose: To compare the effects of bevacizumab applied either subconjunctivally or topically, in a rat model corneal neovascularization induced by alkali burn. Methods: The right corneas 24 Wistar-Albino rats were cauterized with silver nitrate sticks. divided randomly and equally into three groups: no treatment control (n=8), subconjunctival topical (n=8). Immediately following cauterization, group was treated 0.05 ml (1.25 mg) injection. 10 mg/ml twice daily, received saline injections...

To evaluate ischemic changes in brain magnetic resonance images patients with pseudoexfoliation syndrome (PXS) and glaucoma (PXG) compare them age- sex-matched control subjects.This case-control study involved 16 consecutive PXS, 21 PXG 18 healthy subjects. Each subject underwent a comprehensive ophthalmological examination. In all participants, an axial T(1)-, T(2)- proton-density-weighted coronal cerebral 1.5-tesla imaging (MRI) scan was made. White matter hyperintensities (WMH) were...

To determine the incidence and severity of hearing loss in different frequencies patients with pseudoexfoliation. Furthermore, possible links between homocysteine pseudoexfoliation were evaluated.Seventy-five consecutive 75 sex- age-matched subjects without as control group included this prospective case-control study. Pure-tone audiometry was obtained all both groups. Blood samples from 70 after overnight fasting for levels analyzed by routine laboratory measurements.Fifty-two (69%) 39...

To detect abnormalities of the optic nerve in patients with thyroid orbitopathy using diffusion tensor MRI.Twenty-eight Graves prospectively underwent imaging scanning. A full ophthalmic examination including visual acuity, intraocular pressure, fundoscopy, and field analysis was performed. Clinical activity scores were also calculated. Fractional anisotropy (FA) mean diffusivity values compared age sex-matched healthy control subjects.The FA decreased increased significantly subjects (p <...

This study aimed to evaluate subclinical retinal microvascular changes with OCTA in juvenile systemic lupus erythematosus (JSLE) patients without ocular involvement.Ten eyes of 10 JSLE and 13 age sex-matched healthy controls (HCs) were enrolled. The superficial (SCP) deep capillary plexus (DCP), FAZ parameters, the flow area outer retina, choriocapillaris evaluated using OCTA.All vessel density (VD) parameters DCP significantly lower group compared HCs. There was no significant difference...