A5070980865- Trace Elements in Health
- Iron Metabolism and Disorders
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Plant Toxicity and Pharmacological Properties
- Urinary Bladder and Prostate Research
- Ethnobotanical and Medicinal Plants Studies
- Natural Antidiabetic Agents Studies
- Bioactive Natural Diterpenoids Research
- Diabetes Management and Research
- Antioxidant Activity and Oxidative Stress
- Phytochemistry and Bioactivity Studies
- Carcinogens and Genotoxicity Assessment
- Phytochemistry and Biological Activities
- Malaria Research and Control
- Pharmacological Effects of Natural Compounds
- Essential Oils and Antimicrobial Activity
- Heavy Metal Exposure and Toxicity
- HIV-related health complications and treatments
- COVID-19 epidemiological studies
- Traditional and Medicinal Uses of Annonaceae
- Child Nutrition and Water Access
- Birth, Development, and Health
- Hemoglobinopathies and Related Disorders
- COVID-19 and healthcare impacts
- Clinical Laboratory Practices and Quality Control
University of Ghana
2016-2025
University of Health and Allied Sciences
2014-2024
University of Chicago
2024
Korle Bu Teaching Hospital
2012-2023
Gazipur Agricultural University
2020
Bangladesh Agricultural University
2020
University of Bahrain
2013
University of the Witwatersrand
2005-2010
Cancer Association of South Africa
2007
Chris Hani Baragwanath Hospital
2005-2007
The novel coronavirus, SARS-CoV-2, which causes COVID-19, is seen world-wide. In developing countries, adequate health facilities and staff numbers are a concern. Ghana recorded its first 2 cases of COVID-19 on 12 March 2020. On 30 2020, partial lockdown for 14 days was imposed later extended along with other measures. By the end initial lockdown, 19 April an estimated 86,000 people had been traced 68,591 tests performed. Of tests, there were 1,042 (1.5%) positive cases, 9 deaths, 99...
Background: Globally, the application of medicinal plants in management acute and chronic wounds can be considered a common occurrence most traditional medicine practices. In view this, many tropical subtropical regions have been screened for their wound-healing activities. Consequently, having antimicrobial activity against multidrug-resistant (MD-R) pathogens great assets. Therefore, this study evaluated ethanolic aqueous extracts five (Psidium guajava, Myrianthus arboreus, Alchornea...
Acute toxicity studies of aqueous leaf extract Phyllanthus niruri is a plant with medicinal properties. It often used to treat mild malaria and the elimination renal stones. However, on its are scarce. The study was carried out determine if P. administered female Sprague-Dawley rats would illicit evidence toxicity. Fifteen weighing 150-200 g were divided into 3 groups. Rats in Group 1 given single low dose (LD) 2 000 mg/kg b.w. by oral gavage within 24 hrs. high (HD) 5 not any but drinking...
Effect of hormonal contraceptives on lipid profile and the risk indices for cardiovascular disease in a Ghanaian community George A Asare,1 Sheila Santa,1 Robert Ngala,2 Bernice Asiedu,1 Daniel Afriyie,3 Albert GB Amoah4 1Department Medical Laboratory Sciences, University Ghana School Allied Health Sciences (SAHS), Korle-bu, Ghana; 2Department Molecular Medicine, Kwame Nkrumah Science Technology, Kumasi, 3Department Pharmacology, 4Department School, Background: Hormonal (HCs) have been shown...
The etiology of benign prostatic hyperplasia (BPH) remains a mystery to scientists; estrogen/androgen imbalance in aged men has been implicated.Thirty (30) apparently healthy and newly diagnosed BPH patients were recruited from the Ghana Police Hospital. Lower urinary tract syndrome (LUTS) prostate volume assessed via symptom score sheet (IPSS) abdominopelvic scan, respectively. Laboratory assays for total specific antigen (tPSA) hormones [androstenedione (AED), testosterone (T),...
