- Infectious Diseases and Tuberculosis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Hematological disorders and diagnostics
- Asthma and respiratory diseases
- Long-Term Effects of COVID-19
- Diagnosis and treatment of tuberculosis
- Obstructive Sleep Apnea Research
- Pulmonary Hypertension Research and Treatments
- Pleural and Pulmonary Diseases
- Vasculitis and related conditions
- Metastasis and carcinoma case studies
- Ocular Diseases and Behçet’s Syndrome
- Cardiovascular and Diving-Related Complications
- Respiratory Support and Mechanisms
- Cardiovascular Health and Disease Prevention
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Congenital Diaphragmatic Hernia Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Inhalation and Respiratory Drug Delivery
- Lung Cancer Diagnosis and Treatment
- Sarcoidosis and Beryllium Toxicity Research
- Cardiovascular Disease and Adiposity
- Lung Cancer Treatments and Mutations
King George's Medical University
2016-2025
Santokba Durlabhji Memorial hospital
2021
Respiratory Clinical Trials
2017
Oxidant-antioxidant imbalance forms a prime component in pathogenesis of chronic obstructive pulmonary disease (COPD). Studies oxidative stress markers South Asians were sparse.One hundred and eighty COPD patients healthy nonsmokers enrolled the study. Serum malondialdehyde (MDA) iron levels estimated for stress. Three antioxidant evaluated-catalase, superoxide dismutase (SOD), serum copper. Patients on therapy with sepsis illness excluded from study.The mean age was 59.29 ± 10.3 years. MDA...
Introduction Among chronic respiratory diseases, bronchiectasis is one of the important causes mortality and morbidity in developing countries. Objective This study aimed to assess clinical, radiological, microbiological, pulmonary function profiles adult patients with post-tubercular bronchiectasis. Methods We enrolled 138 confirmed by high-resolution CT scans from July 2017 August 2018. Results A total were enrolled. The data 132 analyzed; six excluded study. mean age post-TB...
Cigarette smoking is the most predominant risk factor for development of chronic obstructive pulmonary disease (COPD). However, a considerable amount patients do develop COPD without exposure to cigarette smoking. We aimed analyze incidence, demographic and clinical profile nonsmoker subjects at tertiary care center.In this prospective observational study, 410 were screened dyspnea. On basis spirometry findings, 360 diagnosed as enrolled into study. Patients categorized 2 groups on habits...
Background: Bronchial asthma is one of the common chronic respiratory illnesses worldwide, with a global disease burden that affects approximately 300 million individuals. It 5-10% population in developed countries. India constitutes one-tenth burden, where an estimated 7 children are affected by this illness. Airway hyperresponsiveness or bronchial hyperreactivity exaggerated response to numerous exogenous and endogenous stimuli. In India, most important stimuli considered be fungal...
COVID-19 pandemic had adversely affected the services of National Tuberculosis (TB) Elimination Programme, resulting in psychological distress among pulmonary tuberculosis patients (PTB). This cross-sectional, hospital-based study included 361 PTB patients. Three pre-defined questionnaires were used for analysis, a questionnaire to evaluate anxiety related COVID-19, patient health (PHQ-9) depression, and fear scale (FCV-19S) questionnaire. Among patients, 13% (n=47) infection. Out total 69%...
To determine the risk of obstructive sleep apnea (OSA) for male permanent driving license (DL) applicants Lucknow, India.In this cross-sectional community based, study body mass index, waist-hip ratio, blood pressure each subject were determined as an anthropometric parameter along with history habit smoking, tobacco chewing, alcohol consumption. STOP-Bang (Snoring, Tired or sleepy, Observed apnea, high Pressure, Body Age, Neck, Gender) Questionnaire - a scoring assessment tool was applied...
Interstitial lung diseases (ILDs) are an intriguing group of pulmonary disorders, which still require the study epidemiological, genetic, pathophysiological, clinical, and radiological parameters. Pulmonary hypertension (PH) is underreported complication in interstitial associated with worse outcome. In our study, we have reported spectrum ILDs estimated prevalence among these subjects at a tertiary care centre. A cross-sectional was performed demographical, radiological, histological data...
Background: Lung cancer now constitutes the majority of all diagnosis in world. It has most unfavourable prognosis accounting for maximum number related deaths worldwide. The objective this study was to complete profile lung cancer. Prevalence EGFR mutation adenocarcinoma.Methods: 116 patients were enrolled. They subjected diagnostic procedures like transthoracic FNAC/biopsy, bronchoscopy, thoracoscopy, closed pleural biopsy, lymph node besides routine blood and sputum examinations CECT...
Newer coexisting conditions should be identified in order to modify newer risk factors. Aim was identify patients with non-classical or less common infected of COVID 19.
