A5042122723- Antibiotics Pharmacokinetics and Efficacy
- Malaria Research and Control
- Pneumonia and Respiratory Infections
- COVID-19 epidemiological studies
- Advanced Drug Delivery Systems
- Pharmacological Effects and Toxicity Studies
- Bacterial Identification and Susceptibility Testing
- Genomics, phytochemicals, and oxidative stress
- Phytochemicals and Antioxidant Activities
- Antibiotic Use and Resistance
- Pharmaceutical Practices and Patient Outcomes
- Advanced Biosensing Techniques and Applications
- Traditional and Medicinal Uses of Annonaceae
- Pharmacogenetics and Drug Metabolism
- Viral Infections and Outbreaks Research
- Tryptophan and brain disorders
- Diabetes and associated disorders
- Renal Diseases and Glomerulopathies
- COVID-19 Pandemic Impacts
- COVID-19 Clinical Research Studies
- Patient Safety and Medication Errors
- Advanced Proteomics Techniques and Applications
- Research on Leishmaniasis Studies
- Neonatal and Maternal Infections
- Pharmaceutical studies and practices
University of Ghana
2015-2025
Korle Bu Teaching Hospital
2012-2023
Noguchi Memorial Institute for Medical Research
2019-2020
The novel coronavirus, SARS-CoV-2, which causes COVID-19, is seen world-wide. In developing countries, adequate health facilities and staff numbers are a concern. Ghana recorded its first 2 cases of COVID-19 on 12 March 2020. On 30 2020, partial lockdown for 14 days was imposed later extended along with other measures. By the end initial lockdown, 19 April an estimated 86,000 people had been traced 68,591 tests performed. Of tests, there were 1,042 (1.5%) positive cases, 9 deaths, 99...
Data suggest malfunctioning mitochondria reduce oxidation and adenosine triphosphate (ATP) production, disrupting insulin signalling. Cytochrome c (CC), acylcarnitine (AC) citrate synthase (CS) are essential components of the machinery can be used as reliable biomarkers mitochondrial dysfunction. This study aimed to determine whether (AC, CS CC) altered in individuals with type 2 diabetes mellitus (T2DM) examine association between these resistance.
Purpose: This study presents a novel and sustainable approach to cancer therapy by combining halloysite nanotubes (HNTs), green‐synthesized copper oxide (CuO) nanoparticles, curcumin (CUR). We demonstrate that the green synthesis of CuO when combined with CUR incorporated into HNTs, enhances delivery anticancer effects CUR. innovative complex could address some critical limitations current therapies such as poor pharmacokinetics drug resistance providing controlled release mechanism...
Nymphaea lotus L. (N. lotus) is an aquatic plant with anecdotal reports suggesting its use in the traditional management of cancer. However, there a paucity data on antioxidant, anti-inflammatory and cytotoxic properties N. relation to phytochemical elemental contents. This study aimed at determining hydro-ethanolic extract leaves (NLE), phenolic, flavonoid constituents.The antioxidant property NLE was determined using total phenolic flavonoid, DPPH radical scavenging, lipid peroxidation...
In most resource-poor settings, there is a paucity of data on self-medication and possible factors that influence this practice. The current study assesses among the people Akuse, rural setting in Eastern Region Ghana.A quantitative cross-sectional was carried out Akuse from 4th January 2016 to 27th February 2016. Using questionnaire, interviews were conducted assess self-medication: class drugs taken, sources drugs, knowledge potential adverse effects, others.Of 363 participants enrolled,...
Introduction: irrational or inappropriate prescribing of antibiotics is a major problem in healthcare and leads to antibiotic resistance. There the need understand patterns stewardship health facilities support appropriate use. A study was carried out evaluate pattern at Ghana Police Hospital using National Standard Treatment Guidelines (STG) World Health Organization (WHO) indicators.
Background and Objectives: Widespread empiric use of antibiotics exists especially in developing countries. This is a concern since inappropriate antibiotics, including their extended use, will increase resistance rates. Consequently, there need to evaluate antibiotic utilisation across healthcare sectors improve future use. includes ceftriaxone, widely used among hospitals those Ghana.Methods: A cross-sectional study the appropriateness ceftriaxone prescribing leading hospital Ghana....
: Pangdahai (matured, ripened, and dried seeds of Scaphium affine (Mast.) Pierre) is widely used in managing several diseases countries like China, Vietnam, Japan, India. This study evaluated the anti-inflammatory effects crude extracts (ethanol aqueous) isolated compounds Pangdahai. Xylene-induced ear edema mice, carrageenan-induced paw rats, nitric oxide (NO) assay were to evaluate screen from ethanolic TNF-α IL-1β levels tissues rat foot determined by ELISA. The cytotoxicity was also MTT...
Diabetes mellitus is a growing public health problem in many countries including Ghana. Adherence to drugs, especially among patients with type 2 diabetes (T2DM) often poor some resource-poor settings. The objective of this study was assess adherence oral hypoglycemic drugs and factors that affect T2DM the Volta Region Ghana.The cross-sectional conducted 400 attending diabetic clinics at 4 randomly selected hospitals Ghana between January 10 March 30, 2015. Patients were interviewed using...
Abstract Introduction Insulin resistance (IR) is one of the common chronic metabolic disorders in Africa and elsewhere. Accumulation lipids body may be due to an imbalance metabolism lipids, glucose proteins. Ceramides are a sphingolipid class that biologically active vital production more complex lipids. Circulating ceramides thought have role development obesity‐related IR, although precise involvement remains unclear. Aim To investigate impact circulating ceramide on IR adiposity people...