A5020597496- Tryptophan and brain disorders
- Neuroscience and Neuropharmacology Research
- Bipolar Disorder and Treatment
- Neuroinflammation and Neurodegeneration Mechanisms
- Stress Responses and Cortisol
- Maternal Mental Health During Pregnancy and Postpartum
- Cholinesterase and Neurodegenerative Diseases
- Treatment of Major Depression
- Neurotransmitter Receptor Influence on Behavior
- Electrolyte and hormonal disorders
University of Ghana
2022
Postpartum depression is a mood disorder that affects about 9-20% of women after child birth. Reports suggest gestational iron deficiency can cause deficit in behavioral, cognitive and affective functions precipitate depressive symptoms mothers during the postpartum period. The present study examined effect supplementation on behavior period rat model.Female Sprague-Dawley rats were crossed. Pregnant received iron, fluoxetine, desferrioxamine or vehicle throughout gestation. During period,...
Background/Aim: Depression-related aggression is linked to serotonin (5-HT) and dendritic spine alterations. Although Mallotus oppositifolius extract (MOE) has potential for reducing this effect, its specific role remains uncertain. Herein, we evaluated associated alterations in the brain. Methods: A standard resident-intruder model of para-chlorophenylalanine (pCPA)-induced depression-associated male ICR mice was used. The resident received pCPA (300 mg/kg, i. p.) 3 consecutive days while...
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<ns3:p>Background Natural remedies with neuroprotective effect are useful in neuroinflammation-associated depression. Although <ns3:italic>Mallotus oppositifolius</ns3:italic> extract (MOE) has previously demonstrated antidepressant and anti-inflammatory properties, its remains unknown. Thus, the study evaluated of MOE on lipopolysaccharide (LPS)-induced depression mice. Methods Antidepressant-like (10 – 100 mg/kg), fluoxetine (20 mg/kg) minocycline (50 was established naïve Institute Cancer...
<ns3:p><ns3:bold>Background:</ns3:bold> Natural remedies with neuroprotective effect are useful in neuroinflammation-associated depression. Although <ns3:italic>Mallotus oppositifolius</ns3:italic> extract (MOE) has previously demonstrated antidepressant and anti-inflammatory properties, its remains unknown. Thus, the study evaluated of MOE on lipopolysaccharide (LPS)-induced depression mice.</ns3:p><ns3:p> <ns3:bold>Methods:</ns3:bold> Antidepressant-like (10 - 100 mg/kg), fluoxetine (20...