Tuberculosis is notorious that it affects various sites of the human body and presents in different ways. One uncommon or rather rare presentation extra pulmonary tuberculosis nasal tuberculosis. The nose apart from its physiological functions also contributes to facial aesthetics gives a defined appearance deformity imparts cosmetic disfigurement unsightly appearance. Both primary secondary forms are but should be considered differential diagnosis ulcerative crusting lesions nose. Here we...
Abstract Pulmonary sequestration and cystic pulmonary adenomatoid malformation are rare congenital disorders of the lungs. The presence both diseases in same individual is therefore very uncommon. a nonfunctional tissue mass that derives its blood supply from systemic other than circulation. Congenital represents consisting abnormal bronchiolar air spaces deficiency functional alveoli. This case report 9-year-old girl with intermittent fever, left-sided chest pain, cough for past 15 days...
Aims: To compare the lung functions of TOPD phenotype patients and COPD other than phenotype. Settings design: Retro-prospective cohort study. Introduction: Globally, tuberculosis (TB) has emerged as a risk factor for development chronic obstructive pulmonary disease (COPD) is one leading causes mortality morbidity. This entity been titled (tuberculosis-associated disease), it mentioned in various literatures past by authors. However, still matter debate whether pattern airflow obstruction...
The COVID-19 pandemic has mainly affected the lungs, including many other organs. Many of patients later developed pulmonary fibrosis. This study was planned to determine fibrosis determinants in post-COVID survivors. Hospital-based, cross-sectional done over one year. A pre-designed proforma used collect necessary information, and follow-up HRCT investigations were evaluated. Out 87 patients, 41.3%(n=36) fibrosis; majority, i.e.,66.6%(n=24), males. Most them, 49.42%(n=43), belonged age...
Abstract Background As the pulmonary system and cardiovascular are intimately linked, patients with chronic obstructive disease (COPD) asthma have high risk for developing diseases (CVDs) altered central hemodynamic. Objective We aim to assess aortic blood pressure (CABP) indices, pulse wave velocity (PWV) other indicators of arterial stiffness in Indian COPD bronchial asthma. Methods This is a single‐center, cross‐sectional study conducted outpatients diagnosed either stable phase or CABP...
Objective : To study the symptoms, pulse oximetric and spirometric parameters in smokers with respect to pack years know effects of smoking on lung function, adults, by measuring FEV 1 , FVC, /FVC, FEF 25-75 . Patients Methods The current was an observational cross sectional conducted a tertiary care hospital over period one year. 100 subjects more than 21 age, smokers, who had been for 2 or more, whether symptomatic asymptomatic were recruited. Spirometry oximetry done. Results 93% our no...
Pulmonary pneumatoceles are thin-walled, air-filled cystic lesions occurring in lung parenchyma. They occur as a sequelae to bacterial infections of the lung, especially bronchopneumonia. commonly seen infants and children. In this article, we report rare case 40-year-old adult following staphylococcal community-acquired pneumonia.
Churg-Strauss syndrome (CSS) is an uncommon systemic disorder leading to inflammation of small and medium vessels by immunological mechanism. Lungs are the most frequent organ affected. It allergic granulomatosis with polyangiitis associated presence perinuclear antineutrophil cytoplasmic antibody. We describe a rare presentation CSS as bilateral multiple cavitating nodules in 50-year-old man diabetes.
<b>Background:</b> Approximately 1.3 million people are killed due to traffic accidents worldwide every year. . Persons with Obstructive Sleep Apnea (OSA) have elevated risk of falling asleep while driving and more likely cause accidents. Although 15-20% Indian males appeared in the OSA, screening for OSA licence applicants has not been mentioned medical fitness guidelines India. <b>Aims objectives:</b> This study was performed estimate male permanent recipients Lucknow, India...
Background. Pulmonary hypertension is a dreaded disease associated with considerable morbidity and mortality. The pulmonary developing due to chronic respiratory unique subset symptoms often getting masqueraded by the underlying condition. importance of early detection this complication has been realized worldwide, recently, definition was revised set cutoff mean artery pressure (mPAP) at 20 mmHg instead 25 rest. In our study, we have tried estimate difference new brings prevalence among...
Background: Health care workers (HCWs) are more likely to be at high risk of SARS-CoV-2 infection due their direct and/or indirect participation in treatment facilities. Here, we aimed evaluate the knowledge, attitude, and practices ivermectin pre-exposure prophylaxis (PEP) HCWs. Materials Methods: In this observational study HCWs who were directly/indirectly involved medication COVID-19 patients selected. The questionnaire included demographic data; attitudes, practices, associated adverse...