A5051079557- Drug Solubulity and Delivery Systems
- Analytical Methods in Pharmaceuticals
- Advanced Drug Delivery Systems
- Crystallization and Solubility Studies
- Analytical Chemistry and Chromatography
- Nanoparticle-Based Drug Delivery
- Advancements in Transdermal Drug Delivery
- Inhalation and Respiratory Drug Delivery
- Antibiotics Pharmacokinetics and Efficacy
- Glioma Diagnosis and Treatment
- Pesticide Residue Analysis and Safety
- Microencapsulation and Drying Processes
- Essential Oils and Antimicrobial Activity
- biodegradable polymer synthesis and properties
- Nanoparticles: synthesis and applications
- Lipid Membrane Structure and Behavior
- Cholinesterase and Neurodegenerative Diseases
- Surfactants and Colloidal Systems
- Electrospun Nanofibers in Biomedical Applications
- Graphene and Nanomaterials Applications
- Polysaccharides Composition and Applications
- Brain Metastases and Treatment
- Pharmaceutical Quality and Counterfeiting
- Silk-based biomaterials and applications
- Chemical synthesis and pharmacological studies
B. K. Mody Government Pharmacy College
2015-2025
Government Medical College
2015-2025
Government of Gujarat
2024
Gujarat Technological University
2023-2024
Baptist Hospital of Miami
2021
Baptist Health South Florida
2021
Cornell University
2020
Weill Cornell Medicine
2020
NewYork–Presbyterian Hospital
2020
Presbyterian Hospital
2020
Biogenic metallic nanoparticles (BMNPs) are nanostructure materials synthesized through biological processes that have gained significant attention due to their small size and high surface area-to-volume ratio. BMNPs several advantages over chemically ones eco-friendly synthesis regimen, sustainability, biocompatibility, diverse multifarious biomedical applications. Moreover, the superior cytocompatibility stability capping layer (MNPs), reduces like hood of toxicity side effects, making...
<title>Abstract</title> A specific, precise, accurate, robust, cost-effective and reproducible diode array detector based RP-HPLC method was developed validated for quantitative analysis of Pantoprazole sodium Aspirin in synthetic mixture. In drugs were separated by Inertsil C18 ODS (250 × 4.7mm, 5µm), utilizing a mobile phase buffer(0.05 m potassium dihydrogen phosphate pH 3 Adjusted using 10% Orthophosphoric acid) : Acetonitrile (60 40%) at temperature(TEMP) 30º C, flow rate 1 mL/min,...
Even when treated with aggressive current therapies, most patients glioblastoma survive less than two years. Rapid tumor growth, an invasive nature, and the blood-brain barrier, which limits penetration of large molecules into brain, all contribute to poor response associated conventional therapies. Immunotherapy has emerged as a therapeutic approach that may overcome these challenges. We recently reported single-walled carbon nanotubes (SWCNTs) can be used dramatically increase...
The aim of this investigation was to improve the dissolution properties water-insoluble drug ezetimibe (EZE) and potentially bioavailability.A combination melt adsorption techniques employed for preparation solid dispersions.PEG 4000, PEG 6000, Gelucire 44/14 were used as hydrophilic carriers, lactose monohydrate an adsorbent.Phase solubility curves are A L type, indicating a linear relationship between carrier concentration.Dissolution studies reveal improvement in vitro...
Analytical methods are required to be developed at different stages of the pharmaceutical product life cycle. The concept QbD can extended analytical method development known as quality by design (AQbD). Quality is a systematic approach that begins with predefined objects and emphasizes process understanding helps in drug development. concepts described ICH Q8- Q11, commonly referred (QbD), have also been applied methods. benefits applying principle include identifying minimizing sources...
Stability-indicating methods are crucial analytical techniques that aim to evaluate the stability of a drug substance or product over time. They designed detect any alterations in drug's chemical, physical, biological characteristics may occur during storage, transportation, and usage. These modifications can significantly impact safety effectiveness, making testing an integral part pharmaceutical quality control. The stability-indicating used identify degradation products drug, quantify...
The objective of the present investigation was to develop and characterize self-nanoemulsifying drug delivery system (SNEDDS) glimepiride, a poorly soluble drug. Solubility glimepiride in various vehicles determined, ternary phase diagrams were constructed using suitable oil, surfactant, cosurfactant find out efficient self-emulsification system. A three factor, level Box-Behnken statistical design employed explore main interaction effect independent variables, namely X1 (amount Capmul MCM),...
Abstract Objectives The aim of this study was to develop and optimize levofloxacin loaded PLGA nanoparticles (LN) for pulmonary delivery employing screening experimental design evaluate their in-vitro in-vivo performance. objective achieve Mass Median Aerodynamic Diameter (MMAD) LN less than 5μm, sustain the drug release up 120 h a higher AUC/MIC at site action. Methods were prepared by modified emulsion solvent evaporation technique high speed homogenization, probe sonication subsequent...