A5062133559- Atrial Fibrillation Management and Outcomes
- Cytokine Signaling Pathways and Interactions
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Function and Risk Factors
- Apelin-related biomedical research
- Nitric Oxide and Endothelin Effects
- Neurological Disorders and Treatments
- Atherosclerosis and Cardiovascular Diseases
- Adipokines, Inflammation, and Metabolic Diseases
- Biomarkers in Disease Mechanisms
- Cancer, Lipids, and Metabolism
- Cholesterol and Lipid Metabolism
- Biochemical Acid Research Studies
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Healthcare Systems and Public Health
- Electrolyte and hormonal disorders
- Chronic Kidney Disease and Diabetes
- Cardiovascular Disease and Adiposity
- Lipoproteins and Cardiovascular Health
- Cardiomyopathy and Myosin Studies
- Retinal Imaging and Analysis
- Steroid Chemistry and Biochemistry
- Paraoxonase enzyme and polymorphisms
City Clinical Hospital
2013-2019
Central State Medical Academy
2018-2019
Institute of Experimental Cardiology
2015
State Research Center of the Russian Federation
2010
Aim . To analyze possible association of the risk adverse outcomes development in patients post acute coronary episode (ACS), with polymorphism gene TNF. Material and methods study, included, that were under observation 2 registry studies ORACLE I II (Exacerbation heart disease: logic-probability ways course prediction treatment optimization). In overall, 2012 ACS assessed. Mean age 64,7±12,69 y.o. There 1205 males (59,8%) 807 females (40,2%). 741 (36,8%) included ST elevation ACS, 1271...
The study performed WGS in 74 patients with PAH using the MGI DNBSEQ platform. bwa-mem, MarkDuplicates, GATK HaplotypeCaller and VEP tools dbNSFP SpliceAI were used for analysis. Six known (5 pathogenic, 1 likely pathogenic) de novo (likely SNPs identified. identified create stop signals or alter splicing of BMPR2 gene, which is associated pathogenesis PAH.
We tested possibility of the use apelin-12 as a biomarker chronic heart failure (CHF). The study comprised 108 patients with I-IV functional class CHF various etiology (ischemic disease, dilation cardiomyopathy) and 40 healthy volunteers. Blood samples were taken at hospital admission before prescription pharmacological therapy. In all we carried out echocardiography calculation end-diastolic end-systolic volumes (EDV, ESV) ejection fraction (EF). plasma concentration was compared market...
The aim of work: to study psychosomatic disorders manifesting in connection with the circumstances pulmonary hypertension (PH), evaluate impact pathology on features internal picture disease formation, level compliance, determine need for psychocorrectional measures. Material and methods: there were 40 patients PH 1st 4th groups admitted consistently from September 2017 2018 City Clinical Hospital №51 Moscow Health Department. following parameters evaluated: frequency, spectrum severity...
Analysis of the current literature data on use warfarin in patients with cardioembolic stroke is presented. Cardioembolic pathology and particularities this condition therapy antithrombotic medications are shown details. Possibility to apply thrombolysis during treatment anticoagulants after discussed.
Review of current ideas about the role acetylsalicylic acid (ASA) in primary prevention cardiovascular disease is presented. Data on reduction malignant neoplasms incidence rate long-term use drug, as well prospects for further study ASA are considered.
The possibilities and evidence base of clopidogrel use in clinical practice are discussed. Data about the main trails on efficacy treatment second prevention atherothrombotic complications presented. results comparative original generic also reviewed.
Objective: The purpose of our work was to analyze the possible association clinical and genetic factors with development strokes in patients coronary heart disease. Design method: We included study 1193 acute syndrome (63,2% men, mean age 61,1 ± 0,34 yaers). 81,5% had essential hypertension, 14,6% - diabetes, 38,5% were smokers, 16,4% anamnesis atrial fibrillation. Follow up started on day 10 stable state after index event. Inclusion into performed 2004–2007. Mean duration follow 664,9 days,...
Purpose: to analyze possible associations of clinical and genetic factors with development ischemic stroke after exacerbation heart disease (IHD). Materials methods: RAe Russian multicenter study aimed at assessment risk unfavorable outcomes IHD "Exacerbation IHD: logical probabilistic ways course prognostication for optimization treatment” (meaning Cyrillic acronym - oracle) was conducted in 16 centers 7 cities Russia. We included into the 1 208 patients unstable angina ST-elevation or...