A5039451362- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Multiple Sclerosis Research Studies
- Advanced Neuroimaging Techniques and Applications
- Organ Transplantation Techniques and Outcomes
- Infectious Encephalopathies and Encephalitis
- Advanced NMR Techniques and Applications
- Cardiovascular and exercise physiology
- MRI in cancer diagnosis
- Biochemical effects in animals
- Ultrasound Imaging and Elastography
- Metabolism and Genetic Disorders
- Cytomegalovirus and herpesvirus research
- Glioma Diagnosis and Treatment
- HIV Research and Treatment
- Pancreatic function and diabetes
- Ultrasound and Hyperthermia Applications
- Epilepsy research and treatment
- Functional Brain Connectivity Studies
- Hereditary Neurological Disorders
- Biochemical and Molecular Research
- RNA regulation and disease
- Dialysis and Renal Disease Management
- Cerebrospinal fluid and hydrocephalus
Vall d'Hebron Hospital Universitari
2009-2025
Universitat Autònoma de Barcelona
2003-2022
Vall d'Hebron Institut de Recerca
2013-2021
Resonance Research (United States)
2002-2017
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2007-2014
Instituto de Salud Carlos III
2009-2012
Hospital Materno-Infantil
2012
Escuela Nacional de Sanidad
2011
Medicina
2011
Universitat Politècnica de Catalunya
2011
Physiologic adaptations after an 8-wk endurance training program were examined in 13 patients with chronic obstructive pulmonary disease (COPD) (age, 64 ± 4 [SD] yr; FEV1, 43 9% pred; PaO2 , 72 8 mm Hg; and PaCO2 36 2 Hg) eight healthy sedentary control subjects (61 yr). Both pre- post-training studies included: (1) whole-body oxygen consumption (V˙ o 2) one-leg O uptake 2leg) during exercise; (2) intracellular pH (pHi) inorganic phosphate to phosphocreatine ratio ([Pi]/[PCr]) half-time of...
Hepatic encephalopathy (HE) is a common complication of cirrhosis that associated with brain atrophy and may participate in impaired cognitive function after liver transplantation. This study analyzes the relationship HE volume A total 52 consecutive patients (24 alcohol abuse, 24 prior HE, 14 diabetes mellitus) completed neuropsychological assessment before transplantation again, 6 to 12 months In who underwent posttransplant assessment, magnetic resonance imaging was performed addition,...
Disease activity in multiple sclerosis (MS) is strongly linked to the formation of new lesions, which involves a complex sequence inflammatory, degenerative, and reparative processes. Conventional magnetic resonance imaging (MRI) techniques, such as T2-weighted gadolinium-enhanced T1-weighted sequences, are highly sensitive demonstrating spatial temporal dissemination demyelinating plaques brain spinal cord. Hence, these techniques can provide quantitative assessment disease patients with...
Hepatic encephalopathy can arise from portal-systemic shunting in the absence of intrinsic liver disease. However, there are few descriptions this form encephalopathy. Portal vein thrombosis is an infrequent disease that causes shunting. Episodic hepatic has been described patients with portal thrombosis, but it not known if these develop minimal We designed a study to investigate neurological consequences without cirrhosis and no clinical signs For purpose, 10 underwent neuropsychological...
Background: Cognitive impairment is frequent in multiple sclerosis (MS) and lacks effective treatment. rehabilitation widely applied neurorehabilitation settings. Functional magnetic resonance imaging (fMRI) may help investigating changes brain activity provide a tool to assess the efficacy of rehabilitation. Aim: To investigate effect on as measured by fMRI cognitive programme patients with MS impairment. Method: Fifteen five healthy subjects were recruited. Neuropsychological assessments...
<b>BACKGROUND AND PURPOSE:</b> Differentiating between tumors and pseudotumoral lesions by conventional MR imaging may be a challenging question. This study aims to evaluate the potential usefulness added value that single-voxel proton spectroscopy could provide on this discrimination. <b>MATERIALS METHODS:</b> A total of 84 solid brain were retrospectively included in (68 glial 16 lesions). Single-voxel spectra at TE 30 ms (short TE) 136 (long available all cases. Two groups defined:...
PURPOSE: To assess the utility of proton magnetic resonance (MR) spectroscopy in clinical categorization primitive neuroectodermal tumors (PNETs) adults. MATERIALS AND METHODS: In vivo MR was performed with an echo time 136 msec nine adults PNET, and findings were retrospectively compared spectroscopic 22 meningiomas, 12 low-grade astrocytomas, eight anaplastic 23 glioblastomas, 21 metastases. Nine resonances semiquantitatively evaluated. Statistical analysis by using Kruskal-Wallis...
Focal T2-weighted white matter lesions (WML) on brain magnetic resonance imaging (MRI), mimicking those seen in cerebrovascular small-vessel disease described patients with persistent hepatic encephalopathy, decreased volume the improvement of encephalopathy. This outcome has been interpreted as a decrease edema that it is proposed to be involved pathogenesis We designed study further investigate potential changes focal WML brains cirrhosis following liver transplantation and relationship...
<b><i><i>Objective:</i></i></b> To determine whether edema can be assessed by MRI using T2-weighted signal intensity of hemispheric white matter in cirrhotic patients. <b><i><i>Methods:</i></i></b> Fast-FLAIR and magnetization transfer images were obtained before (24) after (11) liver transplantation. abnormalities on baseline scans their time-course changes analyzed compared with MT ratios (MTR). <b><i><i>Results:</i></i></b> showed faint to substantial, bilateral, symmetric increased along...
Brain magnetic resonance (MR) study has shown metabolic abnormalities and changes in water distribution of the brain tissue that may relate to pathogenesis hepatic encephalopathy (HE). We designed a investigate disturbances metabolites during episodic HE using 3-T MR scanner. Cirrhotic patients with different grades underwent hospitalization ( n = 18). The was repeated at 6 weeks' follow-up 14). results were compared those group healthy volunteers 8). During HE, diffusion-weighted imaging...
Synthetic MRI (SyMRI) is a short-time acquisition sequence that generates different contrast-weighted images based on the measurement of tissue properties and provides quantitative volumetric, relaxation, myelin maps. It has been used as an alternative to conventional sequences in relapsing-remitting MS for detecting focal lesions volumetric analysis. This study aimed find SyMRI variable associated with Expanded Disability Status Scale (EDSS) ≥ 6 progressive patients. Twenty-four patients...
Abstract Twenty‐three pairs of normal mucosa and colonic adenocarcinoma biopsy specimens have been examined in this pilot study by 1 H NMR spectroscopy at 9.4 T to determine whether it was possible find spectral malignancy markers. The 3.2 ppm (trimethylamine‐containing compounds)/0.9 (methyl fatty acids) resonance intensity ratio water suppressed spectra, proposed other authors as a marker, results our hands, using areas, partial overlap between tumor values, which reduces its diagnostic...
From July 1974 to January 1986, 50 patients underwent conservative repair for rheumatic aortic valvular disease at our institution. Eleven were male and 39 female, with an average age of 39.5 years (range 17-57). The lesion was associated in all cases a predominant mitral lesion. Twenty-five also had tricuspid which surgically treated 17. Twenty-six regurgitation 24, mixed surgical techniques used were: (1) commissurotomy, (2) annuloplasty, (3) cusp free edge unfolding (4) supra-aortic crest...