Background Male infertility is a significant global public health issue, with modifiable lifestyle factors such as smoking, obesity, and psychological stress contributing to impaired semen quality hormonal dysregulation. This study investigates the relationships between factors, reproductive hormones, in Ghanaian males attending an IVF clinic. Methods A cross-sectional was conducted 212 male participants recruited from fertility clinic Ghana. Lifestyle were assessed using standardized...
Background: The safety of combining tamsulosin (an allopathic drug) and Croton membranaceus aqueous extract, a medicinal plant for managing benign prostatic hyperplasia (BPH), was investigated. Methods: roots CM were used processed into water extract by maceration decoction. Thirty‐five Sprague Dawley rats divided seven groups five each. Groups 2–7 orchidectomy/testosterone injections BPH‐induced. Group 1 designated as the control group. 2 model group (untreated). 3 treated with 0.03 mg/kg...
Annona muricata L. has been reported to possess antitumor and antiproliferative properties. Not much work done on its effect BPH-1 cell lines, no in vivo studies targeting the prostate organ exist. The study determined of A human cells organ.The MTT assay was performed using aqueous leaf extract muricata. Cells (1 × 10(5) per well) were challenged with 0.5, 1.0, 1.5 mg/mL for 24, 48, 72 hours. Cell proliferation morphology examined microscopically. 10(4) seeded into 6-well plates incubated...
Phyllanthus niruri is a medicinal plant (commonly known as stone breaker) found in the tropics and other parts of world. It for its capacity to block formation calcium oxalate crystals kidney urolithiasis. This has been used treat hyperglycemia, hypertension, pain, mild cases malaria. We examined geno-, cyto- overall toxicity P. whole ethanolic extract. The extract was administered single dose 30 or 300 mg/kg laboratory rats by gavage, accompanied negative (0.9% saline) positive (10 mg/mL...
Introduction Attempting to curb the rising epidemic of hypertension, South Africa implemented legislation in June 2016 mandating maximum sodium levels a range manufactured foods that contribute significantly population salt intake. This natural experiment, comparing two African countries with and without legislation, will provide timely information on impact legislative approaches addressing food supply improve blood pressure populations. article outlines design this ongoing prospective...
Although excess hepatic iron in hereditary haemochromatosis and dietary overload the African causes hepatocellular carcinoma, it usually does so presence of cirrhosis. A direct hepatocarcinogenic effect has not been proved. Moreover, an animal model carcinoma induced by available. The aim this study was to develop such a use ascertain whether is directly hepatocarcinogenic. Sixty Wistar albino rats were fed chow diet 60 same supplemented initially with 2% carbonyl for 12 months, followed...
Malaria continues to be a great public health concern due the significant mortality and morbidity associated with disease especially in developing countries. Microparticles (MPs), also called plasma membrane derived extracellular vesicles (PMEVs) are subcellular structures that generated when they bud off membrane. They can found healthy individuals but numbers tend increase pathological conditions including malaria. Although, various studies have been carried out on protein content of...
Abstract Cardiovascular diseases ( CVD s) are listed as one of the main causes mortality and morbidity by World Health Organization. The Heart Federation lists overweight/obesity, blood lipid profile, pressure some modifiable risk factors to developing s. This study sought determine prevalence these among University Ghana students. One hundred twenty students were sampled for study. Lipid profile parameters such high‐density lipoprotein HDL ), total cholesterol TC triglycerides TG ) measured...
Introduction: reports of increasing resistance uropathogens to antimicrobials is global concern. Culture and drug susceptibility tests remain a vital guide effective therapy. The aim this study was determine the pattern isolated ciprofloxacin at Ghana Police Hospital.
Several flavonoids isolated from certain plants have demonstrated antiplasmodial activity, after their initial indigenous use in malaria treatment. Cocoa has been found to be a rich food source of comparison with many common foods and beverages. The aim this work was investigate the vitro activity natural cocoa powder on growth Plasmodium falciparum. Prepared crude methanol extract partitioned successively petroleum ether, ethyl acetate, chloroform, butanol. Total flavonoid concentration...